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Protein
Submitted name:

Activin receptor type-1

Gene

ACVR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Activin receptor type-1Imported
Gene namesi
Name:ACVR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:171. ACVR1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 7351Sequence analysisPRO_5006725563Add
BLAST

Proteomic databases

PaxDbiF5GY91.

Expressioni

Gene expression databases

BgeeiENSG00000115170.
ExpressionAtlasiF5GY91. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263640.

Structurei

3D structure databases

ProteinModelPortaliF5GY91.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2052. Eukaryota.
ENOG410XQT0. LUCA.
GeneTreeiENSGT00760000118876.

Family and domain databases

InterProiIPR000333. TGFB_receptor.
[Graphical view]
PANTHERiPTHR23255. PTHR23255. 1 hit.

Sequencei

Sequence statusi: Fragment.

F5GY91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDGVMILPV LIMIALPSPS MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG
60 70
QQCFSSLSIN DGFHVYQKGC FQV
Length:73
Mass (Da):8,055
Last modified:February 17, 2016 - v7
Checksum:i93E665B3BADEFB8C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei73 – 731Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013731 Genomic DNA. No translation available.
AC019186 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000539637; ENSP00000440091; ENSG00000115170.
UCSCiuc061otw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013731 Genomic DNA. No translation available.
AC019186 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF5GY91.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263640.

Proteomic databases

PaxDbiF5GY91.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000539637; ENSP00000440091; ENSG00000115170.
UCSCiuc061otw.1. human.

Organism-specific databases

HGNCiHGNC:171. ACVR1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2052. Eukaryota.
ENOG410XQT0. LUCA.
GeneTreeiENSGT00760000118876.

Miscellaneous databases

ChiTaRSiACVR1. human.

Gene expression databases

BgeeiENSG00000115170.
ExpressionAtlasiF5GY91. baseline and differential.

Family and domain databases

InterProiIPR000333. TGFB_receptor.
[Graphical view]
PANTHERiPTHR23255. PTHR23255. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF5GY91_HUMAN
AccessioniPrimary (citable) accession number: F5GY91
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: February 17, 2016
Last modified: September 7, 2016
This is version 36 of the entry and version 7 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.