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F4NBP1

- F4NBP1_HUMAN

UniProt

F4NBP1 - F4NBP1_HUMAN

Protein
Submitted name:

MHC class I antigen

Gene

HLA-B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 2 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. peptide antigen binding Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
    2. immune response Source: InterPro
    3. positive regulation of T cell mediated cytotoxicity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class I antigenImported
    Gene namesi
    Name:HLA-BImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. MHC class I protein complex Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiF4NBP1.

    Expressioni

    Gene expression databases

    BgeeiF4NBP1.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class I family.UniRule annotation
    Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view]
    PRINTSiPR01638. MHCCLASSI.
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    F4NBP1-1 [UniParc]FASTAAdd to Basket

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    SHSMRYFYTS VSRPGRGEPR FISVGYVDDT QFVRFDSDAA SPREEPRAPW    50
    IEQEGPEYWD RNTQIYKAQA QTDRESLRNL RGYYNQSEAG SHTLQSMYGC 100
    DVGPDGRLLR GHDQYAYDGK DYIALNEDLR SWTAADTAAQ ITQRKWEAAR 150
    EAEQRRAYLE GECVEWLRRY LENGKDKLER ADPPKTHVTH HPISDHEATL 200
    RCWALGFYPA EITLTWQQDG EDQTQDTELV ETRPAGDRTF QKWAAVVVPS 250
    GEEQRYTCHV QHEGLPKPLT LRW 273
    Length:273
    Mass (Da):31,704
    Last modified:October 3, 2012 - v2
    Checksum:i8DD43F53A9F7D784
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei273 – 2731Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR849754 Genomic DNA. Translation: CCA63173.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR849754 Genomic DNA. Translation: CCA63173.2 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F4NBP1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi HLA-B. human.
    NextBioi 35506681.

    Gene expression databases

    Bgeei F4NBP1.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view ]
    PRINTSi PR01638. MHCCLASSI.
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of 700 novel alleles at the HLA-A, -B, C,,DQB1,and - DRB1 loci from Chinese Marrow Donor Program volunteer donors."
      Qu J., Li J., Zheng Z., Chen H., Zhang H., Tian Z., Hua S., Yang H., Deng X., Cen Y., Cheng Z., Cheng G., Yi X., Wang W., Yang L., Wang J.
      Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiF4NBP1_HUMAN
    AccessioniPrimary (citable) accession number: F4NBP1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 13 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.