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F4K1B1

- RPAP2_ARATH

UniProt

F4K1B1 - RPAP2_ARATH

Protein

Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog

Gene

At5g26760

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri33 – 11886RTR1-typeAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog (EC:3.1.3.16)
    Alternative name(s):
    RNA polymerase II-associated protein 2 homolog
    Gene namesi
    Ordered Locus Names:At5g26760
    ORF Names:F2P16.20
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G26760.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 735735Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homologPRO_0000416291Add
    BLAST

    Proteomic databases

    PRIDEiF4K1B1.

    Structurei

    3D structure databases

    ProteinModelPortaliF4K1B1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RPAP2 family.Curated
    Contains 1 RTR1-type zinc finger.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri33 – 11886RTR1-typeAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    HOGENOMiHOG000241200.
    OMAiHANSYED.
    PhylomeDBiF4K1B1.

    Family and domain databases

    InterProiIPR007308. DUF408.
    [Graphical view]
    PfamiPF04181. RPAP2_Rtr1. 1 hit.
    [Graphical view]
    PROSITEiPS51479. ZF_RTR1. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: F4K1B1-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAKDNEAIAI NDAVHKLQLY MLENTTDQNQ LFAARKLMSR SDYEDVVTER    50
    AIAKLCGYTL CQRFLPSDVS RRGKYRISLK DHKVYDLQET SKFCSAGCLI 100
    DSKTFSGSLQ EARTLEFDSV KLNEILDLFG DSLEVKGSLD VNKDLDLSKL 150
    MIKENFGVRG EELSLEKWMG PSNAVEGYVP FDRSKSSNDS KATTQSNQEK 200
    HEMDFTSTVI MPDVNSVSKL PPQTKQASTV VESVDGKGKT VLKEQTVVPP 250
    TKKVSRFRRE KEKEKKTFGV DGMGCAQEKT TVLPRKILSF CNEIEKDFKN 300
    FGFDEMGLAS SAMMSDGYGV EYSVSKQPQC SMEDSLSCKL KGDLQTLDGK 350
    NTLSGSSSGS NTKGSKTKPE KSRKKIISVE YHANSYEDGE EILAAESYER 400
    HKAQDVCSSS EIVTKSCLKI SGSKKLSRSV TWADQNDGRG DLCEVRNNDN 450
    AAGPSLSSND IEDVNSLSRL ALAEALATAL SQAAEAVSSG NSDASDATAK 500
    AGIILLPSTH QLDEEVTEEH SEEEMTEEEP TLLKWPNKPG IPDSDLFDRD 550
    QSWFDGPPEG FNLTLSNFAV MWDSLFGWVS SSSLAYIYGK EESAHEEFLL 600
    VNGKEYPRRI IMVDGLSSEI KQTIAGCLAR ALPRVVTHLR LPIAISELEK 650
    GLGSLLETMS LTGAVPSFRV KEWLVIVLLF LDALSVSRIP RIAPYISNRD 700
    KILEGSGIGN EEYETMKDIL LPLGRVPQFA TRSGA 735

    Note: Derived from EST data. No experimental confirmation available.

    Length:735
    Mass (Da):81,058
    Last modified:June 28, 2011 - v1
    Checksum:iE782F1B107D5D5B7
    GO
    Isoform 2 (identifier: F4K1B1-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-305: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:430
    Mass (Da):46,685
    Checksum:iF409A9A8952D29BD
    GO

    Sequence cautioni

    The sequence AAB61054.1 differs from that shown. Reason: Erroneous gene model prediction.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 305305Missing in isoform 2. 1 PublicationVSP_042606Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF007270 Genomic DNA. Translation: AAB61054.1. Sequence problems.
    CP002688 Genomic DNA. Translation: AED93597.1.
    CP002688 Genomic DNA. Translation: AED93598.1.
    BT015786 mRNA. Translation: AAU90076.1.
    PIRiT01757.
    RefSeqiNP_198028.2. NM_122558.3. [F4K1B1-2]
    NP_974839.1. NM_203110.1. [F4K1B1-1]
    UniGeneiAt.44801.

    Genome annotation databases

    EnsemblPlantsiAT5G26760.2; AT5G26760.2; AT5G26760. [F4K1B1-1]
    GeneIDi832734.
    KEGGiath:AT5G26760.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF007270 Genomic DNA. Translation: AAB61054.1 . Sequence problems.
    CP002688 Genomic DNA. Translation: AED93597.1 .
    CP002688 Genomic DNA. Translation: AED93598.1 .
    BT015786 mRNA. Translation: AAU90076.1 .
    PIRi T01757.
    RefSeqi NP_198028.2. NM_122558.3. [F4K1B1-2 ]
    NP_974839.1. NM_203110.1. [F4K1B1-1 ]
    UniGenei At.44801.

    3D structure databases

    ProteinModelPortali F4K1B1.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F4K1B1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G26760.2 ; AT5G26760.2 ; AT5G26760 . [F4K1B1-1 ]
    GeneIDi 832734.
    KEGGi ath:AT5G26760.

    Organism-specific databases

    TAIRi AT5G26760.

    Phylogenomic databases

    HOGENOMi HOG000241200.
    OMAi HANSYED.
    PhylomeDBi F4K1B1.

    Miscellaneous databases

    PROi F4K1B1.

    Family and domain databases

    InterProi IPR007308. DUF408.
    [Graphical view ]
    Pfami PF04181. RPAP2_Rtr1. 1 hit.
    [Graphical view ]
    PROSITEi PS51479. ZF_RTR1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
      Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
      , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
      Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Arabidopsis ORF clones."
      Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.
      Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiRPAP2_ARATH
    AccessioniPrimary (citable) accession number: F4K1B1
    Secondary accession number(s): O04626, Q5XF30
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 21, 2012
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3