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F4FB98 (F4FB98_VERMA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site331Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2611Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1311Substrate By similarity HAMAP-Rule MF_01201
Binding site3091Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue331N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F4FB98 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 8A761BAFF5140175

FASTA37239,264
        10         20         30         40         50         60 
MWQAEVRVDL DAIRENVDRM RAGTSAELMA VVKADGYGHG MVPAARAALD AGATWLGVCT 

        70         80         90        100        110        120 
LDEALALRAA GIDAPVLAWL LAPGLPLHTG VAADVDLGVA SLPQLDEAVE ASRRAQRPAR 

       130        140        150        160        170        180 
VHLKIDTGLS RNGATVADWP ALLDAAAKAQ ADGLVEVVGV WSHFVYADMP GHPTTDRQLA 

       190        200        210        220        230        240 
VFHEGLAMVE RAGLRPRYRH LANSAATLTR PDTHFDLVRP GLAVYGLSPV AGETHGLRPA 

       250        260        270        280        290        300 
MTARARVMLT KRVPAGTGVS YGHTYTTERD ANLAVVPLGY ADGVPRHASN TGPVQLGGRR 

       310        320        330        340        350        360 
RTISGRVCMD QFVLDCGDDP VAAGDVATLF GSGADGEPTA DDWAEAVGTI NYEIVTRFGS 

       370 
SRVPRVYDGT DS 

« Hide

References

[1]"Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032."
Roh H., Uguru G.C., Ko H.J., Kim S., Kim B.Y., Goodfellow M., Bull A.T., Kim K.H., Bibb M.J., Choi I.G., Stach J.E.
J. Bacteriol. 193:3391-3392(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AB-18-032 EMBL AEB47243.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002638 Genomic DNA. Translation: AEB47243.1.
RefSeqYP_004407843.1. NC_015434.1.

3D structure databases

ProteinModelPortalF4FB98.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEB47243; AEB47243; VAB18032_00795.
GeneID10454026.
KEGGvma:VAB18032_00795.
PATRIC54478965. VBIVerMar92278_5321.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycVMAR263358:GI1P-5263-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF4FB98_VERMA
AccessionPrimary (citable) accession number: F4FB98
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)