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Protein
Submitted name:

Centrosomal protein of 57 kDa

Gene

CEP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. microtubule anchoring Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 57 kDaImported
Gene namesi
Name:CEP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:30794. CEP57.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. microtubule cytoskeleton Source: HPA
  3. nucleoplasm Source: HPA
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF5H0C6.
ExpressionAtlasiF5H0C6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H0C6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063695.

Family and domain databases

InterProiIPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
[Graphical view]
PANTHERiPTHR19336. PTHR19336. 1 hit.
PfamiPF14073. Cep57_CLD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F5H0C6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTRIDNSFA EPSRSNGSMV RHSSSPYVVY PSDKPFLNSD LRRSPSKPTL
60 70 80 90 100
AYPESNSRAI FSALKNLQDK IRRLELERIQ AEESVKTLSR ETIEYKKVLD
110 120 130 140 150
EQIQERENSK NEESKHNQEL TSQLLAAENK CNLLEKQLEY MRNMIKHAEM
160 170 180 190
ERTSVLEKQV SLERERQHDQ THVQSQLEKL DLLEQEYNKL TTMQALAE
Length:198
Mass (Da):23,180
Last modified:June 27, 2011 - v1
Checksum:i790B2DAAA7848DDA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei198 – 1981Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000544522; ENSP00000438065; ENSG00000166037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5H0C6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000544522; ENSP00000438065; ENSG00000166037.

Organism-specific databases

HGNCiHGNC:30794. CEP57.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063695.

Miscellaneous databases

NextBioi35507997.

Gene expression databases

BgeeiF5H0C6.
ExpressionAtlasiF5H0C6. baseline and differential.

Family and domain databases

InterProiIPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
[Graphical view]
PANTHERiPTHR19336. PTHR19336. 1 hit.
PfamiPF14073. Cep57_CLD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:rs3-RS3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5H0C6_HUMAN
AccessioniPrimary (citable) accession number: F5H0C6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 27, 2011
Last sequence update: June 27, 2011
Last modified: March 31, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationMaxQB annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.