F5H3N5 (F5H3N5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitochondrial uncoupling protein 3 Ensembl ENSP00000445279

Gene names

Name:

UCP3 Ensembl ENSP00000445279

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000445279

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	96 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the mitochondrial carrier family. RuleBase RU000488
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000445279

Ontologies

Keywords
Biological process	Transport RuleBase RU000488
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS018108
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	aging Inferred from electronic annotation. Source: Compara cellular response to hormone stimulus Inferred from electronic annotation. Source: Compara fatty acid metabolic process Inferred from electronic annotation. Source: Compara mitochondrial transport Inferred from electronic annotation. Source: InterPro response to activity Inferred from electronic annotation. Source: Compara response to cold Inferred from electronic annotation. Source: Compara response to glucocorticoid stimulus Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara response to insulin stimulus Inferred from electronic annotation. Source: Compara response to nutrient Inferred from electronic annotation. Source: Compara response to superoxide Inferred from electronic annotation. Source: Compara
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	oxidative phosphorylation uncoupler activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	96	1	Ensembl ENSP00000445279

Sequences

	Sequence		Length	Mass (Da)
	F5H3N5 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 2B63A49E2B27959E	FASTA	96	10,254
	10 20 30 40 50 60 MVGLKPSDVP PTMAVKFLGA GTAACFADLV TFPLDTAKVR LQIQGENQAV QTARLVQYRG 70 80 90 VLGTILTMVR TEGPCSPYNG LVAGLQRQMS FASIRI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003717 Genomic DNA. No translation available.
IPI	IPI00953475.
3D structure databases
ProteinModelPortal	F5H3N5.
SMR	F5H3N5. Positions 13-96.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000544614; ENSP00000445279; ENSG00000175564.
Organism-specific databases
HGNC	HGNC:12519. UCP3.
GenAtlas	Search...
Gene expression databases
ArrayExpress	F5H3N5.
Bgee	F5H3N5.
Family and domain databases
Gene3D	1.50.40.10. 1 hit.
InterPro	IPR002030. Mit_uncoupling. IPR018108. Mitochondrial_sb/sol_carrier. IPR023395. Mt_carrier_dom. [Graphical view]
Pfam	PF00153. Mito_carr. 1 hit. [Graphical view]
PRINTS	PR00784. MTUNCOUPLING.
SUPFAM	SSF103506. Mitoch_carrier. 1 hit.
PROSITE	PS50920. SOLCAR. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35508644.

Entry information

Entry name

F5H3N5_HUMAN

Accession

Primary (citable) accession number: F5H3N5

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.