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Protein
Submitted name:

Cell division cycle and apoptosis regulator protein 1

Gene

CCAR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cell division cycle and apoptosis regulator protein 1Imported
Gene namesi
Name:CCAR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:24236. CCAR1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000060339.

PTM / Processingi

Proteomic databases

MaxQBiF5H1H2.
PaxDbiF5H1H2.
PeptideAtlasiF5H1H2.
PRIDEiF5H1H2.

Expressioni

Gene expression databases

BgeeiENSG00000060339.
ExpressionAtlasiF5H1H2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265872.

Structurei

3D structure databases

ProteinModelPortaliF5H1H2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini441 – 475SAPInterPro annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili399 – 423Sequence analysisAdd BLAST25
Coiled coili468 – 523Sequence analysisAdd BLAST56
Coiled coili602 – 629Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4246. Eukaryota.
ENOG410Z0UJ. LUCA.
GeneTreeiENSGT00530000063672.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
InterProiIPR025224. CCAR1/CCAR2.
IPR025954. DBC1/CARP1_inactive_NUDIX_dom.
IPR003034. SAP_dom.
[Graphical view]
PANTHERiPTHR14304. PTHR14304. 2 hits.
PfamiPF14443. DBC1. 1 hit.
PF02037. SAP. 1 hit.
[Graphical view]
SMARTiSM01122. DBC1. 1 hit.
SM00513. SAP. 1 hit.
[Graphical view]
PROSITEiPS50800. SAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F5H1H2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFKWNAQRI QTLPNQNQSQ TQPLLKTPPA VLQPIAPQTT FGVQTQPQPQ
60 70 80 90 100
SLLQAQISAA SITPLLQTQP QPLLQQPQQK AGLLQPPVRI VSQPQPARRL
110 120 130 140 150
DPPSRFSGRN DRGDQVPNRK DDRSRERERE RRRSRERSPQ RKRSRERSPR
160 170 180 190 200
RERERSPRRV RRVVPRYTVQ FSKFSLDCPS CDMMELRRRY QNLYIPSDFF
210 220 230 240 250
DAQFTWVDAF PLSRPFQLGN YCNFYVMHRE VESLEKNMAI LDPPDADHLY
260 270 280 290 300
SAKVMLMASP SMEDLYHKSC ALAEDPQELR DGFQHPARLV KFLVGMKGKD
310 320 330 340 350
EAMAIGGHWS PSLDGPDPEK DPSVLIKTAI RCCKALTGID LSVCTQWYRF
360 370 380 390 400
AEIRYHRPEE THKGRTVPAH VETVVLFFPD VWHCLPTRSE WETLSRGYKQ
410 420 430 440 450
QLVEKLQGER KEADGEQDEE EKDDGEAKEI STPTHWSKLD PKTMKVNDLR
460 470 480 490 500
KELESRALSS KGLKSQLIAR LTKQLKVEEQ KEEQKELEKS EKEEDEDDDR
510 520 530 540 550
KSEDDKEEEE RKRQEEIERQ RRERRYILPD EPAIIVHPNW AAKSGKFDCS
560 570 580 590 600
IMSLSVLLDY RLEDNKEHSF EVSLFAELFN EMLQRDFGVR IYKSLLSLPE
610 620 630 640
KEDKKEKDKK SKKDERKDKK EERDDETDEP KPKRRKSGDD KDKKED
Length:646
Mass (Da):75,724
Last modified:June 28, 2011 - v1
Checksum:iF8E90DF9E151FDA5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei646Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391539 Genomic DNA. No translation available.
AL513534 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000536012; ENSP00000439642; ENSG00000060339.
UCSCiuc057trt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391539 Genomic DNA. No translation available.
AL513534 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5H1H2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265872.

Proteomic databases

MaxQBiF5H1H2.
PaxDbiF5H1H2.
PeptideAtlasiF5H1H2.
PRIDEiF5H1H2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000536012; ENSP00000439642; ENSG00000060339.
UCSCiuc057trt.1. human.

Organism-specific databases

HGNCiHGNC:24236. CCAR1.
OpenTargetsiENSG00000060339.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4246. Eukaryota.
ENOG410Z0UJ. LUCA.
GeneTreeiENSGT00530000063672.

Miscellaneous databases

ChiTaRSiCCAR1. human.

Gene expression databases

BgeeiENSG00000060339.
ExpressionAtlasiF5H1H2. baseline and differential.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
InterProiIPR025224. CCAR1/CCAR2.
IPR025954. DBC1/CARP1_inactive_NUDIX_dom.
IPR003034. SAP_dom.
[Graphical view]
PANTHERiPTHR14304. PTHR14304. 2 hits.
PfamiPF14443. DBC1. 1 hit.
PF02037. SAP. 1 hit.
[Graphical view]
SMARTiSM01122. DBC1. 1 hit.
SM00513. SAP. 1 hit.
[Graphical view]
PROSITEiPS50800. SAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5H1H2_HUMAN
AccessioniPrimary (citable) accession number: F5H1H2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.