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Protein

Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog

Gene

At5g26760

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi56ZincPROSITE-ProRule annotation1
Metal bindingi61ZincPROSITE-ProRule annotation1
Metal bindingi94ZincPROSITE-ProRule annotation1
Metal bindingi98ZincPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri33 – 118RTR1-typePROSITE-ProRule annotationAdd BLAST86

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2 homolog
Gene namesi
Ordered Locus Names:At5g26760
ORF Names:F2P16.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G26760.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004162911 – 735Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homologAdd BLAST735

Proteomic databases

PaxDbiF4K1B1.
PRIDEiF4K1B1.

PTM databases

iPTMnetiF4K1B1.

Expressioni

Gene expression databases

GenevisibleiF4K1B1. AT.

Interactioni

Protein-protein interaction databases

BioGridi18009. 1 interactor.
STRINGi3702.AT5G26760.2.

Structurei

3D structure databases

ProteinModelPortaliF4K1B1.
SMRiF4K1B1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.Curated
Contains 1 RTR1-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri33 – 118RTR1-typePROSITE-ProRule annotationAdd BLAST86

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG4780. Eukaryota.
ENOG410ZZZC. LUCA.
HOGENOMiHOG000241200.
InParanoidiF4K1B1.
KOiK20827.
OMAiHANSYED.
OrthoDBiEOG093604TT.
PhylomeDBiF4K1B1.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: F4K1B1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAKDNEAIAI NDAVHKLQLY MLENTTDQNQ LFAARKLMSR SDYEDVVTER
60 70 80 90 100
AIAKLCGYTL CQRFLPSDVS RRGKYRISLK DHKVYDLQET SKFCSAGCLI
110 120 130 140 150
DSKTFSGSLQ EARTLEFDSV KLNEILDLFG DSLEVKGSLD VNKDLDLSKL
160 170 180 190 200
MIKENFGVRG EELSLEKWMG PSNAVEGYVP FDRSKSSNDS KATTQSNQEK
210 220 230 240 250
HEMDFTSTVI MPDVNSVSKL PPQTKQASTV VESVDGKGKT VLKEQTVVPP
260 270 280 290 300
TKKVSRFRRE KEKEKKTFGV DGMGCAQEKT TVLPRKILSF CNEIEKDFKN
310 320 330 340 350
FGFDEMGLAS SAMMSDGYGV EYSVSKQPQC SMEDSLSCKL KGDLQTLDGK
360 370 380 390 400
NTLSGSSSGS NTKGSKTKPE KSRKKIISVE YHANSYEDGE EILAAESYER
410 420 430 440 450
HKAQDVCSSS EIVTKSCLKI SGSKKLSRSV TWADQNDGRG DLCEVRNNDN
460 470 480 490 500
AAGPSLSSND IEDVNSLSRL ALAEALATAL SQAAEAVSSG NSDASDATAK
510 520 530 540 550
AGIILLPSTH QLDEEVTEEH SEEEMTEEEP TLLKWPNKPG IPDSDLFDRD
560 570 580 590 600
QSWFDGPPEG FNLTLSNFAV MWDSLFGWVS SSSLAYIYGK EESAHEEFLL
610 620 630 640 650
VNGKEYPRRI IMVDGLSSEI KQTIAGCLAR ALPRVVTHLR LPIAISELEK
660 670 680 690 700
GLGSLLETMS LTGAVPSFRV KEWLVIVLLF LDALSVSRIP RIAPYISNRD
710 720 730
KILEGSGIGN EEYETMKDIL LPLGRVPQFA TRSGA
Note: Derived from EST data. No experimental confirmation available.
Length:735
Mass (Da):81,058
Last modified:June 28, 2011 - v1
Checksum:iE782F1B107D5D5B7
GO
Isoform 2 (identifier: F4K1B1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-305: Missing.

Note: No experimental confirmation available.
Show »
Length:430
Mass (Da):46,685
Checksum:iF409A9A8952D29BD
GO

Sequence cautioni

The sequence AAB61054 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0426061 – 305Missing in isoform 2. 1 PublicationAdd BLAST305

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF007270 Genomic DNA. Translation: AAB61054.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED93597.1.
CP002688 Genomic DNA. Translation: AED93598.1.
BT015786 mRNA. Translation: AAU90076.1.
PIRiT01757.
RefSeqiNP_198028.2. NM_122558.4. [F4K1B1-2]
NP_974839.1. NM_203110.2. [F4K1B1-1]
UniGeneiAt.44801.

Genome annotation databases

EnsemblPlantsiAT5G26760.2; AT5G26760.2; AT5G26760. [F4K1B1-1]
GeneIDi832734.
GrameneiAT5G26760.2; AT5G26760.2; AT5G26760.
KEGGiath:AT5G26760.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF007270 Genomic DNA. Translation: AAB61054.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED93597.1.
CP002688 Genomic DNA. Translation: AED93598.1.
BT015786 mRNA. Translation: AAU90076.1.
PIRiT01757.
RefSeqiNP_198028.2. NM_122558.4. [F4K1B1-2]
NP_974839.1. NM_203110.2. [F4K1B1-1]
UniGeneiAt.44801.

3D structure databases

ProteinModelPortaliF4K1B1.
SMRiF4K1B1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi18009. 1 interactor.
STRINGi3702.AT5G26760.2.

PTM databases

iPTMnetiF4K1B1.

Proteomic databases

PaxDbiF4K1B1.
PRIDEiF4K1B1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G26760.2; AT5G26760.2; AT5G26760. [F4K1B1-1]
GeneIDi832734.
GrameneiAT5G26760.2; AT5G26760.2; AT5G26760.
KEGGiath:AT5G26760.

Organism-specific databases

TAIRiAT5G26760.

Phylogenomic databases

eggNOGiKOG4780. Eukaryota.
ENOG410ZZZC. LUCA.
HOGENOMiHOG000241200.
InParanoidiF4K1B1.
KOiK20827.
OMAiHANSYED.
OrthoDBiEOG093604TT.
PhylomeDBiF4K1B1.

Miscellaneous databases

PROiF4K1B1.

Gene expression databases

GenevisibleiF4K1B1. AT.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPAP2_ARATH
AccessioniPrimary (citable) accession number: F4K1B1
Secondary accession number(s): O04626, Q5XF30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.