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F4ZDX7

- F4ZDX7_9METZ

UniProt

F4ZDX7 - F4ZDX7_9METZ

Protein

Cytochrome c oxidase subunit 1

Gene

COI

Organism
Erylus granularis
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.UniRule annotation

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. aerobic respiration Source: InterPro
    2. oxidative phosphorylation Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Electron transport, Respiratory chainUniRule annotation, Transport

    Keywords - Ligandi

    CopperUniRule annotation, HemeUniRule annotation, Iron, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00705.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 1UniRule annotation (EC:1.9.3.1UniRule annotation)
    Gene namesi
    Name:COIImported
    Encoded oniMitochondrionImported
    OrganismiErylus granularisImported
    Taxonomic identifieri1006795 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeAstrophoridaGeodiidaeErylus

    Subcellular locationi

    Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell
    3. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the heme-copper respiratory oxidase family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Family and domain databases

    Gene3Di1.20.210.10. 1 hit.
    InterProiIPR000883. COX1.
    IPR023616. Cyt_c_Oxase_su1_dom.
    [Graphical view]
    PANTHERiPTHR10422. PTHR10422. 1 hit.
    PfamiPF00115. COX1. 1 hit.
    [Graphical view]
    PRINTSiPR01165. CYCOXIDASEI.
    SUPFAMiSSF81442. SSF81442. 1 hit.
    PROSITEiPS50855. COX1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    F4ZDX7-1 [UniParc]FASTAAdd to Basket

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    TLYLLFGAFS GMIGTGFSFL IRLELSAPGS MLGDDHLYNV IITAHGLIMI    50
    FFLVMPVMIG GFGNWFVPLY IGAPDMAFPR LNNISFWVLP PSLILLLGSA 100
    FVEQGVGAGW TLYPPLSSVQ AHSGGSVDAA IFSLHLAGIS SILGSMNFIT 150
    TIFNMRAPGI TMDRLPLFVW SILVTTYLLI LSLPVLAGAI TMLLTDRNFN 200
    TTFFDPAGGG DPILFQHLF 219
    Length:219
    Mass (Da):23,667
    Last modified:June 28, 2011 - v1
    Checksum:i8D1325B215AC781E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei219 – 2191Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HM592729 Genomic DNA. Translation: AEB72094.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HM592729 Genomic DNA. Translation: AEB72094.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00705 .

    Family and domain databases

    Gene3Di 1.20.210.10. 1 hit.
    InterProi IPR000883. COX1.
    IPR023616. Cyt_c_Oxase_su1_dom.
    [Graphical view ]
    PANTHERi PTHR10422. PTHR10422. 1 hit.
    Pfami PF00115. COX1. 1 hit.
    [Graphical view ]
    PRINTSi PR01165. CYCOXIDASEI.
    SUPFAMi SSF81442. SSF81442. 1 hit.
    PROSITEi PS50855. COX1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular phylogeny of the Astrophorida (Porifera, Demospongiae(p)) reveals an unexpected high level of spicule homoplasy."
      Cardenas P., Xavier J.R., Reveillaud J., Schander C., Rapp H.T.
      PLoS ONE 6:E18318-E18318(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiF4ZDX7_9METZ
    AccessioniPrimary (citable) accession number: F4ZDX7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)