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F4K1B1 (RPAP2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog

EC=3.1.3.16
Alternative name(s):
RNA polymerase II-associated protein 2 homolog
Gene names
Ordered Locus Names:At5g26760
ORF Names:F2P16.20
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length735 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the RPAP2 family.

Contains 1 RTR1-type zinc finger.

Sequence caution

The sequence AAB61054.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: F4K1B1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Note: Derived from EST data. No experimental confirmation available.
Isoform 2 (identifier: F4K1B1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-305: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 735735Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog
PRO_0000416291

Regions

Zinc finger33 – 11886RTR1-type

Natural variations

Alternative sequence1 – 305305Missing in isoform 2.
VSP_042606

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: E782F1B107D5D5B7

FASTA73581,058
        10         20         30         40         50         60 
MAKDNEAIAI NDAVHKLQLY MLENTTDQNQ LFAARKLMSR SDYEDVVTER AIAKLCGYTL 

        70         80         90        100        110        120 
CQRFLPSDVS RRGKYRISLK DHKVYDLQET SKFCSAGCLI DSKTFSGSLQ EARTLEFDSV 

       130        140        150        160        170        180 
KLNEILDLFG DSLEVKGSLD VNKDLDLSKL MIKENFGVRG EELSLEKWMG PSNAVEGYVP 

       190        200        210        220        230        240 
FDRSKSSNDS KATTQSNQEK HEMDFTSTVI MPDVNSVSKL PPQTKQASTV VESVDGKGKT 

       250        260        270        280        290        300 
VLKEQTVVPP TKKVSRFRRE KEKEKKTFGV DGMGCAQEKT TVLPRKILSF CNEIEKDFKN 

       310        320        330        340        350        360 
FGFDEMGLAS SAMMSDGYGV EYSVSKQPQC SMEDSLSCKL KGDLQTLDGK NTLSGSSSGS 

       370        380        390        400        410        420 
NTKGSKTKPE KSRKKIISVE YHANSYEDGE EILAAESYER HKAQDVCSSS EIVTKSCLKI 

       430        440        450        460        470        480 
SGSKKLSRSV TWADQNDGRG DLCEVRNNDN AAGPSLSSND IEDVNSLSRL ALAEALATAL 

       490        500        510        520        530        540 
SQAAEAVSSG NSDASDATAK AGIILLPSTH QLDEEVTEEH SEEEMTEEEP TLLKWPNKPG 

       550        560        570        580        590        600 
IPDSDLFDRD QSWFDGPPEG FNLTLSNFAV MWDSLFGWVS SSSLAYIYGK EESAHEEFLL 

       610        620        630        640        650        660 
VNGKEYPRRI IMVDGLSSEI KQTIAGCLAR ALPRVVTHLR LPIAISELEK GLGSLLETMS 

       670        680        690        700        710        720 
LTGAVPSFRV KEWLVIVLLF LDALSVSRIP RIAPYISNRD KILEGSGIGN EEYETMKDIL 

       730 
LPLGRVPQFA TRSGA 

« Hide

Isoform 2 [UniParc].

Checksum: F409A9A8952D29BD
Show »

FASTA43046,685

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF007270 Genomic DNA. Translation: AAB61054.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED93597.1.
CP002688 Genomic DNA. Translation: AED93598.1.
BT015786 mRNA. Translation: AAU90076.1.
PIRT01757.
RefSeqNP_198028.2. NM_122558.3. [F4K1B1-2]
NP_974839.1. NM_203110.1. [F4K1B1-1]
UniGeneAt.44801.

3D structure databases

ProteinModelPortalF4K1B1.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEF4K1B1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G26760.2; AT5G26760.2; AT5G26760. [F4K1B1-1]
GeneID832734.
KEGGath:AT5G26760.

Organism-specific databases

TAIRAT5G26760.

Phylogenomic databases

HOGENOMHOG000241200.
OMAHANSYED.
PhylomeDBF4K1B1.

Family and domain databases

InterProIPR007308. DUF408.
[Graphical view]
PfamPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEPS51479. ZF_RTR1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROF4K1B1.

Entry information

Entry nameRPAP2_ARATH
AccessionPrimary (citable) accession number: F4K1B1
Secondary accession number(s): O04626, Q5XF30
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: June 28, 2011
Last modified: May 14, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names