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F4HHI5

- F4HHI5_MYCHM

UniProt

F4HHI5 - F4HHI5_MYCHM

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Protein
Elongation factor Tu
Gene
tuf, SRH_02965
Organism
Mycoplasma hyorhinis (strain MCLD)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi25 – 328GTP By similarityUniRule annotation
Nucleotide bindingi87 – 915GTP By similarityUniRule annotation
Nucleotide bindingi142 – 1454GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMHYO936139:GLHH-574-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:SRH_02965Imported
    OrganismiMycoplasma hyorhinis (strain MCLD)Imported
    Taxonomic identifieri936139 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000008738: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F4HHI5-1 [UniParc]FASTAAdd to Basket

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    MAVQKPGAKK DFDRSKEHIN IGTIGHVDHG KTTLTAAIST VLSKKGLAEA    50
    KDYASIDAAP EEKARGITIN TAHIEYSTDK RHYAHVDCPG HADYIKNMIT 100
    GAAQMDGAIL VVAATDGPMP QTREHILLSK QVGVPKIVVF LNKVDMLQGE 150
    EEMVDLVEVE VRELLSSYDF DGDNTPIVRG SAKGALEGKP EWEAKILELM 200
    DAVDTYIDSP VRELDKPFLM AVEDVFTITG RGTVATGKVE RGQVKLNEEV 250
    EIVGYKAEPK KTVVTGIEMF NKNLQSAMAG DNAGVLLRGV NRDEIERGQV 300
    IAKPKTIVPH TTFKAAIYVL KKEEGGRHTP FFPNYKPQFY FRTTDVTGGV 350
    KFEQGVEMVK PGDNVNLTVE LIAPIAVEQG TKFSIREGGR TVGAGTVTEI 400
    VK 402
    Length:402
    Mass (Da):43,845
    Last modified:June 28, 2011 - v1
    Checksum:i84B31481B62B2135
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002669 Genomic DNA. Translation: AEC46135.1.
    RefSeqiYP_005905187.1. NC_017519.1.

    Genome annotation databases

    EnsemblBacteriaiAEC46135; AEC46135; SRH_02965.
    GeneIDi12495752.
    KEGGimhm:SRH_02965.
    PATRICi54238500. VBIMycHyo178314_0578.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002669 Genomic DNA. Translation: AEC46135.1 .
    RefSeqi YP_005905187.1. NC_017519.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEC46135 ; AEC46135 ; SRH_02965 .
    GeneIDi 12495752.
    KEGGi mhm:SRH_02965.
    PATRICi 54238500. VBIMycHyo178314_0578.

    Phylogenomic databases

    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci MHYO936139:GLHH-574-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome analysis of a Mycoplasma hyorhinis strain derived from a primary human melanoma cell line."
      Kornspan J.D., Lysnyansky I., Kahan T., Herrmann R., Rottem S., Nir-Paz R.
      J. Bacteriol. 193:4543-4544(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MCLDImported.

    Entry informationi

    Entry nameiF4HHI5_MYCHM
    AccessioniPrimary (citable) accession number: F4HHI5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: June 11, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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