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F4GYB0 (F4GYB0_CELFA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Celf_1767 EMBL AEE45899.1
OrganismCellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) [Complete proteome] [HAMAP] EMBL AEE45899.1
Taxonomic identifier590998 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeCellulomonadaceaeCellulomonas

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196 HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2171N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2151ATP By similarity HAMAP-Rule MF_00407
Binding site2221ATP By similarity HAMAP-Rule MF_00407
Binding site2371ATP By similarity HAMAP-Rule MF_00407
Binding site2661ATP By similarity HAMAP-Rule MF_00407
Binding site3041ATP By similarity HAMAP-Rule MF_00407
Binding site3751ATP By similarity HAMAP-Rule MF_00407
Binding site3811ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
F4GYB0 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 184E15B1AE0A3AA8

FASTA51053,499
        10         20         30         40         50         60 
MLLADVAATS AAVAATRSRL AKRALLVDVL RRAEPEDVPV VARYLAGELR QRRTGLGWRS 

        70         80         90        100        110        120 
LASLPGPAAG PSLTVAAVDA AFAHMAQLEG PGSATERSRL AAELFAAATG PEQALLRGLV 

       130        140        150        160        170        180 
SGELRQGALD ALLLDALAEA AGVPPDAVRR AAMLAGATEP VAVAALGAAD PQAALEALAA 

       190        200        210        220        230        240 
FTLTVGRPVR PMLAQSAPDV ATAVAGLGGG PVVVDTKLDG IRIQVHRTAD DVRVYTRSLD 

       250        260        270        280        290        300 
DITARVPEIV EAVRAVPAST LVLDGEALVV DDTGRPVPFQ DTAARSATKD ADVAAAVRLT 

       310        320        330        340        350        360 
PFFFDCLHVD GRDLLDSPLT ERLAVLDATV GPAAVTRLVT ADPDAAQDWF ARVVAAGQEG 

       370        380        390        400        410        420 
VVVKAADAPY EAGRRGAAWV KVKPRHTLDL VVLAVERGSG RRSGWLSNIH LGARDGHGGF 

       430        440        450        460        470        480 
VMLGKTFKGM TDEMLAQQTE RFRELEVSDD GWTVTVRPEQ VVEIAFDGVQ RSTRYPGGVA 

       490        500        510 
LRFARVVRYR DDKSAAQADT IDAVRALHAP 

« Hide

References

[1]"Complete sequence of Cellulomonas fimi ATCC 484."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Mead D., Brumm P., Woyke T.
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002666 Genomic DNA. Translation: AEE45899.1.
RefSeqYP_004453286.1. NC_015514.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEE45899; AEE45899; Celf_1767.
GeneID10592548.
KEGGcfi:Celf_1767.
PATRIC54614460. VBICelFim18861_1770.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01971.
OMAVPIVIPY.

Enzyme and pathway databases

BioCycCFIM590998:GJFK-1788-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4GYB0_CELFA
AccessionPrimary (citable) accession number: F4GYB0
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)