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Protein
Submitted name:

Transcription factor SOX-5

Gene

SOX5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor SOX-5Imported
Gene namesi
Name:SOX5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:11201. SOX5.

PTM / Processingi

Proteomic databases

EPDiF5H0I3.
PaxDbiF5H0I3.
PeptideAtlasiF5H0I3.

Expressioni

Gene expression databases

BgeeiF5H0I3.
ExpressionAtlasiF5H0I3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000398273.

Structurei

3D structure databases

ProteinModelPortaliF5H0I3.
SMRiF5H0I3. Positions 519-588.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini521 – 58969HMG box DNA-bindingInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili182 – 23352Sequence analysisAdd
BLAST
Coiled coili418 – 44528Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0528. Eukaryota.
ENOG410YZNG. LUCA.
GeneTreeiENSGT00760000119274.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H0I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTDPDLPQE FERMSSKRPA SPYGEADGEV AMVTSRQKVE EEESDGLPAF
60 70 80 90 100
HLPLHEVDGN KVMSSFAPHN SSTSPQKAEE GGRQSGESLS STALGTPERR
110 120 130 140 150
KGSLADVVDT LKQRKMEELI KNEPEETPSI EKLLSKDWKD KLLAMGSGNF
160 170 180 190 200
GEIKGTPESL AEKERQLMGM INQLTSLREQ LLAAHDEQKK LAASQIEKQR
210 220 230 240 250
QQMELAKQQQ EQIARQQQQL LQQQHKINLL QQQIQVQGQL PPLMIPVFPP
260 270 280 290 300
DQRTLAAAAQ QGFLLPPGFS YKAGCSDPYP VQLIPTTMAA AAAATPGLGP
310 320 330 340 350
LQLQQLYAAQ LAAMQVSPGG KLPGIPQGNL GAAVSPTSIH TDKSTNSPPP
360 370 380 390 400
KSKDEVAQPL NLSAKPKTSD GKSPTSPTSP HMPALRINSG AGPLKASVPA
410 420 430 440 450
ALASPSARVS TIGYLNDHDA VTKAIQEARQ MKEQLRREQQ VLDGKVAVVN
460 470 480 490 500
SLGLNNCRTE KEKTTLESLT QQLAVKQNEE GKFSHAMMDF NLSGDSDGSA
510 520 530 540 550
GVSESRIYRE SRGRGSNEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN
560 570 580 590 600
ISKILGSRWK AMTNLEKQPY YEEQARLSKQ HLEKYPDYKY KPRPKRTCLV
610 620 630 640 650
DGKKLRIGEY KAIMRNRRQE MRQYFNVGQQ AQIPIATAGV VYPGAIAMAG
660 670 680 690 700
MPSPHLPSEH SSVSSSPEPG MPVIQSTYGV KGEEPHIKEE IQAEDINGEI
710 720
YDEYDEEEDD PDVDYGSDSE NHIAGQAN
Length:728
Mass (Da):80,077
Last modified:June 28, 2011 - v1
Checksum:iC465EFBA8009AC73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087244 Genomic DNA. No translation available.
AC087260 Genomic DNA. No translation available.
AC087319 Genomic DNA. No translation available.
AC092864 Genomic DNA. No translation available.
RefSeqiXP_011519133.1. XM_011520831.1.
UniGeneiHs.657542.

Genome annotation databases

EnsembliENST00000537393; ENSP00000439832; ENSG00000134532.
GeneIDi6660.
UCSCiuc058lyh.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087244 Genomic DNA. No translation available.
AC087260 Genomic DNA. No translation available.
AC087319 Genomic DNA. No translation available.
AC092864 Genomic DNA. No translation available.
RefSeqiXP_011519133.1. XM_011520831.1.
UniGeneiHs.657542.

3D structure databases

ProteinModelPortaliF5H0I3.
SMRiF5H0I3. Positions 519-588.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000398273.

Proteomic databases

EPDiF5H0I3.
PaxDbiF5H0I3.
PeptideAtlasiF5H0I3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000537393; ENSP00000439832; ENSG00000134532.
GeneIDi6660.
UCSCiuc058lyh.1. human.

Organism-specific databases

CTDi6660.
HGNCiHGNC:11201. SOX5.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0528. Eukaryota.
ENOG410YZNG. LUCA.
GeneTreeiENSGT00760000119274.

Miscellaneous databases

ChiTaRSiSOX5. human.
GenomeRNAii6660.

Gene expression databases

BgeeiF5H0I3.
ExpressionAtlasiF5H0I3. baseline and differential.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The finished DNA sequence of human chromosome 12."
    Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF5H0I3_HUMAN
AccessioniPrimary (citable) accession number: F5H0I3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 6, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.