F5H452 (F5H452_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Transcription factor Dp-1 Ensembl ENSP00000438450

Gene names

Name:

TFDP1 Ensembl ENSP00000438450

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000438450

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU003796.
Sequence similarities	Belongs to the E2F/DP family. RuleBase RU003796
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000438450

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU003796
Cellular component	Nucleus RuleBase RU003796
Ligand	DNA-binding RuleBase RU003796
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	transcription factor complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F5H452 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 0C6F89A2CCCD1BF7	FASTA	381	42,876
	10 20 30 40 50 60 MSTLPSKWKR NRKGEKNGKG LRHFSMKVCE KVQRKGTTSY NEVADELVAE FSAADNHILP 70 80 90 100 110 120 NESAYDQKNI RRRVYDALNV LMAMNIISKE KKEIKWIGLP TNSAQECQNL EVERQRRLER 130 140 150 160 170 180 IKQKQSQLQE LILQQIAFKN LVQRNRHAEQ QASRPPPPNS VIHLPFIIVN TSKKTVIDCS 190 200 210 220 230 240 ISNDKFEYLF NFDNTFEIHD DIEVLKRMGM ACGLESGSCS AEDLKMARSL VPKALEPYVT 250 260 270 280 290 300 EKTGLCDCTA GCPAPWRSVE NTGQAKDIRK LLQPSVLWNC ASFCWLPVRL VLFLFHDHSL 310 320 330 340 350 360 IFFPFSEMAQ GTVGGVFITT AGSTSNGTRF SASDLTNGAD GMLATSSNGS QYSGSRVETP 370 380 VSYVGEDDEE DDDFNENDED D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and analysis of human chromosome 13." Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T. Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL442125 Genomic DNA. No translation available.
IPI	IPI00922297.
3D structure databases
ProteinModelPortal	F5H452.
SMR	F5H452. Positions 18-100, 104-241.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000544902; ENSP00000438450; ENSG00000198176.
UCSC	uc010tke.2. human.
Organism-specific databases
HGNC	HGNC:11749. TFDP1.
GenAtlas	Search...
Gene expression databases
ArrayExpress	F5H452.
Bgee	F5H452.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR003316. E2F_TDP. IPR014889. Transc_factor_DP_C. IPR016556. Transcription_factor_DP_subgr. IPR015648. Transcrpt_fac_DP. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
PANTHER	PTHR12548. PTHR12548. 1 hit.
Pfam	PF08781. DP. 1 hit. PF02319. E2F_TDP. 1 hit. [Graphical view]
PIRSF	PIRSF009404. Transcription_factor_DP. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	TFDP1. human.
NextBio	35508725.

Entry information

Entry name

F5H452_HUMAN

Accession

Primary (citable) accession number: F5H452

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.