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F5GYS8

- F5GYS8_HUMAN

UniProt

F5GYS8 - F5GYS8_HUMAN

Protein
Submitted name:

Homeobox protein Meis1

Gene

MEIS1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Homeobox protein Meis1Imported
    Gene namesi
    Name:MEIS1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:7000. MEIS1.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiF5GYS8.
    BgeeiF5GYS8.

    Structurei

    3D structure databases

    ProteinModelPortaliF5GYS8.
    SMRiF5GYS8. Positions 214-269.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    HomeoboxUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK15613.
    OMAiVSQGAPY.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR001356. Homeobox_dom.
    IPR008422. Homeobox_KN_domain.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF05920. Homeobox_KN. 1 hit.
    [Graphical view]
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F5GYS8-1 [UniParc]FASTAAdd to Basket

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    MAQGLRLQGS RRKGRHPLFP LLALIFEKCE LATCTPREPG VAGGDVCSSE    50
    SFNEDIAVFA KQIRAEKPLF SSNPELDNLM IQAIQVLRFH LLELEKVHEL 100
    CDNFCHRYIS CLKGKMPIDL VIDDREGGSK SDSEDITRSA NLTDQPSWNR 150
    DHDDTASTRS GGTPGPSSGG HTSHSGDNSS EQGDGLDNSV ASPSTGDDDD 200
    PDKDKKRHKK RGIFPKVATN IMRAWLFQHL THPYPSEEQK KQLAQDTGLT 250
    ILQVNNWFIN ARRRIVQPMI DQSNRAVSQG TPYNPDGQPM GGFVMDGQQH 300
    MGIRAPGPMS GMGMNMGMEG QWHYM 325
    Length:325
    Mass (Da):36,013
    Last modified:June 28, 2011 - v1
    Checksum:iB56394B4E32B6D73
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007392 Genomic DNA. No translation available.
    AC092669 Genomic DNA. No translation available.
    AC093641 Genomic DNA. No translation available.
    RefSeqiXP_005264382.1. XM_005264325.2.
    UniGeneiHs.526754.
    Hs.603755.

    Genome annotation databases

    EnsembliENST00000495021; ENSP00000440571; ENSG00000143995.
    GeneIDi4211.
    KEGGihsa:4211.
    UCSCiuc010yqi.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007392 Genomic DNA. No translation available.
    AC092669 Genomic DNA. No translation available.
    AC093641 Genomic DNA. No translation available.
    RefSeqi XP_005264382.1. XM_005264325.2.
    UniGenei Hs.526754.
    Hs.603755.

    3D structure databases

    ProteinModelPortali F5GYS8.
    SMRi F5GYS8. Positions 214-269.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000495021 ; ENSP00000440571 ; ENSG00000143995 .
    GeneIDi 4211.
    KEGGi hsa:4211.
    UCSCi uc010yqi.2. human.

    Organism-specific databases

    CTDi 4211.
    HGNCi HGNC:7000. MEIS1.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K15613.
    OMAi VSQGAPY.

    Miscellaneous databases

    ChiTaRSi MEIS1. human.
    GenomeRNAii 4211.
    NextBioi 35507690.

    Gene expression databases

    ArrayExpressi F5GYS8.
    Bgeei F5GYS8.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR001356. Homeobox_dom.
    IPR008422. Homeobox_KN_domain.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF05920. Homeobox_KN. 1 hit.
    [Graphical view ]
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF5GYS8_HUMAN
    AccessioniPrimary (citable) accession number: F5GYS8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3