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Protein
Submitted name:

Nik-related protein kinase

Gene

NRK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiF5H049

Names & Taxonomyi

Protein namesi
Submitted name:
Nik-related protein kinaseImported
Gene namesi
Name:NRKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000123572.16
HGNCiHGNC:25391 NRK

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000123572

PTM / Processingi

Proteomic databases

PeptideAtlasiF5H049
PRIDEiF5H049

Expressioni

Gene expression databases

BgeeiENSG00000123572
ExpressionAtlasiF5H049 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H049
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 313Protein kinaseInterPro annotationAdd BLAST289

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0587 Eukaryota
ENOG410YEAG LUCA
GeneTreeiENSGT00900000140838
TreeFamiTF105138

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

F5H049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGPGGWRDR EVTDLGHLPD PTGIFSLDKT IGLGTYGRIY LGLHEKTGAF
60 70 80 90 100
TAVKVMNARK TPLPEIGRRV RVNKYQKSVG WRYSDEEEDL RTELNLLRKY
110 120 130 140 150
SFHKNIVSFY GAFFKLSPPG QRHQLWMVME LCAAGSVTDV VRMTSNQSLK
160 170 180 190 200
EDWIAYICRE ILQGLAHLHA HRVIHRDIKG QNVLLTHNAE VKLVDFGVSA
210 220 230 240 250
QVSRTNGRRN SFIGTPYWMA PEVIDCDEDP RRSYDYRSDV WSVGITAIEM
260 270 280 290 300
AEGAPPLCNL QPLEALFVIL RESAPTVKSS GWSRKFHNFM EKCTIKNFLF
310 320 330 340 350
RPTSANMLQH PFVRDIKNER HVVESLTRHL TGIIKKRQKK GFAVSQDHAT

ALQPG
Length:355
Mass (Da):40,387
Last modified:October 29, 2014 - v2
Checksum:iB149CF99453C8371
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF459286 Genomic DNA No translation available.
KF459287 Genomic DNA No translation available.
KF510615 Genomic DNA No translation available.
Z68339 Genomic DNA No translation available.
Z69734 Genomic DNA No translation available.
Z70274 Genomic DNA No translation available.
Z97356 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000428173; ENSP00000438378; ENSG00000123572
UCSCiuc065anu.1 human

Similar proteinsi

Entry informationi

Entry nameiF5H049_HUMAN
AccessioniPrimary (citable) accession number: F5H049
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: October 29, 2014
Last modified: May 23, 2018
This is version 53 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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