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F5H629

- F5H629_HUMAN

UniProt

F5H629 - F5H629_HUMAN

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Protein
Submitted name:

Cyclic AMP-dependent transcription factor ATF-2

Gene

ATF2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. cAMP response element binding Source: Ensembl
  2. chromatin binding Source: Ensembl
  3. metal ion binding Source: InterPro
  4. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
  5. sequence-specific DNA binding Source: InterPro

GO - Biological processi

  1. adipose tissue development Source: Ensembl
  2. fat cell differentiation Source: Ensembl
  3. outflow tract morphogenesis Source: Ensembl
  4. positive regulation of transforming growth factor beta2 production Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic AMP-dependent transcription factor ATF-2Imported
Gene namesi
Name:ATF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:784. ATF2.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: Ensembl
  2. nucleus Source: HPA
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF5H629.
ExpressionAtlasiF5H629. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H629.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000020106.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR004827. bZIP.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
SMARTiSM00338. BRLZ. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H629-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAYKFQIIQ QAVPSPTSST VITQAPSSNR PIVPVPGPFP LLLHLPNGQT
60 70 80 90 100
MPVAIPASIT SSNVHVPAAV PLVRPVTMVP SVPGIPGPSS PQPVQSEAKM
110 120 130 140 150
RLKAALTQQH PPVTNGDTVK GHGSGLVRTQ SEESRPQSLQ QPATSTTETP
160 170 180 190 200
ASPAHTTPQT QSTSGRRRRA ANEDPDEKRR KFLERNRAAA SRCRQKRKVW
210 220 230 240 250
VQSLEKKAED LSSLNGQLQS EVTLLRNEVA QLKQLLLAHK DCPVTAMQKK
260 270 280 290 300
SGYHTADKDD SSEDISVPSS PHTEAIQHSS VSTSNGVSST SKAEAVATSV
310 320
LTQMADQSTE PALSQIVMAP SSQSQPSGS
Length:329
Mass (Da):35,019
Last modified:October 29, 2014 - v2
Checksum:iE7EB4E349F7FA8F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007435 Genomic DNA. No translation available.
AC074291 Genomic DNA. No translation available.
AC096649 Genomic DNA. No translation available.
AC131958 Genomic DNA. No translation available.
KF456745 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000538946; ENSP00000437952; ENSG00000115966.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007435 Genomic DNA. No translation available.
AC074291 Genomic DNA. No translation available.
AC096649 Genomic DNA. No translation available.
AC131958 Genomic DNA. No translation available.
KF456745 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F5H629.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000538946 ; ENSP00000437952 ; ENSG00000115966 .

Organism-specific databases

HGNCi HGNC:784. ATF2.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000020106.

Miscellaneous databases

ChiTaRSi ATF2. human.
NextBioi 35509114.

Gene expression databases

Bgeei F5H629.
ExpressionAtlasi F5H629. baseline and differential.

Family and domain databases

Gene3Di 3.30.160.60. 1 hit.
InterProi IPR004827. bZIP.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00170. bZIP_1. 1 hit.
[Graphical view ]
SMARTi SM00338. BRLZ. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
PROSITEi PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
    Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.D., Yates J.R.
    J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5H629_HUMAN
AccessioniPrimary (citable) accession number: F5H629
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: October 29, 2014
Last modified: November 26, 2014
This is version 27 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3