Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F4F695

- F4F695_VERMA

UniProt

F4F695 - F4F695_VERMA

Protein

Probable DNA ligase

Gene

ligB

Organism
Verrucosispora maris (strain AB-18-032)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei209 – 2091ATPUniRule annotation
    Active sitei211 – 2111N6-AMP-lysine intermediateUniRule annotation
    Binding sitei216 – 2161ATPUniRule annotation
    Binding sitei231 – 2311ATPUniRule annotation
    Binding sitei260 – 2601ATPUniRule annotation
    Binding sitei322 – 3221ATPUniRule annotation
    Binding sitei394 – 3941ATPUniRule annotation
    Binding sitei400 – 4001ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciVMAR263358:GI1P-4863-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligBImported
    Synonyms:ligUniRule annotation
    Ordered Locus Names:VAB18032_28881Imported
    OrganismiVerrucosispora maris (strain AB-18-032)Imported
    Taxonomic identifieri263358 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeVerrucosispora
    ProteomesiUP000008308: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK01971.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 2 hits.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F4F695-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRFLDLAATS AAVAATSGRR AKVELLAEAL RRLDPVEIAA GAGWLAGELR    50
    QRQTGVGWAG LRDLPPPAAE PTLTVGAVDA AIDAIAAVHG SGSQARRRAL 100
    VHSLYAAATA DEQRLLTGLF LGELRHGAQA GLLADAIARA AGVPVAAVRR 150
    ALLLAGDLRE VAVAALAGGA AALAGFGLRV GRPLAPMLAQ SASSVDEALA 200
    ATGTPAVVDV KLDGIRIQVH RSGSDIAVFT RSLDDITARV PEVVAAVRAL 250
    PARELVLDGE AIGLDETGRP LPFQQTSSAA ARRGGSAGAR STGGPTAAAP 300
    VAPAVRAAAA STGTTVLTPY FFDLLHLDGT DLIDAPGRER WAVLRGTVDA 350
    GLLVGRMEVD EPQRAGEAFA AALDAGQEGV VVKAPDAPYE AGRRGAAWIK 400
    VKPRHTLDLV VLAVEWGSGR RTGWLSNLHL GARDPRTGEF VMLGKTFKGL 450
    TDDLLRWQTE RFLGLAVERG DWVVRVRPEQ VVEIAFDGVQ TSSRYPGGVA 500
    LRFARVVRYR EDKSAAEADT IDTVRAIHAG RPPAAPSP 538
    Length:538
    Mass (Da):56,037
    Last modified:June 28, 2011 - v1
    Checksum:i6E3443C358FB2881
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002638 Genomic DNA. Translation: AEB46847.1.
    RefSeqiYP_004407447.1. NC_015434.1.

    Genome annotation databases

    EnsemblBacteriaiAEB46847; AEB46847; VAB18032_28881.
    GeneIDi10453626.
    KEGGivma:VAB18032_28881.
    PATRICi54478133. VBIVerMar92278_4913.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002638 Genomic DNA. Translation: AEB46847.1 .
    RefSeqi YP_004407447.1. NC_015434.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEB46847 ; AEB46847 ; VAB18032_28881 .
    GeneIDi 10453626.
    KEGGi vma:VAB18032_28881.
    PATRICi 54478133. VBIVerMar92278_4913.

    Phylogenomic databases

    KOi K01971.

    Enzyme and pathway databases

    BioCyci VMAR263358:GI1P-4863-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 2 hits.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032."
      Roh H., Uguru G.C., Ko H.J., Kim S., Kim B.Y., Goodfellow M., Bull A.T., Kim K.H., Bibb M.J., Choi I.G., Stach J.E.
      J. Bacteriol. 193:3391-3392(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AB-18-032Imported.

    Entry informationi

    Entry nameiF4F695_VERMA
    AccessioniPrimary (citable) accession number: F4F695
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3