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Protein
Submitted name:

Serine/threonine-protein kinase TBK1

Gene

TBK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiF5GZI4.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase TBK1Imported
Gene namesi
Name:TBK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:11584. TBK1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183735.

PTM / Processingi

Proteomic databases

MaxQBiF5GZI4.
PaxDbiF5GZI4.
PeptideAtlasiF5GZI4.

Expressioni

Gene expression databases

BgeeiENSG00000183735.
ExpressionAtlasiF5GZI4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000329967.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 48Protein kinaseInterPro annotationAdd BLAST48

Phylogenomic databases

eggNOGiKOG4250. Eukaryota.
ENOG410XRMU. LUCA.
GeneTreeiENSGT00820000127009.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Fragment.

F5GZI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MREFEVLKKL NHKNIVKLFA IEEETTTRHK VLIMEFCPCG SLYTVLEE
Length:48
Mass (Da):5,712
Last modified:June 28, 2011 - v1
Checksum:i28B3E7E081981E37
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei48Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135279 Genomic DNA. No translation available.
AC136977 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000539810; ENSP00000444428; ENSG00000183735.
UCSCiuc058qjt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135279 Genomic DNA. No translation available.
AC136977 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000329967.

Proteomic databases

MaxQBiF5GZI4.
PaxDbiF5GZI4.
PeptideAtlasiF5GZI4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000539810; ENSP00000444428; ENSG00000183735.
UCSCiuc058qjt.1. human.

Organism-specific databases

HGNCiHGNC:11584. TBK1.
OpenTargetsiENSG00000183735.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4250. Eukaryota.
ENOG410XRMU. LUCA.
GeneTreeiENSGT00820000127009.

Enzyme and pathway databases

SignaLinkiF5GZI4.

Gene expression databases

BgeeiENSG00000183735.
ExpressionAtlasiF5GZI4. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF5GZI4_HUMAN
AccessioniPrimary (citable) accession number: F5GZI4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 15, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.