Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Tyrosine-protein phosphatase non-receptor type 6

Gene

PTPN6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiF5GY79

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine-protein phosphatase non-receptor type 6Imported
Gene namesi
Name:PTPN6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111679.16
HGNCiHGNC:9658 PTPN6

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111679

PTM / Processingi

Proteomic databases

MaxQBiF5GY79
PeptideAtlasiF5GY79
PRIDEiF5GY79

Expressioni

Gene expression databases

BgeeiENSG00000111679
ExpressionAtlasiF5GY79 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5GY79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 59SH2InterPro annotationAdd BLAST59
Domaini69 – 144SH2InterPro annotationAdd BLAST76

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0790 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00910000144001

Family and domain databases

Gene3Di3.30.505.102 hits
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
PfamiView protein in Pfam
PF00017 SH2, 2 hits
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SUPFAMiSSF55550 SSF55550, 2 hits
PROSITEiView protein in PROSITE
PS50001 SH2, 2 hits

Sequencei

Sequence statusi: Fragment.

F5GY79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRVGDQVTH IRIQNSGDFY DLYGGEKFAT LTELVEYYTQ QQGVLQDRDG
60 70 80 90 100
TIIHLKYPLN CSDPTSERWY HGHMSGGQAE TLLQAKGEPW TFLVRESLSQ
110 120 130 140
PGDFVLSVLS DQPKAGPGSP LRVTHIKVMC EGGRYTVGGL ETFD
Length:144
Mass (Da):16,066
Last modified:June 28, 2011 - v1
Checksum:i49AB3BDEBB11931C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei144Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47924 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000542462; ENSP00000440114; ENSG00000111679
UCSCiuc058kop.1 human

Similar proteinsi

Entry informationi

Entry nameiF5GY79_HUMAN
AccessioniPrimary (citable) accession number: F5GY79
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 25, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported