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F4HKU8 (F4HKU8_PYRSN) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904

Short name=PEPC HAMAP-Rule MF_01904
Short name=PEPCase HAMAP-Rule MF_01904
EC=4.1.1.31 HAMAP-Rule MF_01904
Gene names
Name:ppcA HAMAP-Rule MF_01904
Ordered Locus Names:PNA2_0537 EMBL AEC51453.1
OrganismPyrococcus sp. (strain NA2) [Complete proteome] [HAMAP] EMBL AEC51453.1
Taxonomic identifier342949 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family. HAMAP-Rule MF_01904

Sequences

Sequence LengthMass (Da)Tools
F4HKU8 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: BC4CF3D86D84A4CD

FASTA47054,363
        10         20         30         40         50         60 
MIPRIMSTQH PDNYSIPFFA SSPVLGGDDE ITEAFYAFSV LGADEQMWDF EGKEVDEFVV 

        70         80         90        100        110        120 
KKLLERYSMF FKKVILGKDV RITPRVPNPS VEKAEAKLLI ETLQGITRAA DYAKVFYEDD 

       130        140        150        160        170        180 
IAPIFEVILP MTTSLAEIER VYMLYKRIVE LANEVIYDVT VREWIGDFYP KEIGVIPLFE 

       190        200        210        220        230        240 
TKVALLKSAK IVKDYISRRR NIEYMRVFFA RSDPAMNYGL ISAVTYVKKA LYEMFKVEDS 

       250        260        270        280        290        300 
LSIPIYPIIG VGGPPFRGGM RPDNVENVVR EYPSVQTYTI QSSFKYDHPT KEVVKAVEFV 

       310        320        330        340        350        360 
KSTKRREPHF VDIPDFIQLY EVEYQRQIKI LAPHIRRVVT RIPDRRRRKL HIGLFGYSRR 

       370        380        390        400        410        420 
IGDMALPRAI KFTASLYSIG IPPELLALNA LSDKQLDIVS EYYKNVYEDL EFAMRFFSFK 

       430        440        450        460        470 
VAESVGLKEL VERIKEFKPE INEEYVSEAE QVFRGQGDVI KLAQIRGFLG 

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References

[1]"Complete genome sequence of hyperthermophilic Pyrococcus sp. strain NA2, isolated from a deep-sea hydrothermal vent area."
Lee H.S., Bae S.S., Kim M.S., Kwon K.K., Kang S.G., Lee J.H.
J. Bacteriol. 193:3666-3667(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NA2 EMBL AEC51453.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002670 Genomic DNA. Translation: AEC51453.1.
RefSeqYP_004423457.1. NC_015474.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEC51453; AEC51453; PNA2_0537.
GeneID10554004.
KEGGpyn:PNA2_0537.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.
OMADEYMPDY.

Enzyme and pathway databases

BioCycPSP342949:GI74-551-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF4HKU8_PYRSN
AccessionPrimary (citable) accession number: F4HKU8
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 14, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)