Uncharacterized protein

Functionⁱ

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
nucleic acid binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

regulation of transcription, DNA-templated Source: InterPro

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Uncharacterized proteinImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Subcellular locationⁱ

GO - Cellular componentⁱ

intracellular Source: InterPro

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	F5H0A9.
PeptideAtlas More...PeptideAtlasⁱ	F5H0A9.
PRIDEⁱ	F5H0A9.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000197054.
ExpressionAtlasⁱ	F5H0A9. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000467286.

STRINGⁱ

9606.ENSP00000467286.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	F5H0A9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	24 – 106	KRABInterPro annotationAdd BLAST	83
Domainⁱ	164 – 191	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	192 – 219	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	220 – 247	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	248 – 275	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	276 – 303	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	304 – 331	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	332 – 359	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	360 – 387	C2H2-typeInterPro annotationAdd BLAST	28

Keywords - Domainⁱ

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119089.
OMAⁱ	SSFQAHK.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	F5H0A9.
TreeFamⁱ	TF338854.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07765. KRAB_A-box. 1 hit.
InterProⁱ	View protein in InterPro IPR001909. KRAB. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01352. KRAB. 1 hit.
SMARTⁱ	View protein in SMART SM00349. KRAB. 1 hit. SM00355. ZnF_C2H2. 7 hits.
SUPFAMⁱ	SSF109640. SSF109640. 1 hit. SSF57667. SSF57667. 4 hits.
PROSITEⁱ	View protein in PROSITE PS50805. KRAB. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 8 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

F5H0A9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPCCSHRSCR EDPGTSESRE MDPVACEDVA VNFTQEEWAL LDISQRKLYR 
        60         70         80         90        100
EVMLETFRNL TSIGKKWKDQ NIEYEYQNPR RNFRSLIEGN VNEIKEDSHC 
       110        120        130        140        150
GETFTQVPDD RLNFQEKKAS PEAKSCDNFV CGEVGIGNSS FNMNIRGDIG 
       160        170        180        190        200
HKAYEYQDYA PKPYKCQQPK KAFRYHPSFR TQERNHTGEK PYACKECGKT 
       210        220        230        240        250
FISHSGIRRR MVMHSGDGPY KCKFCGKAVH CLRLYLIHER THTGEKPYEC 
       260        270        280        290        300
KQCVKSFSYS ATHRIHERTH TGEKPYECQQ CGKAFHSSSS FQAHKRTHTG 
       310        320        330        340        350
GKPYECKQCG KSFSWCHSFQ IHERTHTGEK PCECSKCNKA FRSYRSYLRH 
       360        370        380        390        400
KRSHTGEKPY QCKECRKAFT YPSSLRRHER THSAKKPYEC KQCGKALSYK 
       410 
FSNTPKNALW RKTL

Length:414

Mass (Da):48,349

Last modified:June 28, 2011 - v1

Checksum:ⁱDD6F6C7F3C63854E

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC008770 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC008770 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000590798; ENSP00000467286; ENSG00000267179.
UCSC genome browser More...UCSCⁱ	uc010xmf.4. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC008770 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC008770 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	F5H0A9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000467286.

STRINGⁱ

9606.ENSP00000467286.

Proteomic databases

PaxDbⁱ	F5H0A9.
PeptideAtlas More...PeptideAtlasⁱ	F5H0A9.
PRIDEⁱ	F5H0A9.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000590798; ENSP00000467286; ENSG00000267179.
UCSC genome browser More...UCSCⁱ	uc010xmf.4. human.

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119089.
OMAⁱ	SSFQAHK.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	F5H0A9.
TreeFamⁱ	TF338854.

Gene expression databases

Bgeeⁱ	ENSG00000197054.
ExpressionAtlasⁱ	F5H0A9. baseline and differential.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07765. KRAB_A-box. 1 hit.
InterProⁱ	View protein in InterPro IPR001909. KRAB. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01352. KRAB. 1 hit.
SMARTⁱ	View protein in SMART SM00349. KRAB. 1 hit. SM00355. ZnF_C2H2. 7 hits.
SUPFAMⁱ	SSF109640. SSF109640. 1 hit. SSF57667. SSF57667. 4 hits.
PROSITEⁱ	View protein in PROSITE PS50805. KRAB. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 8 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F5H0A9_HUMAN
Accessionⁱ	F5H0A9Primary (citable) accession number: F5H0A9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 28, 2011
	Last sequence update:	June 28, 2011
	Last modified:	June 7, 2017
	This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F5H0A9 (F5H0A9_HUMAN)

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ