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Protein
Submitted name:

Centrosomal protein of 57 kDa

Gene

CEP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 57 kDaImported
Gene namesi
Name:CEP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000166037.10
HGNCiHGNC:30794 CEP57

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166037

PTM / Processingi

Proteomic databases

EPDiF5GYW0
MaxQBiF5GYW0
PeptideAtlasiF5GYW0
PRIDEiF5GYW0

Expressioni

Gene expression databases

BgeeiENSG00000166037
ExpressionAtlasiF5GYW0 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiF5GYW0, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliF5GYW0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 217Cep57_CLDInterPro annotationAdd BLAST177
Domaini322 – 394Cep57_MT_bdInterPro annotationAdd BLAST73

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili39 – 73Sequence analysisAdd BLAST35
Coiled coili81 – 133Sequence analysisAdd BLAST53
Coiled coili155 – 210Sequence analysisAdd BLAST56
Coiled coili367 – 423Sequence analysisAdd BLAST57

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IESE Eukaryota
ENOG410XPJC LUCA
GeneTreeiENSGT00530000063695

Family and domain databases

InterProiView protein in InterPro
IPR010597 Centrosomal_protein_57kDa
IPR025913 Cep57_CLD
IPR024957 Cep57_MT-bd_dom
PANTHERiPTHR19336:SF11 PTHR19336:SF11, 1 hit
PfamiView protein in Pfam
PF14073 Cep57_CLD, 1 hit
PF06657 Cep57_MT_bd, 1 hit

Sequencei

Sequence statusi: Complete.

F5GYW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRHSSSPYV VYPSDKPFLN SDLRRSPSKP TLAYPESNSR AIFSALKNLQ
60 70 80 90 100
DKIRRLELER IQAEESVKTL SRETIEYKKV LDEQIQEREN SKNEESKHNQ
110 120 130 140 150
ELTSQLLAAE NKCNLLEKQL EYMRNMIKHA EMERTSVLEK QVSLERERQH
160 170 180 190 200
DQTHVQSQLE KLDLLEQEYN KLTTMQALAE KKMQELEAKL HEEEQERKRM
210 220 230 240 250
QAKAAELQTG LETNRLIFED KATPCVPNAR RIKKKKSKPP EKKSSRNYFG
260 270 280 290 300
AQPHYRLCLG DMPFVAGKST SPSHAVVANV QLVLHLMKQH SKALCNDRVI
310 320 330 340 350
NSIPLAKQVS SRGGKSKKLS VTPPSSNGIN EELSEVLQTL QDEFGQMSFD
360 370 380 390 400
HQQLAKLIQE SPTVELKDKL ECELEALVGR MEAKANQITK VRKYQAQLEK
410 420 430 440 450
QKLEKQKKEL KATKKTLDEE RNSSSRSGIT GTTNKKDFMK LRPGEKRRKN
460 470
LQLLKDMQSI QNSLQSSSLC WDY
Length:473
Mass (Da):54,526
Last modified:June 28, 2011 - v1
Checksum:i050395F21463E850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000537677; ENSP00000441392; ENSG00000166037
UCSCiuc058grh.1 human

Similar proteinsi

Entry informationi

Entry nameiF5GYW0_HUMAN
AccessioniPrimary (citable) accession number: F5GYW0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 25, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health