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F4FP70 (F4FP70_STAAU) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
ORF Names:SAT0131_01802 EMBL AEB88785.1
OrganismStaphylococcus aureus subsp. aureus T0131 EMBL AEB88785.1
Taxonomic identifier1006543 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339 SAAS SAAS000023

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339 SAAS SAAS000023

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339 SAAS SAAS000023.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 255ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding156 – 1605ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding173 – 18917ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1291Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1871Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1891Magnesium By similarity HAMAP-Rule MF_00339
Binding site1641Substrate By similarity HAMAP-Rule MF_00339
Binding site2451Substrate By similarity HAMAP-Rule MF_00339
Binding site2511Substrate By similarity HAMAP-Rule MF_00339
Binding site2541Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
F4FP70 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 1FAE41C0BA7CA7F1

FASTA32234,840
        10         20         30         40         50         60 
MKKIAVLTSG GDSPGMNAAV RAVVRTAIYN EIEVYGVYHG YQGLLNDDIH KLELGSVGDT 

        70         80         90        100        110        120 
IQRGGTFLYS ARCPEFKEQE VRKVAIENLR KRGIEGLVVI GGDGSYRGAQ RISEECKEIQ 

       130        140        150        160        170        180 
TIGIPGTIDN DINGTDFTIG FDTALNTIIG LVDKIRDTAS SHARTFIIEA MGRDCGDLAL 

       190        200        210        220        230        240 
WAGLSVGAET IVVPEVKTDI KEIADKIEQG IKRGKKHSIV LVAEGCMTAQ DCQKELSQYI 

       250        260        270        280        290        300 
NVDNRVSVLG HVQRGGSPTG ADRVLASRLG GYAVDLLMQG ETAKGVGIKN NKIVATSFDE 

       310        320 
IFDGKDHKFD YSLYELANKL SI

« Hide

References

[1]"Complete genome sequence of Staphylococcus aureus T0131, an ST239-MRSA-SCCmec type III clone isolated in China."
Li Y., Cao B., Zhang Y., Zhou J., Yang B., Wang L.
J. Bacteriol. 193:3411-3412(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: T0131 EMBL AEB88785.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002643 Genomic DNA. Translation: AEB88785.1.
RefSeqYP_005752951.1. NC_017347.1.

3D structure databases

ProteinModelPortalF4FP70.
SMRF4FP70. Positions 1-322.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB88785; AEB88785; SAT0131_01802.
GeneID12339351.
KEGGsut:SAT0131_01802.
PATRIC54324256. VBIStaAur188048_1668.

Phylogenomic databases

KOK00850.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4FP70_STAAU
AccessionPrimary (citable) accession number: F4FP70
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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