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Protein

Elongation factor Tu

Gene

tuf

Organism
Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi83 – 87GTPUniRule annotation5
Nucleotide bindingi138 – 141GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Celf_0998Imported
OrganismiCellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)Imported
Taxonomic identifieri590998 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesCellulomonadaceaeCellulomonas
Proteomesi
  • UP000008460 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiF4H1W5.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi590998.Celf_0998.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
KOiK02358.
OMAiYGHIDCP.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F4H1W5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKAKFERTK PHVNIGTIGH VDHGKTTLTA AISKVLHDKY PDLNPFTPFD
60 70 80 90 100
EIDKAPEEKQ RGITINIAHV EYQTEKRHYA HVDAPGHADY IKNMITGAAQ
110 120 130 140 150
MDGAILVVAA TDGPMAQTRE HVLLARQVGV PYLLVALNKS DVVDDEEILE
160 170 180 190 200
LVEVEVRELL SSQGFAGDDV PVVRVSGLKA LEGDPVWVKS VEDLLDAVDE
210 220 230 240 250
NVPDPVRDID KPFLMPIEDV FTITGRGTVV TGRVERGQLK VNEEVEIVGI
260 270 280 290 300
KEKAIKTTVT GVEMFRKLLD YAEAGENVGL LLRGTKREEV ERGQVVVKPG
310 320 330 340 350
SITPHTEFEG QVYILAKDEG GRHNPFYGNY RPQFYFRTTD VTGVITLPEG
360 370 380 390
TEMVMPGDNT EIHVNLIQPI AMEEGLGFAI REGGRTVGSG RVTKILK
Length:397
Mass (Da):43,716
Last modified:June 28, 2011 - v1
Checksum:iBF9CD47569F93B45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002666 Genomic DNA. Translation: AEE45135.1.
RefSeqiWP_013770163.1. NC_015514.1.

Genome annotation databases

EnsemblBacteriaiAEE45135; AEE45135; Celf_0998.
KEGGicfi:Celf_0998.

Similar proteinsi

Entry informationi

Entry nameiF4H1W5_CELFA
AccessioniPrimary (citable) accession number: F4H1W5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 27, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported