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Protein
Submitted name:

Homeobox protein Meis1

Gene

MEIS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi207 – 269HomeoboxPROSITE-ProRule annotationAdd BLAST63

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox protein Meis1Imported
Gene namesi
Name:MEIS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000143995.19.
HGNCiHGNC:7000. MEIS1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143995.

PTM / Processingi

Proteomic databases

MaxQBiF5GYS8.
PaxDbiF5GYS8.
PeptideAtlasiF5GYS8.
PRIDEiF5GYS8.

Expressioni

Gene expression databases

BgeeiENSG00000143995.
ExpressionAtlasiF5GYS8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5GYS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini205 – 268HomeoboxInterPro annotationAdd BLAST64

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
GeneTreeiENSGT00550000074260.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR032453. PKNOX/Meis_N.
PfamiView protein in Pfam
PF05920. Homeobox_KN. 1 hit.
PF16493. Meis_PKNOX_N. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F5GYS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQGLRLQGS RRKGRHPLFP LLALIFEKCE LATCTPREPG VAGGDVCSSE
60 70 80 90 100
SFNEDIAVFA KQIRAEKPLF SSNPELDNLM IQAIQVLRFH LLELEKVHEL
110 120 130 140 150
CDNFCHRYIS CLKGKMPIDL VIDDREGGSK SDSEDITRSA NLTDQPSWNR
160 170 180 190 200
DHDDTASTRS GGTPGPSSGG HTSHSGDNSS EQGDGLDNSV ASPSTGDDDD
210 220 230 240 250
PDKDKKRHKK RGIFPKVATN IMRAWLFQHL THPYPSEEQK KQLAQDTGLT
260 270 280 290 300
ILQVNNWFIN ARRRIVQPMI DQSNRAVSQG TPYNPDGQPM GGFVMDGQQH
310 320
MGIRAPGPMS GMGMNMGMEG QWHYM
Length:325
Mass (Da):36,013
Last modified:June 28, 2011 - v1
Checksum:iB56394B4E32B6D73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007392 Genomic DNA. No translation available.
AC092669 Genomic DNA. No translation available.
AC093641 Genomic DNA. No translation available.
RefSeqiXP_005264382.1. XM_005264325.4.
UniGeneiHs.526754.
Hs.603755.

Genome annotation databases

EnsembliENST00000495021; ENSP00000440571; ENSG00000143995.
GeneIDi4211.
UCSCiuc010yqi.2. human.

Similar proteinsi

Entry informationi

Entry nameiF5GYS8_HUMAN
AccessioniPrimary (citable) accession number: F5GYS8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 27, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported