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Protein

Amine oxidase

Gene

At1g31690

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • L-topaquinoneUniRule annotation, Cu cationUniRule annotationNote: Contains 1 topaquinone per subunit.UniRule annotation
  • L-topaquinoneUniRule annotationNote: Contains 1 topaquinone per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei322Proton acceptorUniRule annotation1
Active sitei410Schiff-base intermediate with substrate; via topaquinoneUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-ATH-211945 Phase I - Functionalization of compounds
R-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Amine oxidaseUniRule annotation (EC:1.4.3.-UniRule annotation)
Gene namesi
Ordered Locus Names:At1g31690Imported
ORF Names:F27M3.11Imported, F27M3_11Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G31690
TAIRilocus:2028636 AT1G31690

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500330959721 – 677Amine oxidaseSequence analysisAdd BLAST657

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4102',4',5'-topaquinoneUniRule annotation1

Post-translational modificationi

Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.UniRule annotation

Keywords - PTMi

TPQUniRule annotation

Proteomic databases

PaxDbiF4IAX0
PRIDEiF4IAX0

Expressioni

Gene expression databases

ExpressionAtlasiF4IAX0 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G31690.1

Structurei

3D structure databases

ProteinModelPortaliF4IAX0
SMRiF4IAX0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 115Cu_amine_oxidN2InterPro annotationAdd BLAST89
Domaini123 – 215Cu_amine_oxidN3InterPro annotationAdd BLAST93
Domaini245 – 662Cu_amine_oxidInterPro annotationAdd BLAST418

Sequence similaritiesi

Belongs to the copper/topaquinone oxidase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1186 Eukaryota
COG3733 LUCA
InParanoidiF4IAX0
KOiK00276
OMAiGKGFHID
OrthoDBiEOG093605A3

Family and domain databases

Gene3Di2.70.98.20, 1 hit
InterProiView protein in InterPro
IPR000269 Cu_amine_oxidase
IPR015798 Cu_amine_oxidase_C
IPR036460 Cu_amine_oxidase_C_sf
IPR016182 Cu_amine_oxidase_N-reg
IPR015800 Cu_amine_oxidase_N2
IPR015802 Cu_amine_oxidase_N3
PANTHERiPTHR10638 PTHR10638, 1 hit
PfamiView protein in Pfam
PF01179 Cu_amine_oxid, 1 hit
PF02727 Cu_amine_oxidN2, 1 hit
PF02728 Cu_amine_oxidN3, 1 hit
SUPFAMiSSF49998 SSF49998, 1 hit
SSF54416 SSF54416, 2 hits
PROSITEiView protein in PROSITE
PS01165 COPPER_AMINE_OXID_2, 1 hit

Sequencei

Sequence statusi: Complete.

F4IAX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQVHLTIFI FSSIFVISSS SFIPPPHPFD PLTETELKLV RNIINKSYPI
60 70 80 90 100
GHNHKFTFQY VGLNEPEKSL VLSWHSSPDR NVKPPPRQAF VIARDKGMSR
110 120 130 140 150
EIVIDFSTRA IVSNKIHVGN GNPMLTIDEQ QAATAVVQKY KPFCDSIIKR
160 170 180 190 200
GLNLSEVVVT SSTMGWFGET KTKRFIRTIP FYLNGSVNTY LRPIEGMTII
210 220 230 240 250
VNLDQMKVTG FKDRFTGPMP KANGREYRIS KLKPPFGPSL RSAVVFQPDG
260 270 280 290 300
PGFKIDGHVV RWANWEFHMS FDVRAGLVIS LASIFDMDMN RYRQVLYKGH
310 320 330 340 350
LSEMFVPYMD PNDDWYFISY LDCGEFGCGQ TAVSLEPYTD CPPNAAFMDG
360 370 380 390 400
IFPGQDGTPT KISNVMCIFE KYAGDIMWRH TEAEVPGLKI TEVRPDVSLV
410 420 430 440 450
ARMVTTVGNY DYIIEYEFKP SGSIKMGVGL TGVLEVKPVE YVHTSEIKED
460 470 480 490 500
DIYGTIVADN TVGVNHDHFV TFRLDLDIDG TENSFVRTEL VTKRTPKSVN
510 520 530 540 550
TPRKSYWTTK RNTAKTEADA RVKLGLRAEE LVVVNPTKKT KHGNEVGYRL
560 570 580 590 600
LPGPASSPLL VQDDYPQIRA AFTNYNVWIT PYNKSEVWAS GLYADRSQGD
610 620 630 640 650
DTLAVWSQRD REIENKDIVM WYTVGFHHVP CQEDFPTMPT MFGGFELRPT
660 670
NFFEQNPVLK AKPFNLTTIP KCTTKNE
Length:677
Mass (Da):76,674
Last modified:June 28, 2011 - v1
Checksum:iA4A45980995368DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002684 Genomic DNA Translation: AEE31383.1
RefSeqiNP_174450.2, NM_102904.3
UniGeneiAt.51862

Genome annotation databases

EnsemblPlantsiAT1G31690.1; AT1G31690.1; AT1G31690
GeneIDi840056
GrameneiAT1G31690.1; AT1G31690.1; AT1G31690
KEGGiath:AT1G31690

Similar proteinsi

Entry informationi

Entry nameiF4IAX0_ARATH
AccessioniPrimary (citable) accession number: F4IAX0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health