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F5H4T5

- F5H4T5_HUMAN

UniProt

F5H4T5 - F5H4T5_HUMAN

Protein
Submitted name:

Tumor necrosis factor receptor superfamily member 1A

Gene

TNFRSF1A

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. tumor necrosis factor-activated receptor activity Source: Ensembl

    GO - Biological processi

    1. cellular response to estradiol stimulus Source: Ensembl
    2. defense response to bacterium Source: Ensembl
    3. inflammatory response Source: Ensembl
    4. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    5. negative regulation of apoptotic process Source: Ensembl
    6. negative regulation of gene expression Source: Ensembl
    7. negative regulation of interleukin-6 production Source: Ensembl
    8. positive regulation of angiogenesis Source: Ensembl
    9. positive regulation of inflammatory response Source: Ensembl
    10. positive regulation of protein import into nucleus, translocation Source: Ensembl
    11. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    12. positive regulation of tumor necrosis factor production Source: Ensembl
    13. protein heterooligomerization Source: Ensembl
    14. response to alkaloid Source: Ensembl
    15. response to amino acid Source: Ensembl
    16. response to ethanol Source: Ensembl
    17. response to hypoxia Source: Ensembl
    18. response to lipopolysaccharide Source: Ensembl
    19. tetrapyrrole metabolic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Tumor necrosis factor receptor superfamily member 1AImported
    Gene namesi
    Name:TNFRSF1AImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:11916. TNFRSF1A.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. cell surface Source: Ensembl
    3. extracellular space Source: Ensembl
    4. membrane raft Source: Ensembl
    5. nucleus Source: Ensembl
    6. protein complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiF5H4T5.
    BgeeiF5H4T5.

    Structurei

    3D structure databases

    ProteinModelPortaliF5H4T5.
    SMRiF5H4T5. Positions 41-71.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
    [Graphical view]
    PfamiPF00020. TNFR_c6. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F5H4T5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLSTVPDLL LPLVLLELLV GIYPSGVIGL VPHLGDREKR DSVCPQGKYI   50
    HPQNNSICCT KCHKGTYLYN D 71
    Length:71
    Mass (Da):7,807
    Last modified:June 28, 2011 - v1
    Checksum:iBCB26BFA5D9BED63
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006057 Genomic DNA. No translation available.
    KF455591 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000543048; ENSP00000439981; ENSG00000067182.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006057 Genomic DNA. No translation available.
    KF455591 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F5H4T5.
    SMRi F5H4T5. Positions 41-71.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000543048 ; ENSP00000439981 ; ENSG00000067182 .

    Organism-specific databases

    HGNCi HGNC:11916. TNFRSF1A.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi TNFRSF1A. human.
    NextBioi 35508857.

    Gene expression databases

    ArrayExpressi F5H4T5.
    Bgeei F5H4T5.

    Family and domain databases

    InterProi IPR001368. TNFR/NGFR_Cys_rich_reg.
    [Graphical view ]
    Pfami PF00020. TNFR_c6. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The finished DNA sequence of human chromosome 12."
      Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF5H4T5_HUMAN
    AccessioniPrimary (citable) accession number: F5H4T5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3