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F4GQK3

- F4GQK3_PUSST

UniProt

F4GQK3 - F4GQK3_PUSST

Protein

Alanine racemase

Gene

PT7_3361

Organism
Pusillimonas sp. (strain T7-7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei61 – 611Proton acceptor; specific for D-alanineUniRule annotation
    Active sitei283 – 2831Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei331 – 3311Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPSP1007105:GJAF-3411-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:PT7_3361Imported
    OrganismiPusillimonas sp. (strain T7-7)Imported
    Taxonomic identifieri1007105 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaePusillimonas
    ProteomesiUP000008737: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei61 – 611N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF4GQK3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiTSADEWI.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F4GQK3-1 [UniParc]FASTAAdd to Basket

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    MTSAIPVQTP IQARSKSGHA CHNSPLALID HTAIRHNLNR LRQLLAYPKT    50
    LPTPLIWAVA KADAYGHTLE HAYAGLCEAD GLAVLTLDEA RHCRSLGWTG 100
    PILAMSAQIT QAALEDPILY PLHLIIDHQE QLAAIQSLRP PFSPHVWLRY 150
    RGRLNHAGFD QAGYKSAYAS LQSGLRDGRL AELGHLQHYA TAEEAEPMLA 200
    ERQAFQLLIE GLPGPVCTDN SAALLSDHSG AALTSWVRSG IALYGISPLA 250
    GLNGKDLGLR PAMVLQAPLY GFQTLQAGDS LGYGSTFLAS RKTRVGLVRC 300
    GYAHGYPRSI PEGCEVMVTG RMATIIGRVS MDTLTIDLTD HPDAGYGTVV 350
    TLWGTPELPI EVVAAQANTI PAQLCTALTE RVPRQSVS 388
    Length:388
    Mass (Da):41,750
    Last modified:June 28, 2011 - v1
    Checksum:iD4603A8D9D8EBA3F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002663 Genomic DNA. Translation: AEC21901.1.
    RefSeqiWP_013744420.1. NC_015458.1.
    YP_004418525.1. NC_015458.1.

    Genome annotation databases

    EnsemblBacteriaiAEC21901; AEC21901; PT7_3361.
    GeneIDi10604042.
    KEGGiput:PT7_3361.
    PATRICi54560998. VBIPusSp189076_3314.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002663 Genomic DNA. Translation: AEC21901.1 .
    RefSeqi WP_013744420.1. NC_015458.1.
    YP_004418525.1. NC_015458.1.

    3D structure databases

    ProteinModelPortali F4GQK3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEC21901 ; AEC21901 ; PT7_3361 .
    GeneIDi 10604042.
    KEGGi put:PT7_3361.
    PATRICi 54560998. VBIPusSp189076_3314.

    Phylogenomic databases

    KOi K01775.
    OMAi TSADEWI.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PSP1007105:GJAF-3411-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Pusillimonas sp. T7-7, a cold-tolerant diesel oil-degrading bacterium isolated from the Bohai Sea in China."
      Cao B., Ma T., Ren Y., Ren Y., Li G., Li P., Guo X., Ding P., Feng L.
      J. Bacteriol. 193:4021-4022(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: T7-7Imported.
    2. "Genome Announcement Complete Genome Sequence of Pusillimonas sp. T7-7, a novel species isolated from the Bohai Sea, China."
      Cao B., Ma T., Li P., Jiang L., Li Y., Guo X., Feng L.
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: T7-7.

    Entry informationi

    Entry nameiF4GQK3_PUSST
    AccessioniPrimary (citable) accession number: F4GQK3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3