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F5GZZ9

- F5GZZ9_HUMAN

UniProt

F5GZZ9 - F5GZZ9_HUMAN

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Protein
Submitted name: Scavenger receptor cysteine-rich type 1 protein M130
Gene
CD163
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. scavenger receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Scavenger receptor cysteine-rich type 1 protein M130Imported
    Gene namesi
    Name:CD163Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:1631. CD163.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro
    Complete GO annotation...

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotations

    Expressioni

    Gene expression databases

    ArrayExpressiF5GZZ9.
    BgeeiF5GZZ9.

    Structurei

    3D structure databases

    ProteinModelPortaliF5GZZ9.
    SMRiF5GZZ9. Positions 36-252, 265-354, 361-461, 467-671, 702-812, 825-1018.

    Family & Domainsi

    Family and domain databases

    Gene3Di3.10.250.10. 9 hits.
    InterProiIPR001190. SRCR.
    IPR017448. SRCR-like_dom.
    [Graphical view]
    PfamiPF00530. SRCR. 9 hits.
    [Graphical view]
    PRINTSiPR00258. SPERACTRCPTR.
    SMARTiSM00202. SR. 9 hits.
    [Graphical view]
    SUPFAMiSSF56487. SSF56487. 9 hits.
    PROSITEiPS00420. SRCR_1. 4 hits.
    PS50287. SRCR_2. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F5GZZ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLDFRRHFV NLSPFTITVV LLLSACFVTS SLGGTDKELR LVDGENKCSG     50
    RVEVKVQEEW GTVCNNGWSM EAVSVICNQL GCPTAIKAPG WANSSAGSGR 100
    IWMDHVSCRG NESALWDCKH DGWGKHSNCT HQQDAGVTCS DGSNLEMRLT 150
    RGGNMCSGRI EIKFQGRWGT VCDDNFNIDH ASVICRQLEC GSAVSFSGSS 200
    NFGEGSGPIW FDDLICNGNE SALWNCKHQG WGKHNCDHAE DAGVICSKGA 250
    DLSLRLVDGV TECSGRLEVR FQGEWGTICD DGWDSYDAAV ACKQLGCPTA 300
    VTAIGRVNAS KGFGHIWLDS VSCQGHEPAI WQCKHHEWGK HYCNHNEDAG 350
    VTCSDGSDLE LRLRGGGSRC AGTVEVEIQR LLGKVCDRGW GLKEADVVCR 400
    QLGCGSALKT SYQVYSKIQA TNTWLFLSSC NGNETSLWDC KNWQWGGLTC 450
    DHYEEAKITC SAHREPRLVG GDIPCSGRVE VKHGDTWGSI CDSDFSLEAA 500
    SVLCRELQCG TVVSILGGAH FGEGNGQIWA EEFQCEGHES HLSLCPVAPR 550
    PEGTCSHSRD VGVVCSRYTE IRLVNGKTPC EGRVELKTLG AWGSLCNSHW 600
    DIEDAHVLCQ QLKCGVALST PGGARFGKGN GQIWRHMFHC TGTEQHMGDC 650
    PVTALGASLC PSEQVASVIC SGNQSQTLSS CNSSSLGPTR PTIPEESAVA 700
    CIESGQLRLV NGGGRCAGRV EIYHEGSWGT ICDDSWDLSD AHVVCRQLGC 750
    GEAINATGSA HFGEGTGPIW LDEMKCNGKE SRIWQCHSHG WGQQNCRHKE 800
    DAGVICSEFM SLRLTSEASR EACAGRLEVF YNGAWGTVGK SSMSETTVGV 850
    VCRQLGCADK GKINPASLDK AMSIPMWVDN VQCPKGPDTL WQCPSSPWEK 900
    RLASPSEETW ITCDNKIRLQ EGPTSCSGRV EIWHGGSWGT VCDDSWDLDD 950
    AQVVCQQLGC GPALKAFKEA EFGQGTGPIW LNEVKCKGNE SSLWDCPARR 1000
    WGHSECGHKE DAAVNCTDIS VQKTPQKATT GRSSRQSSFI AVGILGVVLL 1050
    AIFVALFFLT KKRRQRQRLA VSSRGENLVH QIQYREMNSC LNADDLDLMN 1100
    SSGGHSEPH 1109
    Length:1,109
    Mass (Da):120,322
    Last modified:June 28, 2011 - v1
    Checksum:i50B73BFE15FD32EA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC131206 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000541972; ENSP00000444071; ENSG00000177575.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC131206 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F5GZZ9.
    SMRi F5GZZ9. Positions 36-252, 265-354, 361-461, 467-671, 702-812, 825-1018.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000541972 ; ENSP00000444071 ; ENSG00000177575 .

    Organism-specific databases

    HGNCi HGNC:1631. CD163.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi CD163. human.
    NextBioi 35507923.

    Gene expression databases

    ArrayExpressi F5GZZ9.
    Bgeei F5GZZ9.

    Family and domain databases

    Gene3Di 3.10.250.10. 9 hits.
    InterProi IPR001190. SRCR.
    IPR017448. SRCR-like_dom.
    [Graphical view ]
    Pfami PF00530. SRCR. 9 hits.
    [Graphical view ]
    PRINTSi PR00258. SPERACTRCPTR.
    SMARTi SM00202. SR. 9 hits.
    [Graphical view ]
    SUPFAMi SSF56487. SSF56487. 9 hits.
    PROSITEi PS00420. SRCR_1. 4 hits.
    PS50287. SRCR_2. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The finished DNA sequence of human chromosome 12."
      Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF5GZZ9_HUMAN
    AccessioniPrimary (citable) accession number: F5GZZ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: July 9, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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