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Protein

L-aspartate oxidase

Gene

Poras_0264

Organism
Porphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / BCRC 10618 / JCM 6326 / LMG 13178 / VPI 4198) (Bacteroides asaccharolyticus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the oxidation of L-aspartate to iminoaspartate.UniRule annotation

Catalytic activityi

L-aspartate + O2 = iminosuccinate + H2O2.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes iminoaspartate from L-aspartate (oxidase route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. L-aspartate oxidase (Poras_0264)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes iminoaspartate from L-aspartate (oxidase route), the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
Biological processPyridine nucleotide biosynthesisUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

BioCyciPASA879243:G1GX8-272-MONOMER
UniPathwayiUPA00253; UER00326

Names & Taxonomyi

Protein namesi
Recommended name:
L-aspartate oxidaseUniRule annotation (EC:1.4.3.16UniRule annotation)
Gene namesi
Ordered Locus Names:Poras_0264Imported
OrganismiPorphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / BCRC 10618 / JCM 6326 / LMG 13178 / VPI 4198) (Bacteroides asaccharolyticus)Imported
Taxonomic identifieri879243 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
Proteomesi
  • UP000006545 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 29HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi879243.Poras_0264

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 383FAD_binding_2InterPro annotationAdd BLAST373
Domaini439 – 516Succ_DH_flav_CInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4108IYU Bacteria
COG0029 LUCA
KOiK00278
OMAiHCVQWLI
OrthoDBiPOG091H02TE

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR005288 NadB
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
PANTHERiPTHR42716:SF2 PTHR42716:SF2, 1 hit
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR00551 nadB, 1 hit

Sequencei

Sequence statusi: Complete.

F4KM99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLQQSPQRY DYIIIGGGLA GLYCAYFLAQ HGSVALIARR TIEESNSYYA
60 70 80 90 100
QGGMAAVTDQ EDSPTDHYED TIVAGRGLCI PEAVKILTDE APERINELIQ
110 120 130 140 150
MGMTFDSEDG HLALGLEGGH HHRRILHAGG DATGRLVTTF MIEQVRKAQH
160 170 180 190 200
ITIFDHHSAV QVLRSADGSH CQGLVTYDER AHHYDTILAS AVVLATGGAA
210 220 230 240 250
ALYYPTTNPP TALGDGLWLA SEVGAELMDL EFIQFHPTAL YLPGYASFLI
260 270 280 290 300
SEAVRGEGAY LVDKHGERFM PALHPLAELA PRDVVARSIF LKMQEEGTDH
310 320 330 340 350
VRLRLRHIDP KRLLQRFPTI SEHCRQLGLD ITDEIPVAPA AHYTVGGIGV
360 370 380 390 400
DLNGCTRLPG LYAVGEVSST GVMGANRLAS NSLIECIVFG KRIADYAIAH
410 420 430 440 450
PITPTDTASL AVPTNLPDLS WSLDKEQIYA LEEQTKISRQ MGDILMSRVG
460 470 480 490 500
IIRSKEGLIE ALHALQHLSD TLAEDAQHSI HAYMTRRRVE VAHMMAHAAL
510 520 530
LREESRGGHY RSDYTETLPE SEAYRTRLLD GEITHQPIN
Length:539
Mass (Da):59,286
Last modified:June 28, 2011 - v1
Checksum:i8AA988284FA5638B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002689 Genomic DNA Translation: AEE12218.1
RefSeqiWP_004330468.1, NC_015501.1

Genome annotation databases

EnsemblBacteriaiAEE12218; AEE12218; Poras_0264
KEGGipah:Poras_0264

Similar proteinsi

Entry informationi

Entry nameiF4KM99_PORAD
AccessioniPrimary (citable) accession number: F4KM99
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health