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Protein
Submitted name:

Tyrosine-protein phosphatase non-receptor type 6

Gene

PTPN6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiF5H5H9.

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine-protein phosphatase non-receptor type 6Imported
Gene namesi
Name:PTPN6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111679.16.
HGNCiHGNC:9658. PTPN6.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111679.

PTM / Processingi

Proteomic databases

MaxQBiF5H5H9.
PeptideAtlasiF5H5H9.
PRIDEiF5H5H9.

Expressioni

Gene expression databases

BgeeiENSG00000111679.
ExpressionAtlasiF5H5H9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H5H9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 121SH2InterPro annotationAdd BLAST97

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0790. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00910000144001.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR000980. SH2.
IPR036860. SH2_dom_sf.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SUPFAMiSSF55550. SSF55550. 1 hit.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.

Sequencei

Sequence statusi: Fragment.

F5H5H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRGCTSSF PAPPSSPEAP RMVRWFHRDL SGLDAETLLK GRGVHGSFLA
60 70 80 90 100
RPSRKNQGDF SLSVRVGDQV THIRIQNSGD FYDLYGGEKF ATLTELVEYY
110 120 130
TQQQGVLQDR DGTIIHLKYP LNCSDPTSER
Length:130
Mass (Da):14,576
Last modified:June 28, 2011 - v1
Checksum:i7DE820EE9ABE95E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei130Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47924 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000543115; ENSP00000443393; ENSG00000111679.
UCSCiuc058koc.1. human.

Similar proteinsi

Entry informationi

Entry nameiF5H5H9_HUMAN
AccessioniPrimary (citable) accession number: F5H5H9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported