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Protein
Submitted name:

Centrosomal protein of 57 kDa

Gene

CEP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 57 kDaImported
Gene namesi
Name:CEP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:30794. CEP57.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166037.

PTM / Processingi

Proteomic databases

MaxQBiF5GYW0.
PaxDbiF5GYW0.
PeptideAtlasiF5GYW0.
PRIDEiF5GYW0.

Expressioni

Gene expression databases

BgeeiENSG00000166037.
ExpressionAtlasiF5GYW0. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiF5GYW0. 1 interactor.
STRINGi9606.ENSP00000317902.

Structurei

3D structure databases

ProteinModelPortaliF5GYW0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 217Cep57_CLDInterPro annotationAdd BLAST177
Domaini322 – 394Cep57_MT_bdInterPro annotationAdd BLAST73

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili39 – 73Sequence analysisAdd BLAST35
Coiled coili81 – 133Sequence analysisAdd BLAST53
Coiled coili155 – 210Sequence analysisAdd BLAST56
Coiled coili367 – 423Sequence analysisAdd BLAST57

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IESE. Eukaryota.
ENOG410XPJC. LUCA.
GeneTreeiENSGT00530000063695.

Family and domain databases

InterProiIPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
IPR024957. Cep57_MT-bd_dom.
[Graphical view]
PANTHERiPTHR19336:SF11. PTHR19336:SF11. 1 hit.
PfamiPF14073. Cep57_CLD. 1 hit.
PF06657. Cep57_MT_bd. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5GYW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRHSSSPYV VYPSDKPFLN SDLRRSPSKP TLAYPESNSR AIFSALKNLQ
60 70 80 90 100
DKIRRLELER IQAEESVKTL SRETIEYKKV LDEQIQEREN SKNEESKHNQ
110 120 130 140 150
ELTSQLLAAE NKCNLLEKQL EYMRNMIKHA EMERTSVLEK QVSLERERQH
160 170 180 190 200
DQTHVQSQLE KLDLLEQEYN KLTTMQALAE KKMQELEAKL HEEEQERKRM
210 220 230 240 250
QAKAAELQTG LETNRLIFED KATPCVPNAR RIKKKKSKPP EKKSSRNYFG
260 270 280 290 300
AQPHYRLCLG DMPFVAGKST SPSHAVVANV QLVLHLMKQH SKALCNDRVI
310 320 330 340 350
NSIPLAKQVS SRGGKSKKLS VTPPSSNGIN EELSEVLQTL QDEFGQMSFD
360 370 380 390 400
HQQLAKLIQE SPTVELKDKL ECELEALVGR MEAKANQITK VRKYQAQLEK
410 420 430 440 450
QKLEKQKKEL KATKKTLDEE RNSSSRSGIT GTTNKKDFMK LRPGEKRRKN
460 470
LQLLKDMQSI QNSLQSSSLC WDY
Length:473
Mass (Da):54,526
Last modified:June 28, 2011 - v1
Checksum:i050395F21463E850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000537677; ENSP00000441392; ENSG00000166037.
UCSCiuc058grh.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5GYW0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF5GYW0. 1 interactor.
STRINGi9606.ENSP00000317902.

Proteomic databases

MaxQBiF5GYW0.
PaxDbiF5GYW0.
PeptideAtlasiF5GYW0.
PRIDEiF5GYW0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000537677; ENSP00000441392; ENSG00000166037.
UCSCiuc058grh.1. human.

Organism-specific databases

HGNCiHGNC:30794. CEP57.
OpenTargetsiENSG00000166037.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IESE. Eukaryota.
ENOG410XPJC. LUCA.
GeneTreeiENSGT00530000063695.

Gene expression databases

BgeeiENSG00000166037.
ExpressionAtlasiF5GYW0. baseline and differential.

Family and domain databases

InterProiIPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
IPR024957. Cep57_MT-bd_dom.
[Graphical view]
PANTHERiPTHR19336:SF11. PTHR19336:SF11. 1 hit.
PfamiPF14073. Cep57_CLD. 1 hit.
PF06657. Cep57_MT_bd. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5GYW0_HUMAN
AccessioniPrimary (citable) accession number: F5GYW0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.