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Protein
Submitted name:

Transcription factor SOX-5

Gene

SOX5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi521 – 589HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor SOX-5Imported
Gene namesi
Name:SOX5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000134532.15
HGNCiHGNC:11201 SOX5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134532

PTM / Processingi

Proteomic databases

MaxQBiF5H0I3
PeptideAtlasiF5H0I3
PRIDEiF5H0I3

Expressioni

Gene expression databases

BgeeiENSG00000134532
ExpressionAtlasiF5H0I3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H0I3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini521 – 589HMG boxInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili160 – 180Sequence analysisAdd BLAST21
Coiled coili182 – 233Sequence analysisAdd BLAST52
Coiled coili418 – 445Sequence analysisAdd BLAST28
Coiled coili459 – 479Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0528 Eukaryota
ENOG410YZNG LUCA
GeneTreeiENSGT00760000119274

Family and domain databases

Gene3Di1.10.30.101 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

F5H0I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTDPDLPQE FERMSSKRPA SPYGEADGEV AMVTSRQKVE EEESDGLPAF
60 70 80 90 100
HLPLHEVDGN KVMSSFAPHN SSTSPQKAEE GGRQSGESLS STALGTPERR
110 120 130 140 150
KGSLADVVDT LKQRKMEELI KNEPEETPSI EKLLSKDWKD KLLAMGSGNF
160 170 180 190 200
GEIKGTPESL AEKERQLMGM INQLTSLREQ LLAAHDEQKK LAASQIEKQR
210 220 230 240 250
QQMELAKQQQ EQIARQQQQL LQQQHKINLL QQQIQVQGQL PPLMIPVFPP
260 270 280 290 300
DQRTLAAAAQ QGFLLPPGFS YKAGCSDPYP VQLIPTTMAA AAAATPGLGP
310 320 330 340 350
LQLQQLYAAQ LAAMQVSPGG KLPGIPQGNL GAAVSPTSIH TDKSTNSPPP
360 370 380 390 400
KSKDEVAQPL NLSAKPKTSD GKSPTSPTSP HMPALRINSG AGPLKASVPA
410 420 430 440 450
ALASPSARVS TIGYLNDHDA VTKAIQEARQ MKEQLRREQQ VLDGKVAVVN
460 470 480 490 500
SLGLNNCRTE KEKTTLESLT QQLAVKQNEE GKFSHAMMDF NLSGDSDGSA
510 520 530 540 550
GVSESRIYRE SRGRGSNEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN
560 570 580 590 600
ISKILGSRWK AMTNLEKQPY YEEQARLSKQ HLEKYPDYKY KPRPKRTCLV
610 620 630 640 650
DGKKLRIGEY KAIMRNRRQE MRQYFNVGQQ AQIPIATAGV VYPGAIAMAG
660 670 680 690 700
MPSPHLPSEH SSVSSSPEPG MPVIQSTYGV KGEEPHIKEE IQAEDINGEI
710 720
YDEYDEEEDD PDVDYGSDSE NHIAGQAN
Length:728
Mass (Da):80,077
Last modified:June 28, 2011 - v1
Checksum:iC465EFBA8009AC73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087244 Genomic DNA No translation available.
AC087260 Genomic DNA No translation available.
AC087319 Genomic DNA No translation available.
AC092864 Genomic DNA No translation available.
RefSeqiNP_001317714.1, NM_001330785.1
UniGeneiHs.434948
Hs.657542
Hs.742277

Genome annotation databases

EnsembliENST00000537393; ENSP00000439832; ENSG00000134532
GeneIDi6660
UCSCiuc058lyh.1 human

Similar proteinsi

Entry informationi

Entry nameiF5H0I3_HUMAN
AccessioniPrimary (citable) accession number: F5H0I3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported