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Protein

Glutathione S-transferase U21

Gene

GSTU21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to toxic substance Source: UniProtKB-KW
  • toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U21 (EC:2.5.1.18)
Short name:
AtGSTU21
Alternative name(s):
GST class-tau member 21
Gene namesi
Name:GSTU21
Ordered Locus Names:At1g78360
ORF Names:F3F9.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G78360.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135661 – 222Glutathione S-transferase U21Add BLAST222

Proteomic databases

PaxDbiF4IA73.

Expressioni

Gene expression databases

GenevisibleiF4IA73. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G78360.1.

Structurei

3D structure databases

ProteinModelPortaliF4IA73.
SMRiF4IA73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 83GST N-terminalAdd BLAST81
Domaini89 – 211GST C-terminalAdd BLAST123

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni13 – 14Glutathione bindingBy similarity2
Regioni40 – 41Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
InParanoidiF4IA73.
KOiK00799.
OMAiYSMESEC.
OrthoDBiEOG09360KSR.
PhylomeDBiF4IA73.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4IA73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEVILLGF WPSMFGMRTM IALEEKGVKY EYREEDVINN KSPLLLEMNP
60 70 80 90 100
IHKTIPVLIH NGKPVLESLI QIQYIDEVWS DNNSFLPSDP YHRAQALFWA
110 120 130 140 150
DFIDKKEQLY VCGRKTWATK GEELEAANKE FIEILKTLQC ELGEKPYFGG
160 170 180 190 200
DKFGFVDIVL IGFYSWFPAY QKFGNFSIEP ECLKLIAWGK RCMQRESVAK
210 220
ALPDSEKVVG YVLQLKKLYG IE
Length:222
Mass (Da):25,646
Last modified:June 28, 2011 - v1
Checksum:iED256E7956B86598
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013430 Genomic DNA. No translation available.
CP002684 Genomic DNA. Translation: AEE36097.1.
UniGeneiAt.66147.

Genome annotation databases

EnsemblPlantsiAT1G78360.1; AT1G78360.1; AT1G78360.
GrameneiAT1G78360.1; AT1G78360.1; AT1G78360.
KEGGiath:AT1G78360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013430 Genomic DNA. No translation available.
CP002684 Genomic DNA. Translation: AEE36097.1.
UniGeneiAt.66147.

3D structure databases

ProteinModelPortaliF4IA73.
SMRiF4IA73.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G78360.1.

Proteomic databases

PaxDbiF4IA73.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G78360.1; AT1G78360.1; AT1G78360.
GrameneiAT1G78360.1; AT1G78360.1; AT1G78360.
KEGGiath:AT1G78360.

Organism-specific databases

TAIRiAT1G78360.

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
InParanoidiF4IA73.
KOiK00799.
OMAiYSMESEC.
OrthoDBiEOG09360KSR.
PhylomeDBiF4IA73.

Miscellaneous databases

PROiF4IA73.

Gene expression databases

GenevisibleiF4IA73. AT.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSTUL_ARATH
AccessioniPrimary (citable) accession number: F4IA73
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.