ID   F4KZL4_HALH1            Unreviewed;       429 AA.
AC   F4KZL4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=(S)-3-amino-2-methylpropionate transaminase {ECO:0000313|EMBL:AEE49484.1};
DE            EC=2.6.1.22 {ECO:0000313|EMBL:AEE49484.1};
GN   OrderedLocusNames=Halhy_1593 {ECO:0000313|EMBL:AEE49484.1};
OS   Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O).
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Haliscomenobacteraceae;
OC   Haliscomenobacter.
OX   NCBI_TaxID=760192 {ECO:0000313|EMBL:AEE49484.1, ECO:0000313|Proteomes:UP000008461};
RN   [1] {ECO:0000313|EMBL:AEE49484.1, ECO:0000313|Proteomes:UP000008461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27775 / DSM 1100 / LMG 10767 / O
RC   {ECO:0000313|Proteomes:UP000008461};
RX   PubMed=21886862; DOI=10.4056/sigs.1964579;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Daligault H., Lapidus A., Zeytun A., Nolan M., Lucas S., Del Rio T.G.,
RA   Tice H., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA   Verbarg S., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of Haliscomenobacter hydrossis type strain (O).";
RL   Stand. Genomic Sci. 4:352-360(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 1100;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Pagani I.,
RA   Daligault H., Detter J.C., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Verbarg S., Frueling A.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "Complete sequence of chromosome of Haliscomenobacter hydrossis DSM 1100.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; CP002691; AEE49484.1; -; Genomic_DNA.
DR   RefSeq; WP_013764038.1; NC_015510.1.
DR   AlphaFoldDB; F4KZL4; -.
DR   STRING; 760192.Halhy_1593; -.
DR   GeneID; 78191511; -.
DR   KEGG; hhy:Halhy_1593; -.
DR   eggNOG; COG0160; Bacteria.
DR   HOGENOM; CLU_016922_10_0_10; -.
DR   OrthoDB; 730777at2; -.
DR   Proteomes; UP000008461; Chromosome.
DR   GO; GO:0047298; F:(S)-3-amino-2-methylpropionate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR049704; Aminotrans_3_PPA_site.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR   PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:AEE49484.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|RuleBase:RU003560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008461};
KW   Transferase {ECO:0000313|EMBL:AEE49484.1}.
SQ   SEQUENCE   429 AA;  46522 MW;  FB02C2B541C729C2 CRC64;
     MTSKELMERR NRVLPKAMYT TSTLNAASAK GAVFYDAEGV EYIDFSGGIG VLNAGHCPTP
     VSRAIAKQAQ TLMHTFFNVL THEPYVLLAE KLVEILPHGE ATKVMFVSTG AEAVENAVKI
     ARQATGRQGI ICYTGGFHGR TLMGMSLTSK VSYKTGCGPF APEIYRLPFP DYYHNGHGQA
     FDTFVEQELE NFKKYLSTVV APDNVAAVIL EPVQGEGGFY IVPPRYLQGL HEICKQHGIL
     LILDEVQSGF GRTGKWAAYE HYGVIPDIST WAKSMGSGIP IAAVMGKAEV MDKALPGTLG
     GTYAGNPVAC AGALASIEYM QQIDINRKGE QVGKTLLNFF NKLKKECPAI GEVRGLGAMV
     AIELVKNQNP NLPDPDLTKN LVTACAARGL FLISAGVYGN VIRVLCPLVI SQPMLKKGLE
     IMREELLKF
//