ID   F4HN54_PYRSN            Unreviewed;       379 AA.
AC   F4HN54;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=ATP-dependent DNA ligase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=PNA2_1142 {ECO:0000313|EMBL:AEC52058.1};
OS   Pyrococcus sp. (strain NA2).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=342949 {ECO:0000313|EMBL:AEC52058.1, ECO:0000313|Proteomes:UP000008293};
RN   [1] {ECO:0000313|EMBL:AEC52058.1, ECO:0000313|Proteomes:UP000008293}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA2 {ECO:0000313|EMBL:AEC52058.1,
RC   ECO:0000313|Proteomes:UP000008293};
RX   PubMed=21602357; DOI=10.1128/JB.05150-11;
RA   Lee H.S., Bae S.S., Kim M.S., Kwon K.K., Kang S.G., Lee J.H.;
RT   "Complete genome sequence of hyperthermophilic Pyrococcus sp. strain NA2,
RT   isolated from a deep-sea hydrothermal vent area.";
RL   J. Bacteriol. 193:3666-3667(2011).
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DR   EMBL; CP002670; AEC52058.1; -; Genomic_DNA.
DR   RefSeq; WP_013748612.1; NC_015474.1.
DR   AlphaFoldDB; F4HN54; -.
DR   STRING; 342949.PNA2_1142; -.
DR   GeneID; 10554618; -.
DR   KEGG; pyn:PNA2_1142; -.
DR   PATRIC; fig|342949.8.peg.1146; -.
DR   eggNOG; arCOG04218; Archaea.
DR   HOGENOM; CLU_061502_0_0_2; -.
DR   OrthoDB; 14524at2157; -.
DR   Proteomes; UP000008293; Chromosome.
DR   CDD; cd07894; Adenylation_RNA_ligase; 1.
DR   Gene3D; 1.20.58.2250; -; 1.
DR   Gene3D; 3.10.450.740; -; 1.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.70.3360; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   InterPro; IPR041596; Lig_Pab1020_C.
DR   InterPro; IPR021122; RNA_ligase_dom_REL/Rnl2.
DR   InterPro; IPR001072; RNA_ligase_Pab1020.
DR   NCBIfam; TIGR01209; RNA ligase; 1.
DR   Pfam; PF18330; Lig_C; 1.
DR   Pfam; PF09414; RNA_ligase; 1.
DR   PRINTS; PR01048; Y414FAMILY.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
PE   4: Predicted;
FT   DOMAIN          86..240
FT                   /note="RNA ligase"
FT                   /evidence="ECO:0000259|Pfam:PF09414"
FT   DOMAIN          253..374
FT                   /note="RNA ligase Pab1020 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18330"
SQ   SEQUENCE   379 AA;  43763 MW;  D0D05FE5D0E6238B CRC64;
     MVTSTFKDIL VRLGIPESRV ETLEMKGGII EDEFEGIRYL RFKDSAGKFR RGTVVFNEKT
     IVLGFPHIKR IVNLESGIRR TFKRGEFYVE EKVDGYNVRV VRVGDKILGI TRGGFICPFT
     TERITDFIPE EFFKDNPNLV LVGEMAGPES PYLVEGPPYV KEDIEFFLFD VQEINTGKSL
     PVEERLKIAE EYGIRHVEVF GKFTRDDIGE IREIIERLSE EGREGIVMKS PDMKKIVKYV
     TPFANINDIR IGAKVFYELP PGYFTSRISR LAFYIAENRI RGEEFNRIAL ELGKALLQPL
     VESIFDVEQE EEISEVFKVR VKRIETAYKM VTHFEKLGLK IEIVDIEEIK GGWKITFKRI
     YPDATEEIRE LIGGKAFVD
//