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F5GYW0

- F5GYW0_HUMAN

UniProt

F5GYW0 - F5GYW0_HUMAN

Protein
Submitted name:

Centrosomal protein of 57 kDa

Gene

CEP57

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. microtubule anchoring Source: InterPro
    2. protein homooligomerization Source: Ensembl
    3. protein import into nucleus, translocation Source: Ensembl
    4. spermatid development Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Centrosomal protein of 57 kDaImported
    Gene namesi
    Name:CEP57Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:30794. CEP57.

    Subcellular locationi

    GO - Cellular componenti

    1. centrosome Source: Ensembl
    2. cytoplasm Source: HPA
    3. microtubule cytoskeleton Source: HPA
    4. nucleus Source: HPA

    PTM / Processingi

    Proteomic databases

    PRIDEiF5GYW0.

    Expressioni

    Gene expression databases

    ArrayExpressiF5GYW0.
    BgeeiF5GYW0.

    Structurei

    3D structure databases

    ProteinModelPortaliF5GYW0.
    SMRiF5GYW0. Positions 328-401.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OrthoDBiEOG7RBZ92.

    Family and domain databases

    InterProiIPR010597. Centrosomal_protein_57kDa.
    IPR025913. Cep57_CLD.
    IPR024957. Cep57_MT-bd_dom.
    [Graphical view]
    PANTHERiPTHR19336. PTHR19336. 1 hit.
    PfamiPF14073. Cep57_CLD. 1 hit.
    PF06657. Cep57_MT_bd. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F5GYW0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRHSSSPYV VYPSDKPFLN SDLRRSPSKP TLAYPESNSR AIFSALKNLQ    50
    DKIRRLELER IQAEESVKTL SRETIEYKKV LDEQIQEREN SKNEESKHNQ 100
    ELTSQLLAAE NKCNLLEKQL EYMRNMIKHA EMERTSVLEK QVSLERERQH 150
    DQTHVQSQLE KLDLLEQEYN KLTTMQALAE KKMQELEAKL HEEEQERKRM 200
    QAKAAELQTG LETNRLIFED KATPCVPNAR RIKKKKSKPP EKKSSRNYFG 250
    AQPHYRLCLG DMPFVAGKST SPSHAVVANV QLVLHLMKQH SKALCNDRVI 300
    NSIPLAKQVS SRGGKSKKLS VTPPSSNGIN EELSEVLQTL QDEFGQMSFD 350
    HQQLAKLIQE SPTVELKDKL ECELEALVGR MEAKANQITK VRKYQAQLEK 400
    QKLEKQKKEL KATKKTLDEE RNSSSRSGIT GTTNKKDFMK LRPGEKRRKN 450
    LQLLKDMQSI QNSLQSSSLC WDY 473
    Length:473
    Mass (Da):54,526
    Last modified:June 28, 2011 - v1
    Checksum:i050395F21463E850
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001877 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000537677; ENSP00000441392; ENSG00000166037.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001877 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F5GYW0.
    SMRi F5GYW0. Positions 328-401.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F5GYW0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000537677 ; ENSP00000441392 ; ENSG00000166037 .

    Organism-specific databases

    HGNCi HGNC:30794. CEP57.
    GenAtlasi Search...

    Phylogenomic databases

    OrthoDBi EOG7RBZ92.

    Miscellaneous databases

    NextBioi 35507708.

    Gene expression databases

    ArrayExpressi F5GYW0.
    Bgeei F5GYW0.

    Family and domain databases

    InterProi IPR010597. Centrosomal_protein_57kDa.
    IPR025913. Cep57_CLD.
    IPR024957. Cep57_MT-bd_dom.
    [Graphical view ]
    PANTHERi PTHR19336. PTHR19336. 1 hit.
    Pfami PF14073. Cep57_CLD. 1 hit.
    PF06657. Cep57_MT_bd. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF5GYW0_HUMAN
    AccessioniPrimary (citable) accession number: F5GYW0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3