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Protein

3-octaprenyl-4-hydroxybenzoate carboxy-lyase

Gene

ubiD

Organism
Pusillimonas sp. (strain T7-7)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.SAAS annotation

Catalytic activityi

A 4-hydroxy-3-polyprenylbenzoate = a 2-polyprenylphenol + CO2.UniRule annotationSAAS annotation

Cofactori

Mn2+UniRule annotationSAAS annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi177ManganeseUniRule annotation1
Metal bindingi243ManganeseUniRule annotation1
Active sitei314Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotationSAAS annotation, Lyase
Biological processUbiquinone biosynthesisUniRule annotationSAAS annotation
LigandFlavoprotein, FMNUniRule annotationSAAS annotation, ManganeseUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPSP1007105:G1GWE-2023-MONOMER
UniPathwayiUPA00232

Names & Taxonomyi

Protein namesi
Recommended name:
3-octaprenyl-4-hydroxybenzoate carboxy-lyaseUniRule annotationSAAS annotation (EC:4.1.1.98UniRule annotation)
Alternative name(s):
Polyprenyl p-hydroxybenzoate decarboxylaseUniRule annotation
Gene namesi
Name:ubiDUniRule annotation
Ordered Locus Names:PT7_2058Imported
OrganismiPusillimonas sp. (strain T7-7)Imported
Taxonomic identifieri1007105 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaePusillimonas
Proteomesi
  • UP000008737 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Peripheral membrane protein UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Subunit structurei

Homohexamer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi1007105.PT7_2058

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni180 – 182Prenyl-FMN bindingUniRule annotation3
Regioni194 – 196Prenyl-FMN bindingUniRule annotation3
Regioni199 – 200Prenyl-FMN bindingUniRule annotation2

Sequence similaritiesi

Belongs to the UbiD family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105D3H Bacteria
COG0043 LUCA
KOiK03182
OMAiIDATNKW
OrthoDBiPOG091H05QI

Family and domain databases

HAMAPiMF_01636 UbiD, 1 hit
InterProiView protein in InterPro
IPR002830 UbiD
IPR023677 UbiD_bacteria
PfamiView protein in Pfam
PF01977 UbiD, 1 hit
TIGRFAMsiTIGR00148 TIGR00148, 2 hits

Sequencei

Sequence statusi: Complete.

F4GQ88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYRDLRDFI AQLERTGELK RVSLPVSTEL EMTEISDRVL RAGGPALLFE
60 70 80 90 100
QATHNGAAST MPVLTNLFGT PQRVAWGMGA DNVSALRTTG ELLASLREPE
110 120 130 140 150
PPRGLRNALA TVSMLKNALW DMSPKTVKNA PCQEIVLEGD DVDLNQIPLQ
160 170 180 190 200
RCWPGDVAPL LTWGLVITRG PNAKRQNLGI YRQQLIGRNK LIMRWLSHRG
210 220 230 240 250
GALDFRDHAL AHPGTPFPVA VALGADPATI LGAVTPVPDS LSEYQFAGLL
260 270 280 290 300
RGSRTEVTQA LGSTLSVPAY AEIVLEGHLL PSSDPRATKP VPPEGVAAPV
310 320 330 340 350
DASYEMALEG PYGDHTGYYN EQDWFPVFTV ERITMRRNPI YHSTYTGKPP
360 370 380 390 400
DEPAVLGVAL NEVFVPLLKR QLPEIVDFYL PPEGCSYRLA VVSMRKQYAG
410 420 430 440 450
HAKRVMFGLW SILRQFMYTK FIVVVDDDID VRDWKEVVWA MTTRMDPVRD
460 470 480 490 500
TVLVENTPID YLDFASPVSG LGGKMGLDAT NKWPGESTRE WGTPIVMDQN
510
IKARVDAMWN ELGL
Length:514
Mass (Da):56,940
Last modified:June 28, 2011 - v1
Checksum:i96F15EC7CBE0FD49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002663 Genomic DNA Translation: AEC20598.1
RefSeqiWP_013743132.1, NC_015458.1

Genome annotation databases

EnsemblBacteriaiAEC20598; AEC20598; PT7_2058
KEGGiput:PT7_2058

Similar proteinsi

Entry informationi

Entry nameiF4GQ88_PUSST
AccessioniPrimary (citable) accession number: F4GQ88
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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