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Protein
Submitted name:

Nuclear factor of-activated T-cells, cytoplasmic 1

Gene

NFATC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor of-activated T-cells, cytoplasmic 1Imported
Gene namesi
Name:NFATC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000131196.17
HGNCiHGNC:7775 NFATC1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131196

PTM / Processingi

Proteomic databases

MaxQBiF5H4S8
PeptideAtlasiF5H4S8
PRIDEiF5H4S8

Expressioni

Gene expression databases

BgeeiENSG00000131196
ExpressionAtlasiF5H4S8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H4S8
SMRiF5H4S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 120RHDInterPro annotationAdd BLAST120

Phylogenomic databases

eggNOGiENOG410IHFR Eukaryota
ENOG41105U2 LUCA
GeneTreeiENSGT00550000074562

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR008366 NFAT
IPR015647 NFAT1
IPR008967 p53-like_TF_DNA-bd
IPR032397 RHD_dimer
IPR011539 RHD_DNA_bind_dom
IPR037059 RHD_DNA_bind_dom_sf
PANTHERiPTHR12533 PTHR12533, 1 hit
PTHR12533:SF5 PTHR12533:SF5, 1 hit
PfamiView protein in Pfam
PF16179 RHD_dimer, 1 hit
PF00554 RHD_DNA_bind, 1 hit
PRINTSiPR01789 NUCFACTORATC
SMARTiView protein in SMART
SM00429 IPT, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS50254 REL_2, 1 hit

Sequencei

Sequence statusi: Complete.

F5H4S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQLFIGTAD DRLLRPHAFY QVHRITGKTV STTSHEAILS NTKVLEIPLL
60 70 80 90 100
PENSMRAVID CAGILKLRNS DIELRKGETD IGRKNTRVRL VFRVHVPQPS
110 120 130 140 150
GRTLSLQVAS NPIECSQRSA QELPLVEKQS TDSYPVVGGK KMVLSGHNFL
160 170 180 190 200
QDSKVIFVEK APDGHHVWEM EAKTDRDLCK PNSLVVEIPP FRNQRITSPV
210 220 230 240 250
HVSFYVCNGK RKRSQYQRFT YLPANVPIIK TEPTDDYEPA PTCGPVSQGL
260 270 280 290 300
SPLPRPYYSQ QLAMPPDPSS CLVAGFPPCP QRSTLMPAAP GVSPKLHDLS
310 320 330 340 350
PAAYTKGVAS PGHCHLGLPQ PAGEAPAVQD VPRPVATHPG SPGQPPPALL
360 370 380 390 400
PQQVSAPPSS SCPPGLEHSL CPSSPSPPLP PATQEPTCLQ PCSPACPPAT
410 420 430 440 450
GRPQHLPSTV RRDESPTAGP RLLPEVHEDG SPNLAPIPVT VKREPEELDQ
460 470
LYLDDVNEII RNDLSSTSTH S
Length:471
Mass (Da):51,106
Last modified:June 28, 2011 - v1
Checksum:i48519BBBB121A50C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018445 Genomic DNA No translation available.
AC023090 Genomic DNA No translation available.
RefSeqiNP_001265602.1, NM_001278673.1
UniGeneiHs.534074
Hs.701518

Genome annotation databases

EnsembliENST00000545796; ENSP00000439992; ENSG00000131196
GeneIDi4772
UCSCiuc010xfj.3 human

Similar proteinsi

Entry informationi

Entry nameiF5H4S8_HUMAN
AccessioniPrimary (citable) accession number: F5H4S8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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