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Protein
Submitted name:

Serine/threonine-protein kinase 4

Gene

STK4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF5H5B4

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase 4Imported
Gene namesi
Name:STK4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000101109.11
HGNCiHGNC:11408 STK4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101109

PTM / Processingi

Proteomic databases

EPDiF5H5B4
MaxQBiF5H5B4
PeptideAtlasiF5H5B4
PRIDEiF5H5B4

Expressioni

Gene expression databases

BgeeiENSG00000101109
ExpressionAtlasiF5H5B4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H5B4
SMRiF5H5B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 226Protein kinaseInterPro annotationAdd BLAST226
Domaini378 – 425SARAHInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili235 – 255Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00900000140794

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR024205 Mst1_SARAH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR011524 SARAH_dom
PfamiView protein in Pfam
PF11629 Mst1_SARAH, 1 hit
PF00069 Pkinase, 2 hits
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50951 SARAH, 1 hit

Sequencei

Sequence statusi: Complete.

F5H5B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METVQLRNPP RRQLKKLDED SLTKQPEEVF DVLEKLGEGS YGSVYKAIHK
60 70 80 90 100
ETGQIVAIKQ VPVESDLQEI IKEISIMQQC DSPHVVKYYG SYFKNTDLWI
110 120 130 140 150
VMEYCGAGSV SDIIRLRNKT DTMAKRNTVI GTPFWMAPEV IQEIGYNCVA
160 170 180 190 200
DIWSLGITAI EMAEGKPPYA DIHPMRAIFM IPTNPPPTFR KPELWSDNFT
210 220 230 240 250
DFVKQCLVKS PEQRATATQL LQHPFVRSAK GVSILRDLIN EAMDVKLKRQ
260 270 280 290 300
ESQQREVDQD DEENSEEDEM DSGTMVRAVG DEMGTVRVAS TMTDGANTMI
310 320 330 340 350
EHDDTLPSQL GTMVINAEDE EEEGTMKRRD ETMQPAKPSF LEYFEQKEKE
360 370 380 390 400
NQINSFGKSV PGPLKNSSDW KIPQDGDYEF LKSWTVEDLQ KRLLALDPMM
410 420 430
EQEIEEIRQK YQSKRQPILD AIEAKKRRQQ NF
Length:432
Mass (Da):49,542
Last modified:June 28, 2011 - v1
Checksum:i386D7A92631E13FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109839 Genomic DNA No translation available.
Z93016 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000499879; ENSP00000443514; ENSG00000101109
UCSCiuc010ggy.4 human

Similar proteinsi

Entry informationi

Entry nameiF5H5B4_HUMAN
AccessioniPrimary (citable) accession number: F5H5B4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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