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Protein
Submitted name:

Trifunctional enzyme subunit beta, mitochondrial

Gene

HADHB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Trifunctional enzyme subunit beta, mitochondrialImported
Gene namesi
Name:HADHBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000138029.13
HGNCiHGNC:4803 HADHB

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138029

PTM / Processingi

Proteomic databases

MaxQBiF5GZQ3
PeptideAtlasiF5GZQ3
PRIDEiF5GZQ3

Expressioni

Gene expression databases

BgeeiENSG00000138029
ExpressionAtlasiF5GZQ3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5GZQ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 309Thiolase_NInterPro annotationAdd BLAST240
Domaini316 – 455Thiolase_CInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the thiolase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1392 Eukaryota
COG0183 LUCA
GeneTreeiENSGT00910000144143

Family and domain databases

CDDicd00751 thiolase, 1 hit
Gene3Di3.40.47.10, 1 hit
InterProiView protein in InterPro
IPR002155 Thiolase
IPR016039 Thiolase-like
IPR020615 Thiolase_acyl_enz_int_AS
IPR020610 Thiolase_AS
IPR020617 Thiolase_C
IPR020613 Thiolase_CS
IPR020616 Thiolase_N
PfamiView protein in Pfam
PF02803 Thiolase_C, 1 hit
PF00108 Thiolase_N, 1 hit
SUPFAMiSSF53901 SSF53901, 2 hits
TIGRFAMsiTIGR01930 AcCoA-C-Actrans, 1 hit
PROSITEiView protein in PROSITE
PS00098 THIOLASE_1, 1 hit
PS00737 THIOLASE_2, 1 hit
PS00099 THIOLASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

F5GZQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTILTYPFKN LPTASKWALR FSIRPLSCSS QLRAAPAVQT KTKKTLAKPN
60 70 80 90 100
IRNVVVVDGV RTPFLLSGTS GLLHRTSVPK EVVDYIIFGT VIQEVKTSNV
110 120 130 140 150
AREAALGAGF SDKTPAHTVT MACISANQAM TTGVGLIASG QCDVIVAGGV
160 170 180 190 200
ELMSDVPIRH SRKMRKLMLD LNKAKSMGQR LSLISKFRFN FLAPELPAVS
210 220 230 240 250
EFSTSETMGH SADRLAAAFA VSRLEQDEYA LRSHSLAKKA QDEGLLSDVV
260 270 280 290 300
PFKVPGKDTV TKDNGIRPSS LEQMAKLKPA FIKPYGTVTA ANSSFLTDGA
310 320 330 340 350
SAMLIMAEEK ALAMGYKPKA YLRDFMYVSQ DPKDQLLLGP TYATPKVLEK
360 370 380 390 400
AGLTMNDIDA FEFHEAFSGQ ILANFKAMDS DWFAENYMGR KTKVGLPPLE
410 420 430 440 450
KFNNWGGSLS LGHPFGATGC RLVMAAANRL RKEGGQYGLV AACAAGGQGH

AMIVEAYPK
Length:459
Mass (Da):49,597
Last modified:June 28, 2011 - v1
Checksum:iCED0D1A038DD1512
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010896 Genomic DNA No translation available.
RefSeqiNP_001268441.1, NM_001281512.1
UniGeneiHs.515848

Genome annotation databases

EnsembliENST00000537713; ENSP00000444295; ENSG00000138029
GeneIDi3032
UCSCiuc010ykw.3 human

Similar proteinsi

Entry informationi

Entry nameiF5GZQ3_HUMAN
AccessioniPrimary (citable) accession number: F5GZQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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