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Protein
Submitted name:

Serine/threonine-protein kinase 4

Gene

STK4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF5H5B4.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase 4Imported
Gene namesi
Name:STK4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000101109.11.
HGNCiHGNC:11408. STK4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101109.

PTM / Processingi

Proteomic databases

MaxQBiF5H5B4.
PeptideAtlasiF5H5B4.
PRIDEiF5H5B4.

Expressioni

Gene expression databases

BgeeiENSG00000101109.
ExpressionAtlasiF5H5B4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H5B4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 226Protein kinaseInterPro annotationAdd BLAST226
Domaini378 – 425SARAHInterPro annotationAdd BLAST48

Phylogenomic databases

GeneTreeiENSGT00900000140794.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR024205. Mst1_SARAH_domain.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR011524. SARAH_dom.
PfamiView protein in Pfam
PF11629. Mst1_SARAH. 1 hit.
PF00069. Pkinase. 2 hits.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS50951. SARAH. 1 hit.

Sequencei

Sequence statusi: Complete.

F5H5B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METVQLRNPP RRQLKKLDED SLTKQPEEVF DVLEKLGEGS YGSVYKAIHK
60 70 80 90 100
ETGQIVAIKQ VPVESDLQEI IKEISIMQQC DSPHVVKYYG SYFKNTDLWI
110 120 130 140 150
VMEYCGAGSV SDIIRLRNKT DTMAKRNTVI GTPFWMAPEV IQEIGYNCVA
160 170 180 190 200
DIWSLGITAI EMAEGKPPYA DIHPMRAIFM IPTNPPPTFR KPELWSDNFT
210 220 230 240 250
DFVKQCLVKS PEQRATATQL LQHPFVRSAK GVSILRDLIN EAMDVKLKRQ
260 270 280 290 300
ESQQREVDQD DEENSEEDEM DSGTMVRAVG DEMGTVRVAS TMTDGANTMI
310 320 330 340 350
EHDDTLPSQL GTMVINAEDE EEEGTMKRRD ETMQPAKPSF LEYFEQKEKE
360 370 380 390 400
NQINSFGKSV PGPLKNSSDW KIPQDGDYEF LKSWTVEDLQ KRLLALDPMM
410 420 430
EQEIEEIRQK YQSKRQPILD AIEAKKRRQQ NF
Length:432
Mass (Da):49,542
Last modified:June 28, 2011 - v1
Checksum:i386D7A92631E13FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109839 Genomic DNA. No translation available.
Z93016 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000499879; ENSP00000443514; ENSG00000101109.
UCSCiuc010ggy.4. human.

Similar proteinsi

Entry informationi

Entry nameiF5H5B4_HUMAN
AccessioniPrimary (citable) accession number: F5H5B4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 25, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported