F5GXH4 (F5GXH4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
N-acetylserotonin O-methyltransferase-like protein Ensembl ENSP00000446410

Gene names

Name:

ASMTL Ensembl ENSP00000446410

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000446410

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	563 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000446410

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA
Molecular_function	O-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F5GXH4 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 5AC40CB68911EF40	FASTA	563	62,443
	10 20 30 40 50 60 METAKQKALE VANRLYQKDL RAPDVVIGAD TIVTVGGLIL EKPVDKQDAY RMLSRLSGRE 70 80 90 100 110 120 HSVFTGVAIV HCSSKDHQLD TRVSEFYEET KVKFSELSEE LLWEYVHSGE PMDKAGGYGI 130 140 150 160 170 180 QALGGMLVES VHGDFLNVVG FPLNHFCKQL VKLYYPPRPE DLRRSVKHDS IPAADTFEDL 190 200 210 220 230 240 SDVEGGGSEP TQRDAGSRDE KAEAGEAGQA TAEAECHRTR ETLPPFPTRL LELIEGFMLS 250 260 270 280 290 300 KGLLTACKLK VFDLLKDEAP QKAADIASKV DASACGMERL LDICAAMGLL EKTEQGYSNT 310 320 330 340 350 360 ETANVYLASD GEYSLHGFIM HNNDLTWNLF TYLEFAIREG TNQHHRALGK KAEDLFQDAY 370 380 390 400 410 420 YQSPETRLRF MRAMHGMTKL TACQVATAFN LSRFSSACDV GGCTGALARE LAREYPRMQV 430 440 450 460 470 480 TVFDLPDIIE LAAHFQPPGP QAVQIHFAAG DFFRDPLPSA ELYVLCRILH DWPDDKVHKL 490 500 510 520 530 540 LSRVAESCKP GAGLLLVETL LDEEKRVAQR ALMQSLNMLV QTEGKERSLG EYQCLLELHG 550 560 FHQVQVVHLG GVLDAILATK VAP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R. Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL683870 Genomic DNA. No translation available.
IPI	IPI00956483.
RefSeq	NP_001166944.1. NM_001173473.1.
UniGene	Hs.533514.
3D structure databases
ProteinModelPortal	F5GXH4.
SMR	F5GXH4. Positions 1-155, 229-560.
ModBase	Search...
Protocols and materials databases
DNASU	8623.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000534940; ENSP00000446410; ENSG00000169093.
GeneID	8623.
KEGG	hsa:8623.
Organism-specific databases
CTD	8623.
HGNC	HGNC:751. ASMTL.
GenAtlas	Search...
Gene expression databases
ArrayExpress	F5GXH4.
Bgee	F5GXH4.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR025772. ASMT-like. IPR003697. Maf. IPR001077. O_MeTrfase_2. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF02545. Maf. 1 hit. PF00891. Methyltransf_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00172. maf. 1 hit.
PROSITE	PS51586. SAM_MT_ASMTL_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	8623.
NextBio	32321.

Entry information

Entry name

F5GXH4_HUMAN

Accession

Primary (citable) accession number: F5GXH4

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.