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Protein

Diacylglycerol kinase 6

Gene

DGK6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress.1 Publication

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processPlant defense, Stress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase 6 (EC:2.7.1.107)
Short name:
AtDGK6
Short name:
DAG kinase 6
Alternative name(s):
Diglyceride kinase 6
Short name:
DGK 6
Gene namesi
Name:DGK6
Ordered Locus Names:At4g28130
ORF Names:F26K10.10, T13J8.230
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRilocus:2123703. AT4G28130.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: TAIR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004221141 – 466Diacylglycerol kinase 6Add BLAST466

Proteomic databases

PaxDbiF4JKI3.

Expressioni

Gene expression databases

GenevisibleiF4JKI3. AT.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi3702.AT4G28130.1.

Structurei

3D structure databases

ProteinModelPortaliF4JKI3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 194DAGKcPROSITE-ProRule annotationAdd BLAST152

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1169. Eukaryota.
ENOG410XQVB. LUCA.
HOGENOMiHOG000241061.
InParanoidiF4JKI3.
KOiK00901.
OMAiVANCEEF.
OrthoDBiEOG093608DB.

Family and domain databases

Gene3Di3.40.50.10330. 1 hit.
InterProiView protein in InterPro
IPR017438. ATP-NAD_kinase_dom_1.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016064. NAD/diacylglycerol_kinase.
PfamiView protein in Pfam
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
SMARTiView protein in SMART
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SUPFAMiSSF111331. SSF111331. 2 hits.
PROSITEiView protein in PROSITE
PS50146. DAGK. 1 hit.

Sequencei

Sequence statusi: Complete.

F4JKI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQSETSMEK YKNLSDFLKK FFIPSYVLSP EDEPEAQISC TTAPENPILV
60 70 80 90 100
FINSKSGGQL GAELILTYRT LLNDKQVFDL EVETPDKVLQ RIYLNLERLK
110 120 130 140 150
DDSLASKIRD KLKIIVAGGD GTAGWLLGVV SDLNLSNPPP IATVPLGTGN
160 170 180 190 200
NLPFAFGWGK KNPGTDRSSV ESFLGKVINA KEMKIDNWKI LMRMKHPKEG
210 220 230 240 250
SCDITLKLPH SLPRIFPSDQ ENMEGYHTYR GGFWNYFSLG MDAQVSYAFH
260 270 280 290 300
SQRKLHPERF KNQLVNQSTY LKLSCTQGWF FASLFHPSSQ NIAKLAKIQI
310 320 330 340 350
CDRNGQWNDL HIPQSIRSIV CLNLPSFSGG LNPWGTPNPK KQRDRSLTAP
360 370 380 390 400
FVDDGLIEIV GFRNAWHGLI LLSPNGHGTR LAQANRVRLE FKKGAAKHAY
410 420 430 440 450
MRIDGEPWKQ PLPSNDETVM VEISHHGQVN MLATQNCRSK SMYESSSIIR
460
FSNDEDDSSV VENEEF
Length:466
Mass (Da):52,490
Last modified:June 28, 2011 - v1
Checksum:iC94BA5687CFFF252
GO

Sequence cautioni

The sequence CAB36781 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79614 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79615 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035524 Genomic DNA. Translation: CAB36781.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79614.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79615.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85443.1.
PIRiC85327.
D85327.
T02913.
T09029.
RefSeqiNP_194542.2. NM_118953.2.
UniGeneiAt.54533.

Genome annotation databases

EnsemblPlantsiAT4G28130.1; AT4G28130.1; AT4G28130.
GeneIDi828928.
GrameneiAT4G28130.1; AT4G28130.1; AT4G28130.
KEGGiath:AT4G28130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035524 Genomic DNA. Translation: CAB36781.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79614.1. Sequence problems.
AL161572 Genomic DNA. Translation: CAB79615.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85443.1.
PIRiC85327.
D85327.
T02913.
T09029.
RefSeqiNP_194542.2. NM_118953.2.
UniGeneiAt.54533.

3D structure databases

ProteinModelPortaliF4JKI3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G28130.1.

Proteomic databases

PaxDbiF4JKI3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G28130.1; AT4G28130.1; AT4G28130.
GeneIDi828928.
GrameneiAT4G28130.1; AT4G28130.1; AT4G28130.
KEGGiath:AT4G28130.

Organism-specific databases

AraportiAT4G28130.
TAIRilocus:2123703. AT4G28130.

Phylogenomic databases

eggNOGiKOG1169. Eukaryota.
ENOG410XQVB. LUCA.
HOGENOMiHOG000241061.
InParanoidiF4JKI3.
KOiK00901.
OMAiVANCEEF.
OrthoDBiEOG093608DB.

Miscellaneous databases

PROiPR:F4JKI3.

Gene expression databases

GenevisibleiF4JKI3. AT.

Family and domain databases

Gene3Di3.40.50.10330. 1 hit.
InterProiView protein in InterPro
IPR017438. ATP-NAD_kinase_dom_1.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016064. NAD/diacylglycerol_kinase.
PfamiView protein in Pfam
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
SMARTiView protein in SMART
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SUPFAMiSSF111331. SSF111331. 2 hits.
PROSITEiView protein in PROSITE
PS50146. DAGK. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDGK6_ARATH
AccessioniPrimary (citable) accession number: F4JKI3
Secondary accession number(s): Q9M0J4, Q9SUC8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: June 28, 2011
Last modified: May 10, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.