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Protein
Submitted name:

ATP-dependent RNA helicase DDX24

Gene

DDX24

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HelicaseUniRule annotation, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase DDX24Imported
Gene namesi
Name:DDX24Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:13266. DDX24.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089737.
ENSG00000273761.

PTM / Processingi

Proteomic databases

MaxQBiF5GYL3.
PeptideAtlasiF5GYL3.
PRIDEiF5GYL3.

Expressioni

Gene expression databases

BgeeiENSG00000089737.
ExpressionAtlasiF5GYL3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000328690.

Structurei

3D structure databases

ProteinModelPortaliF5GYL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini141 – 278Helicase ATP-bindingInterPro annotationAdd BLAST138
Domaini328 – 473Helicase C-terminalInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0347. Eukaryota.
ENOG410XS03. LUCA.
GeneTreeiENSGT00550000074847.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5GYL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIHAVLQWQK RNAAPPPSNT EAPPGETRTE AGAETRSPGK AEAESDALPD
60 70 80 90 100
DTVIESEALP SDIAAEARAK TGGTVSDQAL LFGDDDAGEG PSSLIREKPV
110 120 130 140 150
PKQNENEEEN LDKEQTGNLK QELDDKSATC KAYPKRPLLG LVLTPTRELA
160 170 180 190 200
VQVKQHIDAV ARFTGIKTAI LVGGMSTQKQ QRMLNRRPEI VVATPGRLWE
210 220 230 240 250
LIKEKHYHLR NLRQLRCLVV DEADRMVEKG HFAELSQLLE MLNDSQYNPK
260 270 280 290 300
RQTLVFSATL TLVHQAPARI LHKKHTKKMD KTAKLDLLMQ KIGMRGKPKV
310 320 330 340 350
IDLTRNEATV ETLTETKIHC ETDEKDFYLY YFLMQYPGRS LVFANSISCI
360 370 380 390 400
KRLSGLLKVL DIMPLTLHAC MHQKQRLRNL EQFARLEDCV LLATDVAARG
410 420 430 440 450
LDIPKVQHVI HYQVPRTSEI YVHRSGRTAR ATNEGLSLML IGPEDVINFK
460 470 480 490 500
KIYKTLKKDE DIPLFPVQTK YMDVVKERIR LARQIEKSEY RNFQACLHNS
510 520 530 540 550
WIEQAAAALE IELEEDMYKG GKADQQEERR RQKQMKVLKK ELRHLLSQPL
560 570 580 590 600
FTESQKTKYP TQSGKPPLLV SAPSKSESAL SCLSKQKKKK TKKPKEPQPE

QPQPSTSAN
Length:609
Mass (Da):68,973
Last modified:June 28, 2011 - v1
Checksum:iBCDED88BD9A4AA9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079302 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000544005; ENSP00000440623; ENSG00000089737.
ENST00000626330; ENSP00000486353; ENSG00000273761.
UCSCiuc010twr.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079302 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5GYL3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000328690.

Proteomic databases

MaxQBiF5GYL3.
PeptideAtlasiF5GYL3.
PRIDEiF5GYL3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000544005; ENSP00000440623; ENSG00000089737.
ENST00000626330; ENSP00000486353; ENSG00000273761.
UCSCiuc010twr.3. human.

Organism-specific databases

HGNCiHGNC:13266. DDX24.
OpenTargetsiENSG00000089737.
ENSG00000273761.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0347. Eukaryota.
ENOG410XS03. LUCA.
GeneTreeiENSGT00550000074847.

Miscellaneous databases

ChiTaRSiDDX24. human.

Gene expression databases

BgeeiENSG00000089737.
ExpressionAtlasiF5GYL3. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5GYL3_HUMAN
AccessioniPrimary (citable) accession number: F5GYL3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.