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Protein

Superoxide dismutase

Gene

Mcup_0395

Organism
Metallosphaera cuprina (strain Ar-4)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi34Divalent metal cationUniRule annotation1
Metal bindingi85Divalent metal cationUniRule annotation1
Metal bindingi171Divalent metal cationUniRule annotation1
Metal bindingi175Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMCUP1006006:G1GWB-409-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mcup_0395Imported
OrganismiMetallosphaera cuprina (strain Ar-4)Imported
Taxonomic identifieri1006006 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
Proteomesi
  • UP000007812 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1006006.Mcup_0395

Structurei

3D structure databases

SMRiF4FZS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 93Sod_Fe_NInterPro annotationAdd BLAST85
Domaini102 – 201Sod_Fe_CInterPro annotationAdd BLAST100

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04147 Archaea
COG0605 LUCA
KOiK04564
OMAiKWGSFDK
OrthoDBiPOG093Z0AKF

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

F4FZS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSISFKKF ELPPLPYKLD ALEPYISKDI IDVHYNGHHK GYVNGINTFM
60 70 80 90 100
DRFNKVIKGE VQAGQYDIQG LMRGIVFNVN GHKLHALYWD NMAPAGKGGG
110 120 130 140 150
QPGGALADLI VKQYGSYERF KQIFTETANS LPGTGWTVLY YDTENGNLEI
160 170 180 190 200
MTFENHFMNH IAELPILLIL DEFEHAYYLQ YKNKRADYVN NWWNVVNWEY
210
SDKKLQKYMK
Length:210
Mass (Da):24,333
Last modified:June 28, 2011 - v1
Checksum:i5BA342E6C83EFF20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002656 Genomic DNA Translation: AEB94503.1
RefSeqiWP_013737001.1, NC_015435.1

Genome annotation databases

EnsemblBacteriaiAEB94503; AEB94503; Mcup_0395
GeneIDi10492589
KEGGimcn:Mcup_0395
PATRICifig|1006006.8.peg.396

Similar proteinsi

Entry informationi

Entry nameiF4FZS4_METCR
AccessioniPrimary (citable) accession number: F4FZS4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health