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Protein
Submitted name:

ATP-dependent RNA helicase DDX24

Gene

DDX24

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHelicaseUniRule annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase DDX24Imported
Gene namesi
Name:DDX24Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000089737.15
HGNCiHGNC:13266 DDX24

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089737

PTM / Processingi

Proteomic databases

MaxQBiF5GYL3
PeptideAtlasiF5GYL3
PRIDEiF5GYL3

Expressioni

Gene expression databases

BgeeiENSG00000089737
ExpressionAtlasiF5GYL3 baseline and differential

Structurei

3D structure databases

SMRiF5GYL3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini141 – 278Helicase ATP-bindingInterPro annotationAdd BLAST138
Domaini328 – 473Helicase C-terminalInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0347 Eukaryota
ENOG410XS03 LUCA
GeneTreeiENSGT00550000074847

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequencei

Sequence statusi: Complete.

F5GYL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIHAVLQWQK RNAAPPPSNT EAPPGETRTE AGAETRSPGK AEAESDALPD
60 70 80 90 100
DTVIESEALP SDIAAEARAK TGGTVSDQAL LFGDDDAGEG PSSLIREKPV
110 120 130 140 150
PKQNENEEEN LDKEQTGNLK QELDDKSATC KAYPKRPLLG LVLTPTRELA
160 170 180 190 200
VQVKQHIDAV ARFTGIKTAI LVGGMSTQKQ QRMLNRRPEI VVATPGRLWE
210 220 230 240 250
LIKEKHYHLR NLRQLRCLVV DEADRMVEKG HFAELSQLLE MLNDSQYNPK
260 270 280 290 300
RQTLVFSATL TLVHQAPARI LHKKHTKKMD KTAKLDLLMQ KIGMRGKPKV
310 320 330 340 350
IDLTRNEATV ETLTETKIHC ETDEKDFYLY YFLMQYPGRS LVFANSISCI
360 370 380 390 400
KRLSGLLKVL DIMPLTLHAC MHQKQRLRNL EQFARLEDCV LLATDVAARG
410 420 430 440 450
LDIPKVQHVI HYQVPRTSEI YVHRSGRTAR ATNEGLSLML IGPEDVINFK
460 470 480 490 500
KIYKTLKKDE DIPLFPVQTK YMDVVKERIR LARQIEKSEY RNFQACLHNS
510 520 530 540 550
WIEQAAAALE IELEEDMYKG GKADQQEERR RQKQMKVLKK ELRHLLSQPL
560 570 580 590 600
FTESQKTKYP TQSGKPPLLV SAPSKSESAL SCLSKQKKKK TKKPKEPQPE

QPQPSTSAN
Length:609
Mass (Da):68,973
Last modified:June 28, 2011 - v1
Checksum:iBCDED88BD9A4AA9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079302 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000544005; ENSP00000440623; ENSG00000089737
ENST00000626330; ENSP00000486353; ENSG00000273761
UCSCiuc010twr.3 human

Similar proteinsi

Entry informationi

Entry nameiF5GYL3_HUMAN
AccessioniPrimary (citable) accession number: F5GYL3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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