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F4K1B1

- RPAP2_ARATH

UniProt

F4K1B1 - RPAP2_ARATH

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Protein

Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog

Gene

At5g26760

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri33 – 11886RTR1-typeAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2 homolog
Gene namesi
Ordered Locus Names:At5g26760
ORF Names:F2P16.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G26760.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 735735Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homologPRO_0000416291Add
BLAST

Proteomic databases

PRIDEiF4K1B1.

Structurei

3D structure databases

ProteinModelPortaliF4K1B1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.Curated
Contains 1 RTR1-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri33 – 11886RTR1-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000241200.
InParanoidiF4K1B1.
OMAiHANSYED.
PhylomeDBiF4K1B1.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: F4K1B1-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAKDNEAIAI NDAVHKLQLY MLENTTDQNQ LFAARKLMSR SDYEDVVTER
60 70 80 90 100
AIAKLCGYTL CQRFLPSDVS RRGKYRISLK DHKVYDLQET SKFCSAGCLI
110 120 130 140 150
DSKTFSGSLQ EARTLEFDSV KLNEILDLFG DSLEVKGSLD VNKDLDLSKL
160 170 180 190 200
MIKENFGVRG EELSLEKWMG PSNAVEGYVP FDRSKSSNDS KATTQSNQEK
210 220 230 240 250
HEMDFTSTVI MPDVNSVSKL PPQTKQASTV VESVDGKGKT VLKEQTVVPP
260 270 280 290 300
TKKVSRFRRE KEKEKKTFGV DGMGCAQEKT TVLPRKILSF CNEIEKDFKN
310 320 330 340 350
FGFDEMGLAS SAMMSDGYGV EYSVSKQPQC SMEDSLSCKL KGDLQTLDGK
360 370 380 390 400
NTLSGSSSGS NTKGSKTKPE KSRKKIISVE YHANSYEDGE EILAAESYER
410 420 430 440 450
HKAQDVCSSS EIVTKSCLKI SGSKKLSRSV TWADQNDGRG DLCEVRNNDN
460 470 480 490 500
AAGPSLSSND IEDVNSLSRL ALAEALATAL SQAAEAVSSG NSDASDATAK
510 520 530 540 550
AGIILLPSTH QLDEEVTEEH SEEEMTEEEP TLLKWPNKPG IPDSDLFDRD
560 570 580 590 600
QSWFDGPPEG FNLTLSNFAV MWDSLFGWVS SSSLAYIYGK EESAHEEFLL
610 620 630 640 650
VNGKEYPRRI IMVDGLSSEI KQTIAGCLAR ALPRVVTHLR LPIAISELEK
660 670 680 690 700
GLGSLLETMS LTGAVPSFRV KEWLVIVLLF LDALSVSRIP RIAPYISNRD
710 720 730
KILEGSGIGN EEYETMKDIL LPLGRVPQFA TRSGA

Note: Derived from EST data. No experimental confirmation available.

Length:735
Mass (Da):81,058
Last modified:June 28, 2011 - v1
Checksum:iE782F1B107D5D5B7
GO
Isoform 2 (identifier: F4K1B1-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-305: Missing.

Note: No experimental confirmation available.

Show »
Length:430
Mass (Da):46,685
Checksum:iF409A9A8952D29BD
GO

Sequence cautioni

The sequence AAB61054.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 305305Missing in isoform 2. 1 PublicationVSP_042606Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF007270 Genomic DNA. Translation: AAB61054.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED93597.1.
CP002688 Genomic DNA. Translation: AED93598.1.
BT015786 mRNA. Translation: AAU90076.1.
PIRiT01757.
RefSeqiNP_198028.2. NM_122558.3. [F4K1B1-2]
NP_974839.1. NM_203110.1. [F4K1B1-1]
UniGeneiAt.44801.

Genome annotation databases

EnsemblPlantsiAT5G26760.2; AT5G26760.2; AT5G26760. [F4K1B1-1]
GeneIDi832734.
KEGGiath:AT5G26760.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF007270 Genomic DNA. Translation: AAB61054.1 . Sequence problems.
CP002688 Genomic DNA. Translation: AED93597.1 .
CP002688 Genomic DNA. Translation: AED93598.1 .
BT015786 mRNA. Translation: AAU90076.1 .
PIRi T01757.
RefSeqi NP_198028.2. NM_122558.3. [F4K1B1-2 ]
NP_974839.1. NM_203110.1. [F4K1B1-1 ]
UniGenei At.44801.

3D structure databases

ProteinModelPortali F4K1B1.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F4K1B1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G26760.2 ; AT5G26760.2 ; AT5G26760 . [F4K1B1-1 ]
GeneIDi 832734.
KEGGi ath:AT5G26760.

Organism-specific databases

TAIRi AT5G26760.

Phylogenomic databases

HOGENOMi HOG000241200.
InParanoidi F4K1B1.
OMAi HANSYED.
PhylomeDBi F4K1B1.

Miscellaneous databases

PROi F4K1B1.

Family and domain databases

InterProi IPR007308. DUF408.
[Graphical view ]
Pfami PF04181. RPAP2_Rtr1. 1 hit.
[Graphical view ]
PROSITEi PS51479. ZF_RTR1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Arabidopsis ORF clones."
    Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: cv. Columbia.

Entry informationi

Entry nameiRPAP2_ARATH
AccessioniPrimary (citable) accession number: F4K1B1
Secondary accession number(s): O04626, Q5XF30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: June 28, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3