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F4LS67

- F4LS67_TEPAE

UniProt

F4LS67 - F4LS67_TEPAE

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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

TepRe1_0119

Organism
Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Note: Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTSP499229:GHS2-119-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:TepRe1_0119Imported
OrganismiTepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1)Imported
Taxonomic identifieri1209989 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeTepidanaerobacter
ProteomesiUP000008463: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

KOiK01921.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4LS67-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIAILIDEP RVSYLPGEEG LNEDLQKRKT VKNLKEVLSK RFECSLVKAD
60 70 80 90 100
SDIISKLQNE NVSLVFNLCN GIRGETRQAQ IPAILEFSGI PYTGSSILGH
110 120 130 140 150
TLAINKNYAC KVFKGSGVTT PEFISIYDKD DLMQLRNKEI KFPVLVKPCD
160 170 180 190 200
EGSGRGIHQD SLVYDFRSLK RKVQQELRLY NPPIMVTEYI KGREFTVGIL
210 220 230 240 250
GNGNNLKVLP ILEISFEALP DDLAKFYSFE VKANYADKTI FRCPAPLDNK
260 270 280 290 300
LKTKIENTAK KAYNALSLRD YARVDVRVKD DTPYVLEVNS LPGLQKGYSD
310 320 330
ITKMASACNL GYEGLILKIV ENAINRYKQA SEQKVV
Length:336
Mass (Da):37,827
Last modified:June 28, 2011 - v1
Checksum:iD2DEB5CC8EB2A455
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002728 Genomic DNA. Translation: AEE90330.1.
RefSeqiYP_004459637.1. NC_015519.1.

Genome annotation databases

EnsemblBacteriaiAEE90330; AEE90330; TepRe1_0119.
GeneIDi10596857.
KEGGitep:TepRe1_0119.
PATRICi54623086. VBITepSp18581_0126.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002728 Genomic DNA. Translation: AEE90330.1 .
RefSeqi YP_004459637.1. NC_015519.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEE90330 ; AEE90330 ; TepRe1_0119 .
GeneIDi 10596857.
KEGGi tep:TepRe1_0119.
PATRICi 54623086. VBITepSp18581_0126.

Phylogenomic databases

KOi K01921.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci TSP499229:GHS2-119-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Tepidanaerobacter sp. Re1."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Pagani I., Teshima H., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Lcollab F.I., Woyke T.
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 21804 / JCM 16047 / Re1Imported.

Entry informationi

Entry nameiF4LS67_TEPAE
AccessioniPrimary (citable) accession number: F4LS67
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 26, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3