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F5GY91

- F5GY91_HUMAN

UniProt

F5GY91 - F5GY91_HUMAN

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Protein
Submitted name:

Activin receptor type-1

Gene

ACVR1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. activin receptor activity, type I Source: Ensembl
  2. ATP binding Source: InterPro
  3. receptor signaling protein serine/threonine kinase activity Source: Ensembl
  4. transforming growth factor beta receptor activity, type I Source: Ensembl

GO - Biological processi

  1. acute inflammatory response Source: Ensembl
  2. cellular response to glucocorticoid stimulus Source: Ensembl
  3. determination of left/right symmetry Source: Ensembl
  4. gastrulation with mouth forming second Source: Ensembl
  5. germ cell development Source: Ensembl
  6. heart development Source: Ensembl
  7. in utero embryonic development Source: Ensembl
  8. mesoderm formation Source: Ensembl
  9. neural crest cell migration Source: Ensembl
  10. patterning of blood vessels Source: Ensembl
  11. pharyngeal system development Source: Ensembl
  12. regulation of skeletal muscle tissue development Source: Ensembl
  13. smooth muscle cell differentiation Source: Ensembl
  14. transforming growth factor beta receptor signaling pathway Source: Ensembl
  15. urogenital system development Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Activin receptor type-1Imported
Gene namesi
Name:ACVR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:171. ACVR1.

Subcellular locationi

GO - Cellular componenti

  1. activin receptor complex Source: Ensembl
  2. apical part of cell Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF5GY91.
ExpressionAtlasiF5GY91. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118876.

Family and domain databases

InterProiIPR000333. TGFB_receptor.
[Graphical view]
PANTHERiPTHR23255. PTHR23255. 1 hit.

Sequencei

Sequence statusi: Fragment.

F5GY91-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVDGVMILPV LIMIALPSPS MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG
60 70
QQCFSSLSIN DGFHVYQKGC FQV
Length:73
Mass (Da):8,055
Last modified:October 29, 2014 - v3
Checksum:i93E665B3BADEFB8C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei73 – 731Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013731 Genomic DNA. No translation available.
AC019186 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000539637; ENSP00000440091; ENSG00000115170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013731 Genomic DNA. No translation available.
AC019186 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi F5GY91.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000539637 ; ENSP00000440091 ; ENSG00000115170 .

Organism-specific databases

HGNCi HGNC:171. ACVR1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118876.

Miscellaneous databases

ChiTaRSi ACVR1. human.
NextBioi 35507575.

Gene expression databases

Bgeei F5GY91.
ExpressionAtlasi F5GY91. baseline and differential.

Family and domain databases

InterProi IPR000333. TGFB_receptor.
[Graphical view ]
PANTHERi PTHR23255. PTHR23255. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5GY91_HUMAN
AccessioniPrimary (citable) accession number: F5GY91
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: October 29, 2014
Last modified: November 26, 2014
This is version 23 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3