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F5GYW0

- F5GYW0_HUMAN

UniProt

F5GYW0 - F5GYW0_HUMAN

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Protein
Submitted name: Centrosomal protein of 57 kDa
Gene
CEP57
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. microtubule anchoring Source: InterPro
  2. protein homooligomerization Source: Ensembl
  3. protein import into nucleus, translocation Source: Ensembl
  4. spermatid development Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 57 kDaImported
Gene namesi
Name:CEP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:30794. CEP57.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: Ensembl
  2. cytoplasm Source: HPA
  3. microtubule cytoskeleton Source: HPA
  4. nucleus Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiF5GYW0.

Expressioni

Gene expression databases

ArrayExpressiF5GYW0.
BgeeiF5GYW0.

Structurei

3D structure databases

ProteinModelPortaliF5GYW0.
SMRiF5GYW0. Positions 328-401.

Family & Domainsi

Phylogenomic databases

OrthoDBiEOG7RBZ92.

Family and domain databases

InterProiIPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
IPR024957. Cep57_MT-bd_dom.
[Graphical view]
PANTHERiPTHR19336. PTHR19336. 1 hit.
PfamiPF14073. Cep57_CLD. 1 hit.
PF06657. Cep57_MT_bd. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5GYW0-1 [UniParc]FASTAAdd to Basket

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MVRHSSSPYV VYPSDKPFLN SDLRRSPSKP TLAYPESNSR AIFSALKNLQ    50
DKIRRLELER IQAEESVKTL SRETIEYKKV LDEQIQEREN SKNEESKHNQ 100
ELTSQLLAAE NKCNLLEKQL EYMRNMIKHA EMERTSVLEK QVSLERERQH 150
DQTHVQSQLE KLDLLEQEYN KLTTMQALAE KKMQELEAKL HEEEQERKRM 200
QAKAAELQTG LETNRLIFED KATPCVPNAR RIKKKKSKPP EKKSSRNYFG 250
AQPHYRLCLG DMPFVAGKST SPSHAVVANV QLVLHLMKQH SKALCNDRVI 300
NSIPLAKQVS SRGGKSKKLS VTPPSSNGIN EELSEVLQTL QDEFGQMSFD 350
HQQLAKLIQE SPTVELKDKL ECELEALVGR MEAKANQITK VRKYQAQLEK 400
QKLEKQKKEL KATKKTLDEE RNSSSRSGIT GTTNKKDFMK LRPGEKRRKN 450
LQLLKDMQSI QNSLQSSSLC WDY 473
Length:473
Mass (Da):54,526
Last modified:June 28, 2011 - v1
Checksum:i050395F21463E850
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP001877 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000537677; ENSP00000441392; ENSG00000166037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP001877 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F5GYW0.
SMRi F5GYW0. Positions 328-401.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F5GYW0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000537677 ; ENSP00000441392 ; ENSG00000166037 .

Organism-specific databases

HGNCi HGNC:30794. CEP57.
GenAtlasi Search...

Phylogenomic databases

OrthoDBi EOG7RBZ92.

Miscellaneous databases

GenomeRNAii 9702.
NextBioi 35507708.

Gene expression databases

ArrayExpressi F5GYW0.
Bgeei F5GYW0.

Family and domain databases

InterProi IPR010597. Centrosomal_protein_57kDa.
IPR025913. Cep57_CLD.
IPR024957. Cep57_MT-bd_dom.
[Graphical view ]
PANTHERi PTHR19336. PTHR19336. 1 hit.
Pfami PF14073. Cep57_CLD. 1 hit.
PF06657. Cep57_MT_bd. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5GYW0_HUMAN
AccessioniPrimary (citable) accession number: F5GYW0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 3, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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