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Protein

Superoxide dismutase

Gene

Mcup_0395

Organism
Metallosphaera cuprina (strain Ar-4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciMCUP1006006:GHTI-406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mcup_0395Imported
OrganismiMetallosphaera cuprina (strain Ar-4)Imported
Taxonomic identifieri1006006 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
ProteomesiUP000007812 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1006006.Mcup_0395.

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

KOiK04564.
OMAiVNWDDVE.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F4FZS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSISFKKF ELPPLPYKLD ALEPYISKDI IDVHYNGHHK GYVNGINTFM
60 70 80 90 100
DRFNKVIKGE VQAGQYDIQG LMRGIVFNVN GHKLHALYWD NMAPAGKGGG
110 120 130 140 150
QPGGALADLI VKQYGSYERF KQIFTETANS LPGTGWTVLY YDTENGNLEI
160 170 180 190 200
MTFENHFMNH IAELPILLIL DEFEHAYYLQ YKNKRADYVN NWWNVVNWEY
210
SDKKLQKYMK
Length:210
Mass (Da):24,333
Last modified:June 28, 2011 - v1
Checksum:i5BA342E6C83EFF20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002656 Genomic DNA. Translation: AEB94503.1.
RefSeqiWP_013737001.1. NC_015435.1.
YP_004408987.1. NC_015435.1.

Genome annotation databases

EnsemblBacteriaiAEB94503; AEB94503; Mcup_0395.
GeneIDi10492589.
KEGGimcn:Mcup_0395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002656 Genomic DNA. Translation: AEB94503.1.
RefSeqiWP_013737001.1. NC_015435.1.
YP_004408987.1. NC_015435.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1006006.Mcup_0395.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEB94503; AEB94503; Mcup_0395.
GeneIDi10492589.
KEGGimcn:Mcup_0395.

Phylogenomic databases

KOiK04564.
OMAiVNWDDVE.

Enzyme and pathway databases

BioCyciMCUP1006006:GHTI-406-MONOMER.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Metallosphaera cuprina, a metal sulfide-oxidizing archaeon from a hot spring."
    Liu L.J., You X.Y., Zheng H., Wang S., Jiang C.Y., Liu S.J.
    J. Bacteriol. 193:3387-3388(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ar-4Imported.

Entry informationi

Entry nameiF4FZS4_METCR
AccessioniPrimary (citable) accession number: F4FZS4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 24, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.