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Protein

Mitochondrial carrier protein CoAc2

Gene

COAC2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the accumulation of coenzyme A in the mitochondrial matrix.1 Publication

GO - Molecular functioni

  • coenzyme A transmembrane transporter activity Source: TAIR

GO - Biological processi

  • mitochondrial coenzyme A transmembrane transport Source: UniProtKB

Keywordsi

Biological processTransport

Protein family/group databases

TCDBi2.A.29.12.6. the mitochondrial carrier (mc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial carrier protein CoAc2Curated
Alternative name(s):
AtCoAc21 Publication
Mitochondrial coenzyme A transporter CoAc2Curated
Gene namesi
Name:COAC21 Publication
Ordered Locus Names:At4g26180Imported
ORF Names:F20B18.290Imported, T25K17.6Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G26180.
TAIRilocus:2120878. AT4G26180.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei73 – 93Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei117 – 137Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei185 – 205Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei223 – 243Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei281 – 301Helical; Name=6Sequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-UniRule
  • mitochondrial inner membrane Source: UniProtKB
  • mitochondrion Source: TAIR

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004409861 – 331Mitochondrial carrier protein CoAc2Add BLAST331

Expressioni

Tissue specificityi

Expressed throughout the plant.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G26180.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati15 – 101Solcar 1PROSITE-ProRule annotationAdd BLAST87
Repeati111 – 210Solcar 2PROSITE-ProRule annotationAdd BLAST100
Repeati217 – 308Solcar 3PROSITE-ProRule annotationAdd BLAST92

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
HOGENOMiHOG000165726.
OMAiRRAEFHG.
OrthoDBiEOG09360FLH.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: F4JU70-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAEGEEKNGI IDSIPLFAKE LIAGGVTGGI AKTAVAPLER IKILFQTRRD
60 70 80 90 100
EFKRIGLVGS INKIGKTEGL MGFYRGNGAS VARIVPYAAL HYMAYEEYRR
110 120 130 140 150
WIIFGFPDTT RGPLLDLVAG SFAGGTAVLF TYPLDLVRTK LAYQVVGSAK
160 170 180 190 200
TQVKAIPVEQ IIYRGIVDCF SRTYRESGAR GLYRGVAPSL YGIFPYAGLK
210 220 230 240 250
FYFYEEMKRH VPPEHKQDIS LKLVCGSVAG LLGQTLTYPL DVVRRQMQVE
260 270 280 290 300
RLYSAVKEET RRGTMQTLFK IAREEGWKQL FSGLSINYLK VVPSVAIGFT
310 320 330
VYDIMKLHLR VPPREEPEAE AVTTRKRKVF T
Length:331
Mass (Da):37,093
Last modified:April 12, 2017 - v1
Checksum:i13B59FA2F88734CF
GO

Sequence cautioni

The sequence CAB39683 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79473 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049171 Genomic DNA. No translation available.
AL049483 Genomic DNA. Translation: CAB39683.1. Sequence problems.
AL161564 Genomic DNA. Translation: CAB79473.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85167.2.
PIRiT04273.
RefSeqiNP_001320068.1. NM_001341785.1.
UniGeneiAt.32203.

Genome annotation databases

EnsemblPlantsiAT4G26180.1; AT4G26180.1; AT4G26180. [F4JU70-1]
GeneIDi828724.
GrameneiAT4G26180.1; AT4G26180.1; AT4G26180.
KEGGiath:AT4G26180.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiCOAC2_ARATH
AccessioniPrimary (citable) accession number: F4JU70
Secondary accession number(s): Q9SZI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2017
Last sequence update: April 12, 2017
Last modified: August 30, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families