F5H335 (F5H335_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Eukaryotic translation initiation factor 3 subunit A Ensembl ENSP00000438178

Gene names

Name:

EIF3A Ensembl ENSP00000438178

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000438178

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1348 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000438178

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor SAAS SAAS000717
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	formation of translation initiation complex Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA eukaryotic translation initiation factor 3 complex Inferred from electronic annotation. Source: Compara nucleolus Inferred from direct assay. Source: HPA
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F5H335 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 97F42E357D8B5405	FASTA	1,348	162,636
	10 20 30 40 50 60 MKSKKHRTWQ KIHEPIMLKY LELCVDLRKS HLAKEGLYQY KNICQQVNIK SLEDVVRAYL 70 80 90 100 110 120 KMAEEKTEAA KEESQQMVLD IEDLDNIQTP ESVLLSAVSG EDTQDRTDRL LLTPWVKFLW 130 140 150 160 170 180 ESYRQCLDLL RNNSRVERLY HDIAQQAFKF CLQYTRKAEF RKLCDNLRMH LSQIQRHHNQ 190 200 210 220 230 240 STAINLNNPE SQSMHLETRL VQLDSAISME LWQEAFKAVE DIHGLFSLSK KPPKPQLMAN 250 260 270 280 290 300 YYNKVSTVFW KSGNALFHAS TLHRLYHLSR EMRKNLTQDE MQRMSTRVLL ATLSIPITPE 310 320 330 340 350 360 RTDIARLLDM DGIIVEKQRR LATLLGLQAP PTRIGLINDM VRFNVLQYVV PEVKDLYNWL 370 380 390 400 410 420 EVEFNPLKLC ERVTKVLNWV REQPEKEPEL QQYVPQLQNN TILRLLQQVS QIYQSIEFSR 430 440 450 460 470 480 LTSLVPFVDA FQLERAIVDA ARHCDLQVRI DHTSRTLSFG SDLNYATRED APIGPHLQSM 490 500 510 520 530 540 PSEQIRNQLT AMSSVLAKAL EVIKPAHILQ EKEEQHQLAV TAYLKNSRKE HQRILARRQT 550 560 570 580 590 600 IEERKERLES LNIQREKEEL EQREAELQKV RKAEEERLRQ EAKEREKERI LQEHEQIKKK 610 620 630 640 650 660 TVRERLEQIK KTELGAKAFK DIDIEDLEEL DPDFIMAKQV EQLEKEKKEL QERLKNQEKK 670 680 690 700 710 720 IDYFERAKRL EEIPLIKSAY EEQRIKDMDL WEQQEEERIT TMQLEREKAL EHKNRMSRML 730 740 750 760 770 780 EDRDLFVMRL KAARQSVYEE KLKQFEERLA EERHNRLEER KRQRKEERRI TYYREKEEEE 790 800 810 820 830 840 QRRAEEQMLK EREERERAER AKREEELREY QERVKKLEEV ERKKRQRELE IEERERRREE 850 860 870 880 890 900 ERRLGDSSLS RKDSRWGDRD SEGTWRKGPE ADSEWRRGPP EKEWRRGEGR DEDRSHRRDE 910 920 930 940 950 960 ERPRRLGDDE DREPSLRPDD DRVPRRGMDD DRGPRRGPEE DRFSRRGADD DRPSWRNTDD 970 980 990 1000 1010 1020 DRPPRRIADE DRGNWRHADD DRPPRRGLDE DRGSWRTADE DRGPRRGMDD DRGPRRGGAD 1030 1040 1050 1060 1070 1080 DERSSWRNAD DDRGPRRGLD DDRGPRRGMD DDRGPRRGMD DDRGPRRGMD DDRGPRRGLD 1090 1100 1110 1120 1130 1140 DDRGPWRNAD DDRIPRRGAE DDRGPWRNMD DDRLSRRADD DRFPRRGDDS RPGPWRPLVK 1150 1160 1170 1180 1190 1200 PGGWREKEKA REESWGPPRE SRPSEEREWD REKERDRDNQ DREENDKDPE RERDRERDVD 1210 1220 1230 1240 1250 1260 REDRFRRPRD EGGWRRGPAE ESSSWRDSSR RDDRDRDDRR RERDDRRDLR ERRDLRDDRD 1270 1280 1290 1300 1310 1320 RRGPPLRSER EEVSSWRRAD DRKDDRVEER DPPRRVPPPA LSRDRERDRD REREGEKEKA 1330 1340 SWRAEKDRES LRRTKNETDE DGWTTVRR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL355598 Genomic DNA. No translation available.
IPI	IPI01014951.
3D structure databases
ProteinModelPortal	F5H335.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000541549; ENSP00000438178; ENSG00000107581.
Organism-specific databases
HGNC	HGNC:3271. EIF3A.
GenAtlas	Search...
Gene expression databases
ArrayExpress	F5H335.
Bgee	F5H335.
Family and domain databases
InterPro	IPR000717. PCI_dom. [Graphical view]
Pfam	PF01399. PCI. 1 hit. [Graphical view]
SMART	SM00088. PINT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	EIF3A. human.
NextBio	35508544.

Entry information

Entry name

F5H335_HUMAN

Accession

Primary (citable) accession number: F5H335

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.