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Protein
Submitted name:

SH2B adapter protein 3

Gene

SH2B3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF5GYM4

Names & Taxonomyi

Protein namesi
Submitted name:
SH2B adapter protein 3Imported
Gene namesi
Name:SH2B3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111252.10
HGNCiHGNC:29605 SH2B3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111252

PTM / Processingi

Proteomic databases

MaxQBiF5GYM4
PeptideAtlasiF5GYM4
PRIDEiF5GYM4

Expressioni

Gene expression databases

BgeeiENSG00000111252
ExpressionAtlasiF5GYM4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5GYM4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 260SH2InterPro annotationAdd BLAST99

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IFCS Eukaryota
ENOG410YMBM LUCA
GeneTreeiENSGT00530000063355

Family and domain databases

CDDicd10412 SH2_SH2B3, 1 hit
Gene3Di2.30.29.30, 1 hit
3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR030523 SH2B
IPR030522 SH2B3
IPR035059 SH2B3_SH2
PANTHERiPTHR10872 PTHR10872, 1 hit
PTHR10872:SF1 PTHR10872:SF1, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SUPFAMiSSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit

Sequencei

Sequence statusi: Complete.

F5GYM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFPVLCRGW RRTWPGCASW LGAPPPQKPL LSPLLLNHRS SKSSRPKLQA
60 70 80 90 100
ACSSIQEVRW CTRLEMPDNL YTFVLKVKDR TDIIFEVGDE QQLNSWMAEL
110 120 130 140 150
SECTGRGLES TEAEMHIPSA LEPSTSSSPR GSTDSLNQGA SPGGLLDPAC
160 170 180 190 200
QKTDHFLSCY PWFHGPISRV KAAQLVQLQG PDAHGVFLVR QSETRRGEYV
210 220 230 240 250
LTFNFQGIAK HLRLSLTERG QCRVQHLHFP SVVDMLHHFQ RSPIPLECGA
260 270 280 290 300
ACDVRLSSYV VVVSQPPGSC NTVLFPFSLP HWDSESLPHW GSELGLPHLS
310 320 330 340 350
SSGCPRGLSP EGLPGRSSPP EQIFHLVPSP EELANSLQHL EHEPVNRARD
360 370
SDYEMDSSSR SHLRAIDNQY TPL
Length:373
Mass (Da):41,449
Last modified:June 28, 2011 - v1
Checksum:i5D8D8631D492A527
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002395 Genomic DNA No translation available.
AC005805 Genomic DNA No translation available.
RefSeqiNP_001278353.1, NM_001291424.1
UniGeneiHs.506784

Genome annotation databases

EnsembliENST00000538307; ENSP00000440597; ENSG00000111252
GeneIDi10019
UCSCiuc010syg.3 human

Similar proteinsi

Entry informationi

Entry nameiF5GYM4_HUMAN
AccessioniPrimary (citable) accession number: F5GYM4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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