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F4GMB5 (F4GMB5_PUSST) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:PT7_0480 EMBL AEC19020.1
OrganismPusillimonas sp. (strain T7-7) [Complete proteome] [HAMAP] EMBL AEC19020.1
Taxonomic identifier1007105 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaePusillimonas

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3191Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue441N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F4GMB5 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 6BAD2B1C1F0D1321

FASTA37640,016
        10         20         30         40         50         60 
MPRPISATVS VSSLSHNLQR VANGLQQSCN AAKPLRPRVW AVIKANAYGH GIDQAVQGFA 

        70         80         90        100        110        120 
QADGLAMLDL NEAVRCRELG WTKPILLLEG FFEPGDIAVL DEYCLTTSLH CQEQLEMLAA 

       130        140        150        160        170        180 
AKPANPLNAF VKLNVGMNRL GFSEYAFPDA YRQAQQLQQQ GILASVGKMS HFARADDSPV 

       190        200        210        220        230        240 
TTTQQLQVFN RMTQGLPGPF SVCNSAASLT AGLWTTVSSD EEQWVRPGIC LYGSSPFEDR 

       250        260        270        280        290        300 
LPDALGLRPA MTLAAQLISV REIPRGAGVG YGHVFTASDA MRIGIVACGY ADGYPRHAGT 

       310        320        330        340        350        360 
GTPICVDGVR TRLVGRVSMD MLAVDLTPVP QAGVGSPVVL WGEGGPSVDE VAQAAGTIGY 

       370 
ELLCAVAPRV PRVIAV 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Pusillimonas sp. T7-7, a cold-tolerant diesel oil-degrading bacterium isolated from the Bohai Sea in China."
Cao B., Ma T., Ren Y., Ren Y., Li G., Li P., Guo X., Ding P., Feng L.
J. Bacteriol. 193:4021-4022(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T7-7 EMBL AEC19020.1.
[2]"Genome Announcement Complete Genome Sequence of Pusillimonas sp. T7-7, a novel species isolated from the Bohai Sea, China."
Cao B., Ma T., Li P., Jiang L., Li Y., Guo X., Feng L.
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: T7-7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002663 Genomic DNA. Translation: AEC19020.1.
RefSeqYP_004415644.1. NC_015458.1.

3D structure databases

ProteinModelPortalF4GMB5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEC19020; AEC19020; PT7_0480.
GeneID10605098.
KEGGput:PT7_0480.
PATRIC54555223. VBIPusSp189076_0475.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMASRLGLWH.

Enzyme and pathway databases

BioCycPSP1007105:GJAF-489-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4GMB5_PUSST
AccessionPrimary (citable) accession number: F4GMB5
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 9, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)