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F5H0N2

- F5H0N2_HUMAN

UniProt

F5H0N2 - F5H0N2_HUMAN

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Protein
Submitted name: Neuregulin-2
Gene
NRG2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. embryo development Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neuregulin-2Imported
Gene namesi
Name:NRG2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:7998. NRG2.

PTM / Processingi

Proteomic databases

PRIDEiF5H0N2.

Expressioni

Gene expression databases

ArrayExpressiF5H0N2.
BgeeiF5H0N2.

Structurei

3D structure databases

ProteinModelPortaliF5H0N2.
SMRiF5H0N2. Positions 249-330, 345-382.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR002154. Neuregulin_1_C.
[Graphical view]
PfamiPF12661. hEGF. 1 hit.
PF07679. I-set. 1 hit.
PF02158. Neuregulin. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 1 hit.
SM00408. IGc2. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H0N2-1 [UniParc]FASTAAdd to Basket

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MRQVCCSALP PPPLEKGRCS SYSDSSSSSS ERSSSSSSSS SESGSSSRSS    50
SNNSSISRPA APPEPRPQQQ PQPRSPAARR AAARSRAAAA GGMRRDPAPG 100
FSMLLFGVSL ACYSPSLKSV QDQAYKAPVV VEGKVQGLVP AGGSSSNSTR 150
EPPASGRVAL VKVLDKWPLR SGGLQREQVI SVGSCVPLER NQRYIFFLEP 200
TEQPLVFKTA FAPLDTNGKN LKKEVGKILC TDCATRPKLK KMKSQTGQVG 250
EKQSLKCEAA AGNPQPSYRW FKDGKELNRS RDIRIKYGNG RKNSRLQFNK 300
VKVEDAGEYV CEAENILGKD TVRGRLYVNS VSTTLSSWSG HARKCNETAK 350
SYCVNGGVCY YIEGINQLSC KCPVGYTGDR CQQFAMVNFS TRLGGDVEEA 400
EELYQKRVLT ITGICVALLV VGIVCVVAYC KTKKQRKQMH NHLRQNMCPA 450
HQNRSLANGP SHPRLDPEEI QMADYISKNV PATDHVIRRE TETTFSGSHS 500
CSPSHHCSTA TPTSSHRHES HTWSLERSES LTSDSQSGIM LSSVGTSKCN 550
SPACVEARAR RAAAYNLEER RRATAPPYHD SVDSLRDSPH SERYVSALTT 600
PARLSPVDFH YSLATQVPTF EITSPNSAHA VSLPPAAPIS YRLAEQQPLL 650
RHPAPPGPGP GPGPGPGPGA DMQRSYDSYY YPAAGPGPRR GTCALGGSLG 700
SLPASPFRIP EDDEYETTQE CAPPPPPRPR ARGASRRTSA GPRRWRRSRL 750
NGLAAQRARA ARDSLSLSSG SGGGSASASD DDADDADGAL AAESTPFLGL 800
RGAHDALRSD SPPLCPAADS RTYYSLDSHS TRASSRHSRG PPPRAKQDSA 850
PL 852
Length:852
Mass (Da):91,679
Last modified:June 28, 2011 - v1
Checksum:i0197574CCEC07EB6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008523 Genomic DNA. No translation available.
AC008667 Genomic DNA. No translation available.
AC010292 Genomic DNA. No translation available.
AC011379 Genomic DNA. No translation available.
AC094080 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000545385; ENSP00000438753; ENSG00000158458.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008523 Genomic DNA. No translation available.
AC008667 Genomic DNA. No translation available.
AC010292 Genomic DNA. No translation available.
AC011379 Genomic DNA. No translation available.
AC094080 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F5H0N2.
SMRi F5H0N2. Positions 249-330, 345-382.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F5H0N2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000545385 ; ENSP00000438753 ; ENSG00000158458 .

Organism-specific databases

HGNCi HGNC:7998. NRG2.
GenAtlasi Search...

Miscellaneous databases

NextBioi 35508053.

Gene expression databases

ArrayExpressi F5H0N2.
Bgeei F5H0N2.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR002154. Neuregulin_1_C.
[Graphical view ]
Pfami PF12661. hEGF. 1 hit.
PF07679. I-set. 1 hit.
PF02158. Neuregulin. 1 hit.
[Graphical view ]
SMARTi SM00181. EGF. 1 hit.
SM00408. IGc2. 1 hit.
[Graphical view ]
PROSITEi PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5H0N2_HUMAN
AccessioniPrimary (citable) accession number: F5H0N2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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