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Protein

Glutathione S-transferase U21

Gene

GSTU21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U21 (EC:2.5.1.18)
Short name:
AtGSTU21
Alternative name(s):
GST class-tau member 21
Gene namesi
Name:GSTU21
Ordered Locus Names:At1g78360
ORF Names:F3F9.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi

Organism-specific databases

AraportiAT1G78360
TAIRilocus:2032025 AT1G78360

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135661 – 222Glutathione S-transferase U21Add BLAST222

Proteomic databases

PaxDbiF4IA73

Expressioni

Gene expression databases

ExpressionAtlasiF4IA73 differential
GenevisibleiF4IA73 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G78360.1

Structurei

3D structure databases

ProteinModelPortaliF4IA73
SMRiF4IA73
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 83GST N-terminalAdd BLAST81
Domaini89 – 211GST C-terminalAdd BLAST123

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni13 – 14Glutathione bindingBy similarity2
Regioni40 – 41Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
InParanoidiF4IA73
OMAiVAYEYRE
OrthoDBiEOG09360KSR
PhylomeDBiF4IA73

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

F4IA73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEVILLGF WPSMFGMRTM IALEEKGVKY EYREEDVINN KSPLLLEMNP
60 70 80 90 100
IHKTIPVLIH NGKPVLESLI QIQYIDEVWS DNNSFLPSDP YHRAQALFWA
110 120 130 140 150
DFIDKKEQLY VCGRKTWATK GEELEAANKE FIEILKTLQC ELGEKPYFGG
160 170 180 190 200
DKFGFVDIVL IGFYSWFPAY QKFGNFSIEP ECLKLIAWGK RCMQRESVAK
210 220
ALPDSEKVVG YVLQLKKLYG IE
Length:222
Mass (Da):25,646
Last modified:June 28, 2011 - v1
Checksum:iED256E7956B86598
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013430 Genomic DNA No translation available.
CP002684 Genomic DNA No translation available.

Entry informationi

Entry nameiGSTUL_ARATH
AccessioniPrimary (citable) accession number: F4IA73
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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