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F5GY91

- F5GY91_HUMAN

UniProt

F5GY91 - F5GY91_HUMAN

Protein
Submitted name:

Activin receptor type-1

Gene

ACVR1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. activin receptor activity, type I Source: Ensembl
    2. ATP binding Source: InterPro
    3. receptor signaling protein serine/threonine kinase activity Source: Ensembl
    4. transforming growth factor beta receptor activity, type I Source: Ensembl

    GO - Biological processi

    1. acute inflammatory response Source: Ensembl
    2. cellular response to glucocorticoid stimulus Source: Ensembl
    3. determination of left/right symmetry Source: Ensembl
    4. gastrulation with mouth forming second Source: Ensembl
    5. germ cell development Source: Ensembl
    6. heart development Source: Ensembl
    7. in utero embryonic development Source: Ensembl
    8. mesoderm formation Source: Ensembl
    9. neural crest cell migration Source: Ensembl
    10. patterning of blood vessels Source: Ensembl
    11. pharyngeal system development Source: Ensembl
    12. regulation of skeletal muscle tissue development Source: Ensembl
    13. smooth muscle cell differentiation Source: Ensembl
    14. transforming growth factor beta receptor signaling pathway Source: Ensembl
    15. urogenital system development Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Activin receptor type-1Imported
    Gene namesi
    Name:ACVR1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:171. ACVR1.

    Subcellular locationi

    GO - Cellular componenti

    1. activin receptor complex Source: Ensembl
    2. apical part of cell Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiF5GY91.
    BgeeiF5GY91.

    Family & Domainsi

    Family and domain databases

    InterProiIPR000333. TGFB_receptor.
    [Graphical view]
    PANTHERiPTHR23255. PTHR23255. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    F5GY91-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVDGVMILPV LIMIALPSPS MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG   50
    QQCFSSLSIN DGFHVYQKGC FQ 72
    Length:72
    Mass (Da):7,956
    Last modified:May 14, 2014 - v2
    Checksum:i1665B3BADEFB8CAB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei72 – 721Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC013731 Genomic DNA. No translation available.
    AC019186 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000539637; ENSP00000440091; ENSG00000115170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC013731 Genomic DNA. No translation available.
    AC019186 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000539637 ; ENSP00000440091 ; ENSG00000115170 .

    Organism-specific databases

    HGNCi HGNC:171. ACVR1.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35507575.

    Gene expression databases

    ArrayExpressi F5GY91.
    Bgeei F5GY91.

    Family and domain databases

    InterProi IPR000333. TGFB_receptor.
    [Graphical view ]
    PANTHERi PTHR23255. PTHR23255. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF5GY91_HUMAN
    AccessioniPrimary (citable) accession number: F5GY91
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 21 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3