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Protein
Submitted name:

Serine/threonine-protein kinase 4

Gene

STK4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiF5H5B4.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase 4Imported
Gene namesi
Name:STK4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:11408. STK4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiF5H5B4.

Expressioni

Gene expression databases

BgeeiENSG00000101109.
ExpressionAtlasiF5H5B4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H5B4.
SMRiF5H5B4. Positions 21-258, 377-425.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 226226Protein kinaseInterPro annotationAdd
BLAST
Domaini378 – 42548SARAHInterPro annotationAdd
BLAST

Phylogenomic databases

GeneTreeiENSGT00810000125395.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR024205. Mst1_SARAH_domain.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR011524. SARAH_dom.
[Graphical view]
PfamiPF11629. Mst1_SARAH. 1 hit.
PF00069. Pkinase. 2 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS50951. SARAH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H5B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METVQLRNPP RRQLKKLDED SLTKQPEEVF DVLEKLGEGS YGSVYKAIHK
60 70 80 90 100
ETGQIVAIKQ VPVESDLQEI IKEISIMQQC DSPHVVKYYG SYFKNTDLWI
110 120 130 140 150
VMEYCGAGSV SDIIRLRNKT DTMAKRNTVI GTPFWMAPEV IQEIGYNCVA
160 170 180 190 200
DIWSLGITAI EMAEGKPPYA DIHPMRAIFM IPTNPPPTFR KPELWSDNFT
210 220 230 240 250
DFVKQCLVKS PEQRATATQL LQHPFVRSAK GVSILRDLIN EAMDVKLKRQ
260 270 280 290 300
ESQQREVDQD DEENSEEDEM DSGTMVRAVG DEMGTVRVAS TMTDGANTMI
310 320 330 340 350
EHDDTLPSQL GTMVINAEDE EEEGTMKRRD ETMQPAKPSF LEYFEQKEKE
360 370 380 390 400
NQINSFGKSV PGPLKNSSDW KIPQDGDYEF LKSWTVEDLQ KRLLALDPMM
410 420 430
EQEIEEIRQK YQSKRQPILD AIEAKKRRQQ NF
Length:432
Mass (Da):49,542
Last modified:June 28, 2011 - v1
Checksum:i386D7A92631E13FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109839 Genomic DNA. No translation available.
Z93016 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000499879; ENSP00000443514; ENSG00000101109.
UCSCiuc010ggy.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109839 Genomic DNA. No translation available.
Z93016 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5H5B4.
SMRiF5H5B4. Positions 21-258, 377-425.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiF5H5B4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000499879; ENSP00000443514; ENSG00000101109.
UCSCiuc010ggy.4. human.

Organism-specific databases

HGNCiHGNC:11408. STK4.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00810000125395.

Enzyme and pathway databases

SignaLinkiF5H5B4.

Miscellaneous databases

ChiTaRSiSTK4. human.

Gene expression databases

BgeeiENSG00000101109.
ExpressionAtlasiF5H5B4. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR024205. Mst1_SARAH_domain.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR011524. SARAH_dom.
[Graphical view]
PfamiPF11629. Mst1_SARAH. 1 hit.
PF00069. Pkinase. 2 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS50951. SARAH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5H5B4_HUMAN
AccessioniPrimary (citable) accession number: F5H5B4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 7, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.