Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F4GYB0

- F4GYB0_CELFA

UniProt

F4GYB0 - F4GYB0_CELFA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable DNA ligase

Gene

lig

Organism
Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Note: Divalent metal cations.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei215 – 2151ATPUniRule annotation
Active sitei217 – 2171N6-AMP-lysine intermediateUniRule annotation
Binding sitei222 – 2221ATPUniRule annotation
Binding sitei237 – 2371ATPUniRule annotation
Binding sitei266 – 2661ATPUniRule annotation
Binding sitei304 – 3041ATPUniRule annotation
Binding sitei375 – 3751ATPUniRule annotation
Binding sitei381 – 3811ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA biosynthetic process Source: InterPro
  4. DNA ligation involved in DNA repair Source: InterPro
  5. DNA recombination Source: UniProtKB-HAMAP
  6. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCFIM590998:GJFK-1788-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligUniRule annotation
Ordered Locus Names:Celf_1767Imported
OrganismiCellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)Imported
Taxonomic identifieri590998 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeCellulomonadaceaeCellulomonas
ProteomesiUP000008460: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK01971.
OMAiVPIVIPY.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4GYB0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLADVAATS AAVAATRSRL AKRALLVDVL RRAEPEDVPV VARYLAGELR
60 70 80 90 100
QRRTGLGWRS LASLPGPAAG PSLTVAAVDA AFAHMAQLEG PGSATERSRL
110 120 130 140 150
AAELFAAATG PEQALLRGLV SGELRQGALD ALLLDALAEA AGVPPDAVRR
160 170 180 190 200
AAMLAGATEP VAVAALGAAD PQAALEALAA FTLTVGRPVR PMLAQSAPDV
210 220 230 240 250
ATAVAGLGGG PVVVDTKLDG IRIQVHRTAD DVRVYTRSLD DITARVPEIV
260 270 280 290 300
EAVRAVPAST LVLDGEALVV DDTGRPVPFQ DTAARSATKD ADVAAAVRLT
310 320 330 340 350
PFFFDCLHVD GRDLLDSPLT ERLAVLDATV GPAAVTRLVT ADPDAAQDWF
360 370 380 390 400
ARVVAAGQEG VVVKAADAPY EAGRRGAAWV KVKPRHTLDL VVLAVERGSG
410 420 430 440 450
RRSGWLSNIH LGARDGHGGF VMLGKTFKGM TDEMLAQQTE RFRELEVSDD
460 470 480 490 500
GWTVTVRPEQ VVEIAFDGVQ RSTRYPGGVA LRFARVVRYR DDKSAAQADT
510
IDAVRALHAP
Length:510
Mass (Da):53,499
Last modified:June 28, 2011 - v1
Checksum:i184E15B1AE0A3AA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002666 Genomic DNA. Translation: AEE45899.1.
RefSeqiYP_004453286.1. NC_015514.1.

Genome annotation databases

EnsemblBacteriaiAEE45899; AEE45899; Celf_1767.
GeneIDi10592548.
KEGGicfi:Celf_1767.
PATRICi54614460. VBICelFim18861_1770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002666 Genomic DNA. Translation: AEE45899.1 .
RefSeqi YP_004453286.1. NC_015514.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEE45899 ; AEE45899 ; Celf_1767 .
GeneIDi 10592548.
KEGGi cfi:Celf_1767.
PATRICi 54614460. VBICelFim18861_1770.

Phylogenomic databases

KOi K01971.
OMAi VPIVIPY.

Enzyme and pathway databases

BioCyci CFIM590998:GJFK-1788-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Cellulomonas fimi ATCC 484."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Mead D., Brumm P., Woyke T.
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547Imported.

Entry informationi

Entry nameiF4GYB0_CELFA
AccessioniPrimary (citable) accession number: F4GYB0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 26, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3