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Protein
Submitted name:

Adenosine deaminase

Gene

ADA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adenosine deaminaseImported
Submitted name:
Adenosine deaminase isoform 2Imported
Gene namesi
Name:ADAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000196839.12
HGNCiHGNC:186 ADA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196839

PTM / Processingi

Proteomic databases

MaxQBiF5GWI4
PeptideAtlasiF5GWI4
PRIDEiF5GWI4

Expressioni

Gene expression databases

BgeeiENSG00000196839
ExpressionAtlasiF5GWI4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 201A_deaminaseInterPro annotationAdd BLAST193
Domaini202 – 321A_deaminaseInterPro annotationAdd BLAST120

Phylogenomic databases

GeneTreeiENSGT00730000111151

Family and domain databases

CDDicd01320 ADA, 1 hit
InterProiView protein in InterPro
IPR006650 A/AMP_deam_AS
IPR001365 A/AMP_deaminase_dom
IPR006330 Ado/ade_deaminase
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF00962 A_deaminase, 2 hits
SUPFAMiSSF51556 SSF51556, 1 hit
PROSITEiView protein in PROSITE
PS00485 A_DEAMINASE, 1 hit

Sequencei

Sequence statusi: Complete.

F5GWI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQTPAFDKP KVELHVHLDG SIKPETILYY GRRRGIALPA NTAEGLLNVI
60 70 80 90 100
GMDKPLTLPD FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV
110 120 130 140 150
RYSPHLLANS KVEPIPWNQA EGDLTPDEVV ALVGQGLQEG ERDFGVKARS
160 170 180 190 200
ILCCMRHQPN WSPKVVELCK KYQQQTVVAI DLAGDETIPG SSLLPGHVQA
210 220 230 240 250
YQAVDILKTE RLGHGYHTLE DQALYNRLRQ ENMHFEICPW SSYLTGAWKP
260 270 280 290 300
DTEHAVIRLK NDQANYSLNT DDPLIFKSTL DTDYQMTKRD MGFTEEEFKR
310 320 330
LNINAAKSSF LPEDEKRELL DLLYKAYGMP PSASAGQNL
Length:339
Mass (Da):38,293
Last modified:June 28, 2011 - v1
Checksum:i04B0ABF8FDAFF9BF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei339Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139352 Genomic DNA No translation available.
KF456921 Genomic DNA No translation available.
Z97053 Genomic DNA No translation available.
KU177893 mRNA Translation: ALQ33351.1
RefSeqiNP_001308980.1, NM_001322051.1
UniGeneiHs.654536

Genome annotation databases

EnsembliENST00000537820; ENSP00000441818; ENSG00000196839
GeneIDi100
UCSCiuc061xfm.1 human

Similar proteinsi

Entry informationi

Entry nameiF5GWI4_HUMAN
AccessioniPrimary (citable) accession number: F5GWI4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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