F4ZDX7 (F4ZDX7_9METZ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase subunit 1 RuleBase RU000369
EC=1.9.3.1 RuleBase RU000369

Gene names

Name:

COI EMBL AEB72094.1

Encoded on

Mitochondrion EMBL AEB72094.1

Organism

Erylus granularis EMBL AEB72094.1

Taxonomic identifier

1006795 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Porifera › Demospongiae › Tetractinomorpha › Astrophorida › Geodiidae › Erylus

Protein attributes

Sequence length	219 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B By similarity. RuleBase RU000369
Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. RuleBase RU000369
Pathway	Energy metabolism; oxidative phosphorylation. RuleBase RU000369
Subcellular location	Mitochondrion inner membrane; Multi-pass membrane protein By similarity RuleBase RU000369.
Sequence similarities	Belongs to the heme-copper respiratory oxidase family. RuleBase RU000369

Ontologies

Keywords
Biological process	Electron transport Respiratory chain RuleBase RU000369 Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane RuleBase RU000369
Domain	Transmembrane RuleBase RU000369
Ligand	Copper RuleBase RU000369 Heme RuleBase RU000369 Iron Metal-binding
Molecular function	Oxidoreductase RuleBase RU000369
Gene Ontology (GO)
Biological_process	aerobic respiration Inferred from electronic annotation. Source: InterPro electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW oxidative phosphorylation Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AEB72094.1
	Non-terminal residue	219	1	EMBL AEB72094.1

Sequences

	Sequence		Length	Mass (Da)
	F4ZDX7 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 8D1325B215AC781E	FASTA	219	23,667
	10 20 30 40 50 60 TLYLLFGAFS GMIGTGFSFL IRLELSAPGS MLGDDHLYNV IITAHGLIMI FFLVMPVMIG 70 80 90 100 110 120 GFGNWFVPLY IGAPDMAFPR LNNISFWVLP PSLILLLGSA FVEQGVGAGW TLYPPLSSVQ 130 140 150 160 170 180 AHSGGSVDAA IFSLHLAGIS SILGSMNFIT TIFNMRAPGI TMDRLPLFVW SILVTTYLLI 190 200 210 LSLPVLAGAI TMLLTDRNFN TTFFDPAGGG DPILFQHLF

References

[1]	"Molecular phylogeny of the Astrophorida (Porifera, Demospongiae(p)) reveals an unexpected high level of spicule homoplasy." Cardenas P., Xavier J.R., Reveillaud J., Schander C., Rapp H.T. PLoS ONE 6:E18318-E18318(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HM592729 Genomic DNA. Translation: AEB72094.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00705.
Family and domain databases
Gene3D	1.20.210.10. 1 hit.
InterPro	IPR000883. Cyt_c_Oxase_su1. IPR023616. Cyt_c_Oxase_su1_dom. [Graphical view]
PANTHER	PTHR10422. PTHR10422. 1 hit.
Pfam	PF00115. COX1. 1 hit. [Graphical view]
PRINTS	PR01165. CYCOXIDASEI.
SUPFAM	SSF81442. COX1. 1 hit.
PROSITE	PS50855. COX1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F4ZDX7_9METZ

Accession

Primary (citable) accession number: F4ZDX7

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	March 6, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)