ID   F4KT93_HALH1            Unreviewed;       520 AA.
AC   F4KT93;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Glycosyl hydrolase BNR repeat-containing protein {ECO:0000313|EMBL:AEE51150.1};
GN   OrderedLocusNames=Halhy_3291 {ECO:0000313|EMBL:AEE51150.1};
OS   Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O).
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Haliscomenobacteraceae;
OC   Haliscomenobacter.
OX   NCBI_TaxID=760192 {ECO:0000313|EMBL:AEE51150.1, ECO:0000313|Proteomes:UP000008461};
RN   [1] {ECO:0000313|EMBL:AEE51150.1, ECO:0000313|Proteomes:UP000008461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27775 / DSM 1100 / LMG 10767 / O
RC   {ECO:0000313|Proteomes:UP000008461};
RX   PubMed=21886862; DOI=10.4056/sigs.1964579;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Daligault H., Lapidus A., Zeytun A., Nolan M., Lucas S., Del Rio T.G.,
RA   Tice H., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA   Verbarg S., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of Haliscomenobacter hydrossis type strain (O).";
RL   Stand. Genomic Sci. 4:352-360(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 1100;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Pagani I.,
RA   Daligault H., Detter J.C., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Verbarg S., Frueling A.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "Complete sequence of chromosome of Haliscomenobacter hydrossis DSM 1100.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002691; AEE51150.1; -; Genomic_DNA.
DR   RefSeq; WP_013765691.1; NC_015510.1.
DR   AlphaFoldDB; F4KT93; -.
DR   STRING; 760192.Halhy_3291; -.
DR   GeneID; 78193093; -.
DR   KEGG; hhy:Halhy_3291; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_0_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000008461; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   Gene3D; 2.60.40.1290; -; 2.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR029456; Sialidase_N.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR008377; Sialidase_trypan.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   Pfam; PF14873; BNR_assoc_N; 1.
DR   PRINTS; PR01803; TCSIALIDASE.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AEE51150.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008461}.
FT   DOMAIN          38..155
FT                   /note="Sialidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14873"
FT   DOMAIN          189..463
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
SQ   SEQUENCE   520 AA;  57393 MW;  5367004517F28E18 CRC64;
     MKNISIIFLF FTLSCCIQKQ NVVDAPQGFQ GDVWAFYTQN PILKGQEQNA LAKISIRMPQ
     GQGGQSLASL HLKIGAETDL RDIERMEVFV SGSNPEMEGA VLAASVKAEQ KILSIPCNAP
     LTAGENFLWL SCKLTAEANV QHKIDIQVEK VQLSKYGSVA AKIANTANPK YIGWALRQRN
     QEQVHTYRIP GLVTTKQGTL IAVYDVRYEN DRDLPANIDV AINRSKDGGQ TWEPMKIIMD
     MGPGANDGIG DPSILVDEQT GTIWVAALWS HGNRGWFGSG PGLSADETGQ FVLVKSEDDG
     QTWSKPINIT PQVKNPAWRL FFQGPGMGIT LRDGTLVFPA QYKDADAMPH STLIYSKDRG
     QTWQAGTGAK SNTTEAQLVE LSDGSLMLNM RDNRGGSRSV ATTKDLGQTW TEHPSSRSAL
     IEPICMASII RVASKKMGDP RDVLAFSNPH DAKERKNMSI KLSLDEGQTW PEAYHLLLDE
     RKGYGYSCLS MIDKNTIGLL YEGVRELYFV RIPLKDILKN
//