F5H0Q3 (F5H0Q3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyrin Ensembl ENSP00000438711

Gene names

Name:

MEFV Ensembl ENSP00000438711

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000438711

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	445 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 DAPIN domain. SAAS SAAS004020
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000438711

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F5H0Q3 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: E157099AC115F36C	FASTA	445	50,837
	10 20 30 40 50 60 MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP VKMATLLVTY 70 80 90 100 110 120 YGEEYAVQLT LQVLRAINQR LLAEELHRAA IQGRPPDTAA SPRCHAQEGD PVDGTCVRDS 130 140 150 160 170 180 CSFPEAVSGH PQASGSRSPG CPRCQDSHER KSPGSLSPQP LPQCKRHLKQ VQLLFCEDHD 190 200 210 220 230 240 EPICLICSLS QEHQGHRVRP IEEVALEHKK KIQKQLEHLK KLRKSGEEQR SYGEEKAVSF 250 260 270 280 290 300 LKQTEALKQR VQRKLEQVYY FLEQQEHFFV ASLEDVGQMV GQIRKAYDTR VSQDIALLDA 310 320 330 340 350 360 LIGELEAKEC QSEWELLQDI GDILHRAKTV PVPEKWTTPQ EIKQKIQLLH QKSEFVEKST 370 380 390 400 410 420 KYFSETLRSE MEMFNDHSPQ HGLGSWEERD YTQHSMQGPK QGVPCLSLLS GQCNLAPLNA 430 440 NAQDFFPYLI FLRSSGADWR SGTCC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence and analysis of duplication-rich human chromosome 16." Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A. Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ003147 Genomic DNA. No translation available.
IPI	IPI00954961.
3D structure databases
ProteinModelPortal	F5H0Q3.
SMR	F5H0Q3. Positions 13-88.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000541159; ENSP00000438711; ENSG00000103313.
UCSC	uc021tbw.1. human.
Organism-specific databases
HGNC	HGNC:6998. MEFV.
GenAtlas	Search...
Gene expression databases
ArrayExpress	F5H0Q3.
Bgee	F5H0Q3.
Family and domain databases
Gene3D	1.10.533.10. 1 hit.
InterPro	IPR004020. DAPIN. IPR011029. DEATH-like_dom. IPR000315. Znf_B-box. [Graphical view]
Pfam	PF02758. PYRIN. 1 hit. PF00643. zf-B_box. 1 hit. [Graphical view]
SMART	SM00336. BBOX. 1 hit. [Graphical view]
SUPFAM	SSF47986. DEATH_like. 1 hit.
PROSITE	PS50824. DAPIN. 1 hit. PS50119. ZF_BBOX. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35508066.

Entry information

Entry name

F5H0Q3_HUMAN

Accession

Primary (citable) accession number: F5H0Q3

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.