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F5GZW3 (F5GZW3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Rho GTPase-activating protein 4 Ensembl ENSP00000444169
Gene names
Name:ARHGAP4 Ensembl ENSP00000444169
OrganismHomo sapiens (Human) [Reference proteome] Ensembl ENSP00000444169
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length923 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000444169

Sequences

Sequence LengthMass (Da)Tools
F5GZW3 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: D552024DC78AD482

FASTA923102,343
        10         20         30         40         50         60 
MRWQLSEQLR CLELQGELRR ELLQELAEFM RRRAEVELEY SRGLEKLAER FSSRGGRLGS 

        70         80         90        100        110        120 
SREHQSFRKE PSLLSPLHCW AVLLQHTRQQ SRESAALSEV LAGPLAQRLS HIAEDVGRLV 

       130        140        150        160        170        180 
KKSRDLEQQL QDELLEVVSE LQTAKKTYQA YHMESVNAEA KLREAERQEE KRAGRSVPTT 

       190        200        210        220        230        240 
TAGATEAGPL RKSSLKKGGR LVEKRQAKFM EHKLKCTKAR NEYLLSLASV NAAVSNYYLH 

       250        260        270        280        290        300 
DVLDLMDCCD TGFHLALGQV LRSYTAAESR TQASQVQGLG SLEEAVEALD PPGDKAKVLE 

       310        320        330        340        350        360 
VHATVFCPPL RFDYHPHDGD EVAEICVEME LRDEILPRAQ NIQSRLDRQT IETEEVNKTL 

       370        380        390        400        410        420 
KATLQALLEV VASDDGDVLD SFQTSPSTES LKSTSSDPGS RQAGRRRGQQ QETETFYLTK 

       430        440        450        460        470        480 
LQEYLSGRSI LAKLQAKHEK LQEALQRGDK EEQEVSWTQY TQRKFQKSRQ PRPSSQYNQR 

       490        500        510        520        530        540 
LFGGDMEKFI QSSGQPVPLV VESCIRFINL NGLQHEGIFR VSGAQLRVSE IRDAFERGED 

       550        560        570        580        590        600 
PLVEGCTAHD LDSVAGVLKL YFRSLEPPLF PPDLFGELLA SSELEATAER VEHVSRLLWR 

       610        620        630        640        650        660 
LPAPVLVVLR YLFTFLNHLA QYSDENMMDP YNLAVCFGPT LLPVPAGQDP VALQGRVNQL 

       670        680        690        700        710        720 
VQTLIVQPDR VFPPLTSLPG PVYEKCMAPP SASCLGDAQL ESLGADNEPE LEAEMPAQED 

       730        740        750        760        770        780 
DLEGVVEAVA CFAYTGRTAQ ELSFRRGDVL RLHERASSDW WRGEHNGMRG LIPHKYITLP 

       790        800        810        820        830        840 
AGTEKQVVGA GLQTAGESGS SPEGLLASEL VHRPEPCTSP EAMGPSGHRR RCLVPASPEQ 

       850        860        870        880        890        900 
HVEVDKAVAQ NMDSVFKELL GKTSVRQGLG PASTTSPSPG PRSPKAPPSS RLGRNKGFSR 

       910        920 
GPGAPASPSA SHPQGLDTTP KPH

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence of the human X chromosome."
Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. expand/collapse author list , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U52112 Genomic DNA. No translation available.
IPIIPI00852636.

3D structure databases

ProteinModelPortalF5GZW3.
SMRF5GZW3. Positions 479-672, 728-825.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000537206; ENSP00000444169; ENSG00000089820.

Organism-specific databases

HGNCHGNC:674. ARHGAP4.
GenAtlasSearch...

Gene expression databases

ArrayExpressF5GZW3.
BgeeF5GZW3.

Family and domain databases

Gene3D1.10.555.10. 1 hit.
InterProIPR001060. FCH_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamPF00611. FCH. 1 hit.
PF00620. RhoGAP. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTSM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF48350. Rho_GAP. 1 hit.
SSF50044. SH3. 1 hit.
PROSITEPS50133. FCH. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35507899.

Entry information

Entry nameF5GZW3_HUMAN
AccessionPrimary (citable) accession number: F5GZW3
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info